G Protein-Coupled Receptors Handbook

Inbunden, Engelska, 2005

Del i serien Contemporary Clinical Neuroscience

2 239 kr

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Beskrivning

The G Protein-Coupled Receptors handbook provides a comprehensive overview of recent advances in the G protein-coupled receptor (GPCR) field. This volume reviews the recent advances and current knowledge regarding GPCR's from the basics of GPCR structure to dimerization and drug discovery.

Produktinformation

Utgivningsdatum:2005-05-01
Mått:178 x 254 x 28 mm
Vikt:1 005 g
Format:Inbunden
Språk:Engelska
Serie:Contemporary Clinical Neuroscience
Antal sidor:412
Upplaga:2005
Förlag:Humana Press Inc.
ISBN:9781588293657

Utforska kategorier

Medicin: allmänt inom Medicin

Recensioner i media

"...provides an excellent resource to introduce the reader to many of the diverse areas and questions that drive research in the GCPR field." -TRENDS in Endocrinology and Metablosim

Innehållsförteckning

GPCRs: Structure and Function.- Structure—Function Relationships in G Protein-Coupled Receptors.- Molecular Mechanisms Involved in the Activation of Rhodopsin-Like Seven-Transmembrane Receptors.- GPCR Folding and Maturation.- Regulated Membrane Trafficking and Proteolysis of GPCRs.- GPCR Activity and Its Regulators.- Heterotrimeric G Proteins and Their Effector Pathways.- RGS Proteins.- G Protein-Coupled Receptor Kinases.- Regulators of GPCR Activity.- GPCR Interacting Proteins.- GPCR Dimerization/Oligomerization.- Biophysical and Biochemical Methods to Study GPCR Oligomerization.- Oligomerization Domains of G Protein-Coupled Receptors.- Functional Complementation and the Analysis of GPCR Dimerization.- The Role of Oligomerization in G Protein-Coupled Receptor Maturation.- Receptor Oligomerization and Trafficking.- Modulation of Receptor Pharmacology by G Protein-Coupled Receptor Dimerization.- Recent Developments in Drug Discovery.- Role of Heteromeric GPCR Interactions in Pain/Analgesia.- Conformational Plasticity of GPCR Binding Sites.- De-Orphanizing GPCRs and Drug Development.