From the reviews: "This substantive book is a compilation of focused reviews and laboratory protocols for biomarkers associated with melanoma and related targeted therapies. ... This would be useful to anyone interested in melanoma, from clinicians wanting an update on promising molecular targets for melanoma treatment to researchers wanting detailed protocols for diagnostic or treatment monitoring assays. ... If you are working in melanoma research or treating patients with melanoma, you will very much appreciate this book." (Valerie L. Ng, Doody's Book Reviews, March, 2014)

• ​Novel Insights/translational Implication from the Emerging Biology of Melanoma.- Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era.- Integrating Molecular Biomarkers Into Current Clinical Management In Melanoma.- Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers.- Immunologic Monitoring of Cancer Vaccine Trials Using the ELISPOT Assay.- Markers for Anti-Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma.- Marker Utility for Combination Therapy.- Assaying for BRAF V600E in Tissue and Blood in Melanoma.- Selecting Patients for KIT Inhibition in Melanoma.- Detecting Mechanisms of Acquired BRAF inhibitor Resistance in Melanoma.- Current Status of Diagnostic and Prognostic Markers in Melanoma.- Chromosomal Copy Number Analysis in Melanoma Diagnostics.- Construction and Analysis of Multi-Parameter Prognostic Models for Melanoma Outcome.- Immunohistochemical Diagnostic and Prognostic Markers for Melanoma.- Lymphatic Invasion as a Prognostic Biomarker in Primary Cutaneous Melanoma.- Tumor Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis.- Pathological Staging of Melanoma.- Genotyping of Human Leukocyte Antigen (HLA) Ancestral Haplotypes as Prognostic Marker in Cancer Using PCR Analysis.- B7-H Abnormalities in Melanoma and Clinical Relevance.- Melanoma Susceptibility Genes and Risk Assessment.- Clinical, Pathologic, and Imaging Features, and Biological Markers of Uveal Melanoma.- A Prognostic Test to Predict Risk of Metastasis in Uveal Melanoma Based on a 15-Gene Expression Profile.- Molecular Karyotyping for Detection of Prognostic Markers in Fine Needle Aspirate Biopsy Samples of Uveal Melanoma.- ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment.- Epigenetic Markers of Prognosis in Melanoma.- Isolation of Melanoma Cell Subpopulations Using Negative Selection.- Circulating Tumor Cells as Prognostic Biomarkers in Cutaneous Melanoma Patients.- Detection ofChondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma.- Targeting Damage Associated Molecular Pattern Molecules (DAMPs) and DAMP Receptors in Melanoma.- The Clinical Use of PET/CT in the Evaluation of Melanoma.- Immune System Functional Pathway Analysis Using Single Cell Network Profiling (SCNP): A Novel Tool in Cancer Immunotherapy.- Quantitative and Spatial Image Analysis of Tumor and Draining Lymph Nodes Using Immunohistochemistry and High Resolution Multispectral Imaging to Predict Metastasis.- COLD-PCR Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic Testing.- Isolation of Circulating MicroRNAs from Microvesicles found in Human Plasma.- Detection of Circulating Tumor Cells by Photoacustic Flowmetry.- Statistical Design and Evaluation of Biomarker Studies.- Tissue Resources for Clinical Use and Marker Studies in Melanoma.

From the reviews: "This substantive book is a compilation of focused reviews and laboratory protocols for biomarkers associated with melanoma and related targeted therapies. ... This would be useful to anyone interested in melanoma, from clinicians wanting an update on promising molecular targets for melanoma treatment to researchers wanting detailed protocols for diagnostic or treatment monitoring assays. ... If you are working in melanoma research or treating patients with melanoma, you will very much appreciate this book." (Valerie L. Ng, Doody's Book Reviews, March, 2014)

