Under the Flavian Emperors the Roman public's hunger for gladiatorial combat has never been greater. The Emperor Domitian's passion for novelty and variety in the arena has given rise to a very different kind of warrior: the Gladiatrix. Lysandra, member of an ancient Spartan sect of warrior priestesses, is the sole survivor of a shipwreck off the coast of Asia Minor who finds herself the property of Lucius Balbus owner of the foremost Ludus for female gladiators in the Eastern Empire. Lysandra's Spartan pride refuses to accept her new status as a slave. Her deadly combat skills not only enable her to survive but win the adoration of the crowds, the respect of her Lanista, Balbus, and the admiration of Sextus Julius Frontinus, the provincial governor. But Lysandra's hubris has stirred up the ethnic factions of the ludus attracting the enmity of the Dacian warrior, Sorina, Gladiatrix Prima and leader of the Barbarian faction as well as inciting the hatred of the sadistic Numidian trainer Nastasen. Meanwhile Frontinus and Balbus plan the ultimate combat spectacle for the visit of the emperor's emissary, Trajanus, that will involve Lysandra in her greatest and deadliest trial.
