HIV-1 Latency

Inbunden, Engelska, 2018

Del 417 i serien Current Topics in Microbiology and Immunology

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Beskrivning

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. assays and technical approaches to quantify viral reservoirs in humans and animal models;

Produktinformation

Utgivningsdatum:2018-10-25
Mått:155 x 235 x 20 mm
Vikt:506 g
Format:Inbunden
Språk:Engelska
Serie:Current Topics in Microbiology and Immunology
Antal sidor:248
Upplaga:18001
Förlag:Springer Nature Switzerland AG
ISBN:9783030028152

Utforska kategorier

Infektionssjukdomar och smittsamma sjukdomar inom Medicin
Patologi inom Medicin
Onkologi inom Medicin

Mer om författaren

Guido SilvestriEmory University School of Medicine, Atlanta, GA 30329, USAgsilves@emory.eduMathias LichterfeldThe Brigham and Women’s Hospital and the Ragon Institute of MGH, MIT and Harvard, Boston, MA, USAMLICHTERFELD@mgh.harvard.edu

Innehållsförteckning

Molecular Control of HIV and SIV Latency.- Assays to Measure Latency, Reservoirs and Reactivation.- The Antiviral Immune Response and its Impact on the HIV-1 Reservoir.- Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy.- SIV Latency in Macrophages in the CNS.- Mathematical models of HIV latency.- Residual Immune Activation and Latency.- Immune Interventions to Eliminate the HIV Reservoir.- Cell and Gene Therapy for HIV Cure.