Hypoxic Pulmonary Vasoconstriction

Cellular and Molecular Mechanisms

AvJason X.-J. Yuan

Häftad, Engelska, 2013

Del i serien Developments in Cardiovascular Medicine

2 503 kr

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Beskrivning

Complete reference on hypoxic pulmonary vasoconstriction and hypoxia-mediated pulmonary hypertension. Can be utilized by the physician-scientist and researcher in the laboratory as both a technical manual and reference. Designed for clinicians to guide and improve clinical treatment and diagnosis of patients with hypoxia mediated pulmonary vascular disease and right heart failure.

Produktinformation

Utgivningsdatum:2013-05-15
Mått:152 x 229 x 33 mm
Vikt:873 g
Format:Häftad
Språk:Engelska
Serie:Developments in Cardiovascular Medicine
Antal sidor:590
Förlag:Springer-Verlag New York Inc.
ISBN:9781475779929

Utforska kategorier

Fysiologi inom Medicin
Olycksfalls- och akutmedicin inom Medicin
Farmakologi inom Medicin

Innehållsförteckning

Physiology and Pathophysiology of Hypoxic Pulmonary Vasoconstriction.- Physiological Function of Hypoxic Pulmonary Vasoconstriction.- Hypoxic Pulmonary Vasoconstriction: Heterogeneity.- The Physics of Hypoxic Pulmonary Hypertension and Its Connection with Gene Actions.- Role of Intra Cellular Ca2+ and Ca2+ Sensitivity in Hypoxic Pulmonary Vasoconstriction.- Ca2+ Sparks in Pulmonary Artery Smooth Muscle Cells: Implications for Hypoxic Pulmonary Vasoconstriction.- Hypoxia-Mediated Regulation of Ca2+ Transients in Pulmonary Artery Smooth Muscle Cells.- Calcium Mobilization by Hypoxia in Pulmonary Artery Smooth Muscle.- Critical Role of Ca+ Sensitization in Acute Hypoxic Pulmonary Vasoconstriction.- Role of Ion Channels in Hypoxic Pulmonary Vasoconstriction.- Regulation of Ion Channels in Pulmonary Artery Smooth Muscle Cells.- Regulation of O2-Sensitive K+ Channels by a Mitochondrial Redox Sensor: Implications for Hypoxic Pulmonary Vasoconstriction.- Hypoxic Regulation of K+ Channel Expression and Function in Pulmonary Artery Smooth Muscle Cells.- Transient Receptor Potential Channels and Capacitative Ca2+ Entry in Hypoxic Pulmonary Vasoconstriction.- Role of Endothelium in Hypoxic Pulmonary Vasoconstriction.- Endothelium-dependent Hypoxic Pulmonary Vasoconstriction.- Mechanisms of Oxygen Sensing in the Pulmonary Vasculature.- Chemistry of Oxygen and Its Derivatives in the Lung.- Interaction of Oxidants With Pulmonary Vascular Signaling Systems.- Mitochondrial Oxygen Sensing in Hypoxic Pulmonary Vasoconstriction.- Redox Oxygen Sensing in Hypoxic Pulmonary Vasoconstriction.- Mitochondrial Diversity in the Vasculature: Implications for Vascular Oxygen Sensing.- Hypoxia, Cell Metabolism, and cADPR Accumulation.- Oxygen-Sensing Mechanisms in Other Organs and Tissues.- Involvement of Intracellular Reactive Oxygen Species in the Control of Gene Expression by Oxygen.- Oxygen Sensing, Oxygen-sensitive Ion Channels and Mitochondrial Function in Arterial Chemoreceptors.- Oxygen Sensing by Adrenomedullary Chromaffin Cells.- Oxygen-sensitive Ion Channels in Pheochromocytoma (PC12) Cells.- Pathology and Mechanisms of Hypoxia-Induced Pulmonary Hypertension.- Pulmonary Vascular Remodeling in Hypoxic Pulmonary Hypertension.- Rho/Rho-kinase Signaling in Hypoxic Pulmonary Hypertension.- Hypoxia-sensitive Transcription Factors and Growth Factors.- Heterogeneity in Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation.- Persistent Pulmonary Hypertension of the Newborn: Pathophysiology and Treatment.- Roles for Vasoconstriction and Gene Expression in Hypoxia-induced Pulmonary Vascular Remodeling.- Polyamine Regulation in Hypoxic Pulmonary Arterial Cells.- Strain Differences of Hypoxia-Induced Pulmonary Hypertension.- Experimental Models for the Study of Hypoxic Pulmonary Vasoconstriction.- Animal and In Vitro Models for Studying Hypoxic Pulmonary Vasoconstriction.- Transgenic and Gene-Targeted Mouse Models in Hypoxic Pulmonary Hypertension Research.- Measurement of Ionic Currents and Intracellular Ca2+ Using Patch Clamp and Fluorescence Microscopy Techniques.