Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori

Inbunden, Engelska, 2019

Del i serien Current Topics in Microbiology and Immunology

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Beskrivning

pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations.

Produktinformation

Utgivningsdatum:2019-06-05
Mått:155 x 235 x 27 mm
Vikt:740 g
Format:Inbunden
Språk:Engelska
Serie:Current Topics in Microbiology and Immunology
Antal sidor:359
Förlag:Springer Nature Switzerland AG
ISBN:9783030151379

Utforska kategorier

Gastrointestinal och kolorektal kirurgi inom Medicin
Fysiologi inom Medicin
Patologi inom Medicin

Mer om författaren

Prof. Dr. rer. nat. Steffen BackertChair of MicrobiologyFriedrich Alexander University Erlangen/NurembergDepartment of BiologyDivision of MicrobiologyStaudtstr. 5D-91058 ErlangenGermanyTel. ++49 9131 8528081Fax ++49 9131 8528082

Innehållsförteckning

Inflammation, immunity and vaccine development for the gastric pathogen Helicobacter pylori.- Impact of Helicobacter pylori Virulence Factors on the Host immune Response and Gastric Pathology.- Genetic polymorphisms in inflammatory and other regulators in gastric cancer: risks and clinical consequences.- MALT lymphoma as a model of chronic inflammation-induced gastric tumor development.- Crosstalk between DNA damage and inflammation in the multiple steps of gastric carcinogenesis.- Importance of toll-like receptors in pro-inflammatory and anti-inflammatory responses by Helicobacter pylori infection.- Role of NOD1 and ALPK1/TIFA signalling in innate immunity against Helicobacter pylori infection.- Carbohydrate-dependent and antimicrobial peptide defense mechanisms against Helicobacter pylori infections.- The sweeping role of cholesterol depletion in the persistence of Helicobacter pylori infections.- Helicobacter pylori deregulates T and B cell signaling to trigger immune evasion.- Mechanisms of inflammasome signaling, microRNA induction and resolution of inflammation by Helicobacter pylori.- Impact of the gastrointestinal microbiome in health and disease: co-evolution with the host immune system.- Resolution of gastric cancer-promoting inflammation: a novel strategy for anti-cancer therapy.