Vaccine Adjuvants

Methods and Protocols

AvGwyn Davies

Häftad, Engelska, 2016

Del i serien Methods in Molecular Biology

1 102 kr

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Beskrivning

Spanning from discoveries in fundamental immunology to industrial and commercial concerns, the study of vaccine adjuvants has developed into an exciting area of work with great, vital potential in innovating techniques in which adjuvants may steer the immune system towards the responses required by unmet vaccination needs.

Produktinformation

Utgivningsdatum:2016-08-23
Mått:178 x 254 x 18 mm
Vikt:612 g
Format:Häftad
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:314
Förlag:Humana Press Inc.
ISBN:9781493957118

Utforska kategorier

Onkologi inom Medicin
Farmakologi inom Medicin

Innehållsförteckning

Immunology of Vaccine Adjuvants.- Preclinical Development of AS04.- Nonclinical Safety Assessment of Vaccines and Adjuvants.- Aluminum Adjuvants: Preparation, Application, Dosage, and Formulation with Antigen.- Freund’s Complete and Incomplete Adjuvants, Preparation, and Quality Control Standards for Experimental Laboratory Animals Use.- Liposomal Adjuvants: Preparation and Formulation with Antigens.- Micro/Nanoparticle Adjuvants: Preparation and Formulation with Antigens.- Adjuvant Activity on Human Cells In Vitro.- Adjuvant Activity on Murine and Human Macrophages.- In Vitro Effects of Adjuvants on B Cells.- NKT Cell Responses to Glycolipid Activation.- Tracking Dendritic Cells In Vivo.- Adjuvant Effects on Antibody Titre.- Functional Antibody Assays.- Determining Adjuvant Activity on T-Cell Function In Vivo: Th Cells.- Quantitative Multiparameter Assays to Measure the Effect of Adjuvants on Human Antigen-Specific CD8 T-Cell Responses.- Large-Animal Model for Establishing E/T Ratio of Adjuvants.- Determining the Activity of Mucosal Adjuvants.- Adjuvant Activity of Cytokines.