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Beskrivning
Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases.
"Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease." -Immunology News
Innehållsförteckning
I: Cytokines: Induction and Regulation.- 1 Transcriptional Regulation of Cytokine Gene Expression in Th Subsets.- 2 Chromatin Remodeling and Transcriptional Regulation of Cytokine Gene Expression in T Cells.- 3 Variant Ligands, Altered T Cell Receptor Signaling, Hierarchial Response Thresholds, and CD4+ Effector Responses.- 4 The Role of Costimulation in T Cell Differentiation.- 5 CD I d-Restricted NK T Cells and Autoimmunity.- 6 Role of T Cell Death and Cytokines in Autoimmunity.- 7 Role of Chemokines and Their Receptors in the Induction and Regulation of Autoimmune Disease.- II: Cytokines: Role in Specific Autoimmune Diseases.- 8 Cytokines and Resistance to Organ Specific Autoimmune Disease.- 9 The Role of Cytokines in Induction and Regulation of Autoimmune Uveitis.- 10 Pathogenic and Regulatory Cytokines in Experimental Autoimmune Encephalomyelitis.- 11 Role of Cytokines in Multiple Sclerosis and in Mucosal Tolerance.- 12 Cytokines and Human Type 1 Diabetes.- 13 Cytokines in Human Rheumatoid Arthritis and Murine Models.- 14 Systemic Lupus Erythematosus.- 15 Myasthenia Gravis.- III: Cytokines and Autoimmunity: A Synthesis.- 16 Cytokines in Autoimmune Disease.