Multiplex Biomarker Techniques

Methods and Applications

AvPaul C. Guest

Häftad, Engelska, 2018

Del i serien Methods in Molecular Biology

1 202 kr

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Beskrivning

This detailed book arrives as there is an increasing need for multiplex biomarker readouts for improved clinical management and to support the development of new drugs by pharmaceutical companies, due to continuous technical developments and new insights into the high complexity of many diseases.

Produktinformation

Utgivningsdatum:2018-07-06
Mått:178 x 254 x 19 mm
Vikt:634 g
Format:Häftad
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:317
Förlag:Humana Press Inc.
ISBN:9781493982851

Utforska kategorier

Farmakologi inom Medicin

Innehållsförteckning

Application of Multiplex Biomarker Approaches to Accelerate Drug Discovery and Development.- The Application of Multiplex Biomarker Techniques for Improved Stratification and Treatment of Schizophrenia Patients.- Multiplex Biomarker Approaches in Type 2 Diabetes Mellitus Research.- LC-MSE, Multiplex MS/MS, Ion Mobility, and Label-Free Quantitation in Clinical Proteomics.- Phenotyping Multiple Subsets of Immune Cells In Situ in FFPE Tissue Sections: An Overview of Methodologies.- Identification and Clinical Translation of Biomarker Signatures: Statistical Considerations.- Opportunities and Challenges of Multiplex Assays: A Machine Learning Perspective.- Multiplex Analyses Using Real-Time Quantitative PCR.- Multiplex Analysis Using cDNA Transcriptomic Profiling.- Multiplex Single Nucleotide Polymorphism Analyses.- Pulsed SILAC as a Proteomic Approach for miRNA Targets Identification in Cell Culture.- Blood Bio-SamplingProcedures for Multiplex Biomarkers Studies.- Multiplex Immunoassay Profiling.- Multiplex Sequential Immunopreciptation of Insulin Secretory Granule Proteins from Radiolabeled Pancreatic Islets.- Two Dimensional Gel Electrophoresis of Insulin Secretory Granule Proteins from Biosynthetically-Labeled Pancreatic Islets.- Depletion of Highly Abundant Proteins of the Human Blood Plasma: Applications in Proteomics Studies of Psychiatric Disorders.- Simultaneous Two-Dimensional Difference Gel Electrophoresis (2D-DIGE) Analysis of Three Distinct Proteomes.- Selective Reaction Monitoring for Quantitation of Cellular Proteins.- Characterization of a Protein Interactome by Co-Immunoprecipitation and Shotgun Mass Spectrometry.- Using 15N-Metabolic Labeling for Quantitative Proteomic Analyses.- Multiplex Measurement of Serum Folate Vitamers by UPLC-MS/MS.- UPLC-MS/MS Determination of Deuterated 25-Hydroxyvitamin D (d3-25OHD3) and Other Vitamin D Metabolites for the Measurement of 25OHD Half-Life.- iTRAQ-Based Shotgun Proteomics Approach for Relative Protein Quantification.- 1H NMR Metabolomic Profiling of Human and Animal Blood Serum Samples.- Lab-on-a-Chip Multiplex Assays.- Multiplex Smartphone Diagnostics.- Development of a User-Friendly App for Assisting Anticoagulation Treatment.- Multiplex Biomarker Approaches to Enable Point-of-Care Testing and Personalized Medicine.