• ​Novel Insights/translational Implication from the Emerging Biology of Melanoma.- Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era.- Integrating Molecular Biomarkers Into Current Clinical Management In Melanoma.- Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers.- Immunologic Monitoring of Cancer Vaccine Trials Using the ELISPOT Assay.- Markers for Anti-Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma.- Marker Utility for Combination Therapy.- Assaying for BRAF V600E in Tissue and Blood in Melanoma.- Selecting Patients for KIT Inhibition in Melanoma.- Detecting Mechanisms of Acquired BRAF inhibitor Resistance in Melanoma.- Current Status of Diagnostic and Prognostic Markers in Melanoma.- Chromosomal Copy Number Analysis in Melanoma Diagnostics.- Construction and Analysis of Multi-Parameter Prognostic Models for Melanoma Outcome.- Immunohistochemical Diagnostic and Prognostic Markers for Melanoma.- Lymphatic Invasion as a Prognostic Biomarker in Primary Cutaneous Melanoma.- Tumor Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis.- Pathological Staging of Melanoma.- Genotyping of Human Leukocyte Antigen (HLA) Ancestral Haplotypes as Prognostic Marker in Cancer Using PCR Analysis.- B7-H Abnormalities in Melanoma and Clinical Relevance.- Melanoma Susceptibility Genes and Risk Assessment.- Clinical, Pathologic, and Imaging Features, and Biological Markers of Uveal Melanoma.- A Prognostic Test to Predict Risk of Metastasis in Uveal Melanoma Based on a 15-Gene Expression Profile.- Molecular Karyotyping for Detection of Prognostic Markers in Fine Needle Aspirate Biopsy Samples of Uveal Melanoma.- ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment.- Epigenetic Markers of Prognosis in Melanoma.- Isolation of Melanoma Cell Subpopulations Using Negative Selection.- Circulating Tumor Cells as Prognostic Biomarkers in Cutaneous Melanoma Patients.- Detection ofChondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma.- Targeting Damage Associated Molecular Pattern Molecules (DAMPs) and DAMP Receptors in Melanoma.- The Clinical Use of PET/CT in the Evaluation of Melanoma.- Immune System Functional Pathway Analysis Using Single Cell Network Profiling (SCNP): A Novel Tool in Cancer Immunotherapy.- Quantitative and Spatial Image Analysis of Tumor and Draining Lymph Nodes Using Immunohistochemistry and High Resolution Multispectral Imaging to Predict Metastasis.- COLD-PCR Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic Testing.- Isolation of Circulating MicroRNAs from Microvesicles found in Human Plasma.- Detection of Circulating Tumor Cells by Photoacustic Flowmetry.- Statistical Design and Evaluation of Biomarker Studies.- Tissue Resources for Clinical Use and Marker Studies in Melanoma.

From the reviews: "This substantive book is a compilation of focused reviews and laboratory protocols for biomarkers associated with melanoma and related targeted therapies. ... This would be useful to anyone interested in melanoma, from clinicians wanting an update on promising molecular targets for melanoma treatment to researchers wanting detailed protocols for diagnostic or treatment monitoring assays. ... If you are working in melanoma research or treating patients with melanoma, you will very much appreciate this book." (Valerie L. Ng, Doody's Book Reviews, March, 2014)

• ​Novel Insights/translational Implication from the Emerging Biology of Melanoma.- Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era.- Integrating Molecular Biomarkers Into Current Clinical Management In Melanoma.- Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers.- Immunologic Monitoring of Cancer Vaccine Trials Using the ELISPOT Assay.- Markers for Anti-Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma.- Marker Utility for Combination Therapy.- Assaying for BRAF V600E in Tissue and Blood in Melanoma.- Selecting Patients for KIT Inhibition in Melanoma.- Detecting Mechanisms of Acquired BRAF inhibitor Resistance in Melanoma.- Current Status of Diagnostic and Prognostic Markers in Melanoma.- Chromosomal Copy Number Analysis in Melanoma Diagnostics.- Construction and Analysis of Multi-Parameter Prognostic Models for Melanoma Outcome.- Immunohistochemical Diagnostic and Prognostic Markers for Melanoma.- Lymphatic Invasion as a Prognostic Biomarker in Primary Cutaneous Melanoma.- Tumor Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis.- Pathological Staging of Melanoma.- Genotyping of Human Leukocyte Antigen (HLA) Ancestral Haplotypes as Prognostic Marker in Cancer Using PCR Analysis.- B7-H Abnormalities in Melanoma and Clinical Relevance.- Melanoma Susceptibility Genes and Risk Assessment.- Clinical, Pathologic, and Imaging Features, and Biological Markers of Uveal Melanoma.- A Prognostic Test to Predict Risk of Metastasis in Uveal Melanoma Based on a 15-Gene Expression Profile.- Molecular Karyotyping for Detection of Prognostic Markers in Fine Needle Aspirate Biopsy Samples of Uveal Melanoma.- ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment.- Epigenetic Markers of Prognosis in Melanoma.- Isolation of Melanoma Cell Subpopulations Using Negative Selection.- Circulating Tumor Cells as Prognostic Biomarkers in Cutaneous Melanoma Patients.- Detection ofChondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma.- Targeting Damage Associated Molecular Pattern Molecules (DAMPs) and DAMP Receptors in Melanoma.- The Clinical Use of PET/CT in the Evaluation of Melanoma.- Immune System Functional Pathway Analysis Using Single Cell Network Profiling (SCNP): A Novel Tool in Cancer Immunotherapy.- Quantitative and Spatial Image Analysis of Tumor and Draining Lymph Nodes Using Immunohistochemistry and High Resolution Multispectral Imaging to Predict Metastasis.- COLD-PCR Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic Testing.- Isolation of Circulating MicroRNAs from Microvesicles found in Human Plasma.- Detection of Circulating Tumor Cells by Photoacustic Flowmetry.- Statistical Design and Evaluation of Biomarker Studies.- Tissue Resources for Clinical Use and Marker Studies in Melanoma.