This resource guides health care professionals through the preparticipation evaluation (PPE) process in the medical home for youth in middle school through college who are participating in athletics or other organized activities requiring a physician's evaluation.Included are recommendations on PPE timing, setting, and structure; medical history questions; and how to determine participation eligibility. This resource also lists return-to-play guidelines, addresses medicolegal and ethical concerns, and discusses implementation in practice. Contents cover physical examination and eligibility, systems-based examinations, cardiovascular problems, central nervous system, respiratory, gastrointestinal and urogenital, musculoskeletal, dermatologic, mental health, and more.New to the 6th edition Hematologic and Oncologic Considerations Sports Nutrition and Dietary Habits Preventing and Addressing Sexual Abuse and Violence The PPE: Preparticipation Evaluation, 6th Edition is nationally endorsed by the the American Heart Association, National Athletic Trainers' Association, and National Federation of State High School Associations.