Year in Immunology 2008, Volume 1143

Noel R. Rose, MD, PhD, is a Professor of Pathology and of Molecular Microbiology and Immunology at Johns Hopkins University. He is also the Director for the Center for Autoimmune Disease Research at the university.

• Preface: Noel R. Rose. 1. TLR and TLR Signaling: Taro Kawai and Shizuo Akira.2. TLR in Autoimmunity: Maria Fischer and Marc Ehlers.3. CARD9 Signaling in the Innate Immune Response: Jürgen Ruland.4. β-Glucans and Dectin-1: S. Vicky Tsoni and Gordon D. Brown.5. Basic and Clinical Immunology of Siglecs: Stephen von Gunten and Bruce S. Bochner.6. Mast Cells: Multifaceted Immune Cells with Diverse Roles in Health and Disease: Kavitha N. Rao and Melissa A. Brown.7. The Thymus Medulla Slowly Yields Its Secrets: Lars-Oliver Tykocinski, Anna Sinemus, and Bruno Kyewski.8. RANK/RANKL: Regulators of Immune Response and Bone Physiology: Andreas Leibbrandt and Josef M. Penninger.9. Functional Analysis of FOXP3: Jane H. Buckner and Steven F. Ziegler.10. Retinoic Acid in the Immune System: Karina Pino-Lagos, Micah J. Benson, and Randolph J. Noelle.11. Regulation and Function of Proinflammatory TH17 Cells: Gustavo J. Martinez, Roza I. Nurieva, Xuexian O. Yang, and Chen Dong.12. Recalling the Year in Memory T Cells: Nicholas D. Bushard and Donna L. Farber.13. MicroRNAs and Their Emerging Roles in Immunology: Kaleb M. Pauley and Edward K. L. Cha.14. Immunology of Mercury: Jaya Vas and Marc Monestier.15. Anti-CCP Antibody: A Marker for the Early Detection of Rheumatoid Arthritis: Walter J. van Venrooij, Joyce J. B. C. van Beers, and Ger J. M. Pruijn.Index of Contributors