Reverse Transcriptase Inhibitors in HIV/AIDS Therapy

Häftad, Engelska, 2010

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Beskrivning

A magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS.

Produktinformation

Utgivningsdatum:2010-11-19
Mått:152 x 229 x 31 mm
Vikt:789 g
Format:Häftad
Språk:Engelska
Serie:Infectious Disease
Antal sidor:528
Förlag:Humana Press Inc.
ISBN:9781617376955

Utforska kategorier

Sjukdomar och rubbningar inom Medicin

Recensioner i media

From the reviews: "This book will appeal to medical students needing a detailed review of area ... . It is most suitable for libraries ... . The individual chapters are authoritative and comprehensive ... . a source for in-depth and specific information." (Mark Harris, Microbiology Today, November, 2006)

Innehållsförteckning

Structural Studies on HIV Reverse Transcriptase Related to Drug Discovery.- Zidovudine, Lamivudine, and Abacavir.- Stavudine, Didanosine, and Zalcitabine.- Emtricitabine.- Nucleotide Analogs.- Resistance to Nucleoside and Nucleotide Reverse Transcriptase Inhibitors.- Pharmacokinetics of Reverse Transcriptase Inhibitors.- Peripheral Neuropathy Associated With Nucleoside Reverse Transcriptase Inhibitor Therapy.- Mitochondrial Dysfunction and Nucleoside Reverse Transcriptase Inhibitor Therapy.- Mitochondrial Toxicity and Lipodystrophy.- Nevirapine.- Efavirenz.- Delavirdine.- Resistance to Non-Nucleoside Reverse Transcriptase Inhibitors.- Vertical Transmission of HIV and Therapeutic Interventions.- New Reverse Transcriptase Inhibitors in Development.- Antiretroviral Drugs for Millions.