BLyS Ligands and Receptors

Häftad, Engelska, 2012

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Beskrivning

Discovery of the BLyS (also known as BAFF) family of ligands and receptors has yielded a paradigm shift in our view of B-lymphocyte selection, survival, activation, and homeostasis.

Produktinformation

Utgivningsdatum:2012-02-25
Mått:155 x 235 x 17 mm
Vikt:464 g
Format:Häftad
Språk:Engelska
Serie:Contemporary Immunology
Antal sidor:284
Upplaga:2010
Förlag:Humana Press Inc.
ISBN:9781617796517

Utforska kategorier

Onkologi inom Medicin

Innehållsförteckning

The Beautiful Structures of BAFF, APRIL, and Their Receptors.- BAFF Receptor Regulation of Peripheral B-Lymphocyte Survival and Development.- Regulation of B-Cell Self-Tolerance By BAFF and the Molecular Basis of Its Action.- Role of BAFF and APRIL in Antibody Production and Diversification.- Signal Transduction by Receptors for BAFF and APRIL.- TACI Signaling and Its Role in Immunity.- The BAFF/APRIL System in Autoimmunity.- Systemic Immune-Based Rheumatic Diseases: Blissless States of BLySfulness.- The Role of BAFF and APRIL in Regulating Human B-Cell Behaviour: Implications for Disease Pathogenesis.- Translation of BAFF Inhibition from Mouse to Non-human Primate and Human.- BLyS/BR3 Receptor Signaling in the Biology and Pathophysiology of Aggressive B-Cell Lymphomas.- Tipping the Scales of Survival: The Role of BLyS in B-Cell Malignancies.