Advanced Studies in Experimental and Clinical Medicine

P. Mereena Luke is a Research Scholar in the Department of Polymer Technology, Chemical Faculty, at Gdansk University of Technology, Poland. She recently completed a two-year project sponsored by the University Grants Commission on “Preparation and Evaluation of Dendrimeric Nano Systems for Drug Delivery Applications” at the International and Inter University Center for Nanoscience and Nanotechnology, Mahatma Gandhi University, India. She has published articles in international and national professional journals and has also presented her work at international and national conferences.K. R. Dhanya, PhD, is a Postdoctoral Fellow at the International and Inter University Center for Nanoscience and Nanotechnology, Mahatma Gandhi University, India. She has published articles in international and national journals and has presented her work at international and national conferences as well. She has also authored and co-authored several book chapters. Didier Rouxel, PhD, is a Professor at the Institut Jean Lamour, Université de Lorraine, France. He has over 100 publications to his name, including over 60 papers in international journals, as well as book chapters, invited conference presentations, seminars, and other communications. He is a member of the French Society of Nanomedicine and was the PhD thesis director for several prize-winning theses.Nandakumar Kalarikkal, PhD, is the Director of the International and Inter University Centre for Nanoscience and Nanotechnology as well as the Director and Assistant Professor in the School of Pure and Applied Physics at Mahatma Gandhi University, India. He has published more than 160 research articles in peer-reviewed journals and has edited 20 books. He has four patents to his credit. Dr. Nandakumar was honored by being named “Professor at Lorraine” by the University of Lorraine, France, for his academic excellence.Sabu Thomas, PhD, DSc, FRSC, is the Vice Chancellor of Mahatma Gandhi University, Kottayam, Kerala, India, and Professor of Polymer Science and Engineering at the School of Chemical Sciences as well as Founder Director of the International and Inter University Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University, Kottayam, India. He received the coveted Sukumar Maithy Award proclaiming him the best polymer researcher in the country for the year 2008 as well as many other awards. He has over 800 publications to his credit.

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• Section 1 1. Developments of Health Care: A Brief History of Medicine 2. Immunomodulatory Effect of Plant-Based Extracts on Neurodegeneration 3. Bio-Implants Derived from Biocompatible and Biodegradable Biopolymeric Materials 4. Versatile Nature of Poly(Vinylpyrrolidone) in Clinical Medicine 5. Heat Shock Protein 90 (Hsp90) Inhibitory Potentials of Some Chalcone Compounds as Novel Anti-Proliferative Candidates 6. Perspectives of Cashew Nut Shell Liquid (CNSL) in a Pharmacotherapeutic Context 7. Role of Tandem Mass Spectrometry in Diagnosis and Management of Inborn Errors of Metabolism Section 2 8. Elevated Cytosolic Phospholipase A2αas a Target for Treatment and Prevention the Progression of Neurodegenerative Diseases 9. Real-Time Biospeckle Monitoring of Drug Action in Trypanosoma cruzi Parasites 10. Hirakbhasma: A Potential Ayurvedic Antibacterial Drug Assessed by in vitro Pre-Clinical Studies 11. Pathophysiology of Fluorosis and Calcium Dose Prediction for Its Reversal in Children: Mathematical Modeling, Analysis, and Simulation of Three Clinical Case Studies 12. Diagnosis of Mycobacterium tuberculosis from Sputum DNA Using Multiplex PCR 13. Anti-HSV and Cytotoxicity Properties of Three Different Nanoparticles Derived from an Indian Medicinal Plants 14. A Positive Correlation between IGg2 Antibody Preponderance and Clearance of HSV during Active HSV Infections 15. Effects of Thermal Cycling on Surface Hardness, Diametral Tensile Strength, and Porosity of zn Organically Modified Ceramic (Ormocer) Based Visible Light Cure Dental Restorative Resin