Haralampos M. Moutsopoulos, MD, FACP, FRCP is an Emeritus Professor of the Medical School, University of Athens, Greece and active Member of Athens Academy holding the chair of Medical sciences-Immunology. His research has contributed to current understanding of the clinical aspects, pathogenesis and therapy of autoimmune rheumatic disorders. He is considered a world authority on Sjögren's syndrome (autoimmune Epithelitis). His scientific work is extensively cited (>51000, h factor >110) and he has been awarded with numerous national and international awards.Evangelia Zampeli, MD, PhD is a Consultant Rheumatologist in Bioclinic General Hospital of Athens and Associate Member of the Institute for Autoimmune Systemic and Neurological Disorders, Athens, Greece. She has obtained her PhD on Immunopharmacology and continues her research which is concentrated on clinical and immunologic aspects of systemic autoimmune diseases.Panayiotis G. Vlachoyiannopoulos, MD, PhD is Professor of Medicine and Immunology at the University of Athens, School of Medicine. He has studied the clinical presentation, epidemiology and pathogenic aspects of systemic autoimmune connective tissue diseases using as a disease model of the antiphospholipid syndrome. He has written extensively on these topics and has published 126 peer reviewed articles.Jacques-Olivier Pers, DDS, PhD is Professor of Immunology and Director of the INSERM research team UMR1227 “B cells and autoimmunity” at the University of Brest, Laboratory of Immunology, France. His research focuses on immunopathology and immunotherapy dedicated to the study of normal and pathological B cells. He has studied different disease models of autoimmune diseases (Sjögren’s syndrome, systemic lupus erythematosus, rheumatoid arthritis), lymphoproliferative disorders (chronic lymphocytic leukemia), and kidney graft rejection from upstream approaches (epigenetics and autoimmunity, the genetic control of BAFF, calcium signaling, regulatory B cells) to downstream approaches (multicenter clinical trials, IVIg, patents).

• Part I An Introductory Approach to Autoimmune Disorders.- Basic Immunology.- Autoimmune Rheumatic Disorders: Pathogenetic and Laboratory Aspects.- Part II Autoimmune Rheumatic (Connective Tissue) Diseases.- Inflammatory Arthritis.- Systemic Lupus Erythematosus, Antiphospholipid Syndrome, and Mixed Connective Tissue Disease.- Inflammatory Muscle Disease.- Sjögren’s Syndrome, IgG4-Related Disorders.- Systemic Sclerosis.- Vasculitides and Related Diseases.- Autoinflammatory Syndromes.- Part III Rheumatic Disorders and Manifestations in Various Organs, Systems and Disciplines.- The Skin, the Eyes, and the Ears in Rheumatic Diseases.- Rheumatic Disorders Associated with Metabolic, Endocrine, and Hematological Diseases.- Bone, Cartilage, and Soft Tissue Disorders.- Rheumatic Manifestations: A Compilation.- Part IV Treatment and Management of Rheumatic Diseases.- Medications, Therapeutic Modalities, and Regimens Used in the Management of Rheumatic Diseases.

Haralampos M. Moutsopoulos, MD, FACP, FRCP is an Emeritus Professor of the Medical School, University of Athens, Greece and active Member of Athens Academy holding the chair of Medical sciences-Immunology. His research has contributed to current understanding of the clinical aspects, pathogenesis and therapy of autoimmune rheumatic disorders. He is considered a world authority on Sjögren's syndrome (autoimmune Epithelitis). His scientific work is extensively cited (>51000, h factor >110) and he has been awarded with numerous national and international awards.Evangelia Zampeli, MD, PhD is a Consultant Rheumatologist in Bioclinic General Hospital of Athens and Associate Member of the Institute for Autoimmune Systemic and Neurological Disorders, Athens, Greece. She has obtained her PhD on Immunopharmacology and continues her research which is concentrated on clinical and immunologic aspects of systemic autoimmune diseases.Panayiotis G. Vlachoyiannopoulos, MD, PhD is Professor of Medicine and Immunology at the University of Athens, School of Medicine. He has studied the clinical presentation, epidemiology and pathogenic aspects of systemic autoimmune connective tissue diseases using as a disease model of the antiphospholipid syndrome. He has written extensively on these topics and has published 126 peer reviewed articles.Jacques-Olivier Pers, DDS, PhD is Professor of Immunology and Director of the INSERM research team UMR1227 “B cells and autoimmunity” at the University of Brest, Laboratory of Immunology, France. His research focuses on immunopathology and immunotherapy dedicated to the study of normal and pathological B cells. He has studied different disease models of autoimmune diseases (Sjögren’s syndrome, systemic lupus erythematosus, rheumatoid arthritis), lymphoproliferative disorders (chronic lymphocytic leukemia), and kidney graft rejection from upstream approaches (epigenetics and autoimmunity, the genetic control of BAFF, calcium signaling, regulatory B cells) to downstream approaches (multicenter clinical trials, IVIg, patents).

• Part I An Introductory Approach to Autoimmune Disorders.- Basic Immunology.- Autoimmune Rheumatic Disorders: Pathogenetic and Laboratory Aspects.- Part II Autoimmune Rheumatic (Connective Tissue) Diseases.- Inflammatory Arthritis.- Systemic Lupus Erythematosus, Antiphospholipid Syndrome, and Mixed Connective Tissue Disease.- Inflammatory Muscle Disease.- Sjögren’s Syndrome, IgG4-Related Disorders.- Systemic Sclerosis.- Vasculitides and Related Diseases.- Autoinflammatory Syndromes.- Part III Rheumatic Disorders and Manifestations in Various Organs, Systems and Disciplines.- The Skin, the Eyes, and the Ears in Rheumatic Diseases.- Rheumatic Disorders Associated with Metabolic, Endocrine, and Hematological Diseases.- Bone, Cartilage, and Soft Tissue Disorders.- Rheumatic Manifestations: A Compilation.- Part IV Treatment and Management of Rheumatic Diseases.- Medications, Therapeutic Modalities, and Regimens Used in the Management of Rheumatic Diseases.

Haralampos M. Moutsopoulos, MD, FACP, FRCP is an Emeritus Professor of the Medical School, University of Athens, Greece and active Member of Athens Academy holding the chair of Medical sciences-Immunology. His research has contributed to current understanding of the clinical aspects, pathogenesis and therapy of autoimmune rheumatic disorders. He is considered a world authority on Sjögren's syndrome (autoimmune Epithelitis). His scientific work is extensively cited (>51000, h factor >110) and he has been awarded with numerous national and international awards.Evangelia Zampeli, MD, PhD is a Consultant Rheumatologist in Bioclinic General Hospital of Athens and Associate Member of the Institute for Autoimmune Systemic and Neurological Disorders, Athens, Greece. She has obtained her PhD on Immunopharmacology and continues her research which is concentrated on clinical and immunologic aspects of systemic autoimmune diseases.Panayiotis G. Vlachoyiannopoulos, MD, PhD is Professor of Medicine and Immunology at the University of Athens, School of Medicine. He has studied the clinical presentation, epidemiology and pathogenic aspects of systemic autoimmune connective tissue diseases using as a disease model of the antiphospholipid syndrome. He has written extensively on these topics and has published 126 peer reviewed articles.Jacques-Olivier Pers, DDS, PhD is Professor of Immunology and Director of the INSERM research team UMR1227 “B cells and autoimmunity” at the University of Brest, Laboratory of Immunology, France. His research focuses on immunopathology and immunotherapy dedicated to the study of normal and pathological B cells. He has studied different disease models of autoimmune diseases (Sjögren’s syndrome, systemic lupus erythematosus, rheumatoid arthritis), lymphoproliferative disorders (chronic lymphocytic leukemia), and kidney graft rejection from upstream approaches (epigenetics and autoimmunity, the genetic control of BAFF, calcium signaling, regulatory B cells) to downstream approaches (multicenter clinical trials, IVIg, patents).

• Part I An Introductory Approach to Autoimmune Disorders.- Basic Immunology.- Autoimmune Rheumatic Disorders: Pathogenetic and Laboratory Aspects.- Part II Autoimmune Rheumatic (Connective Tissue) Diseases.- Inflammatory Arthritis.- Systemic Lupus Erythematosus, Antiphospholipid Syndrome, and Mixed Connective Tissue Disease.- Inflammatory Muscle Disease.- Sjögren’s Syndrome, IgG4-Related Disorders.- Systemic Sclerosis.- Vasculitides and Related Diseases.- Autoinflammatory Syndromes.- Part III Rheumatic Disorders and Manifestations in Various Organs, Systems and Disciplines.- The Skin, the Eyes, and the Ears in Rheumatic Diseases.- Rheumatic Disorders Associated with Metabolic, Endocrine, and Hematological Diseases.- Bone, Cartilage, and Soft Tissue Disorders.- Rheumatic Manifestations: A Compilation.- Part IV Treatment and Management of Rheumatic Diseases.- Medications, Therapeutic Modalities, and Regimens Used in the Management of Rheumatic Diseases.