This book constitutes the proceedings of the 17th IFIP WG 10.3 International Conference on Network and Parallel Computing, NPC 2020, held in Zhengzhou, China, in September 2020.The 34 full and 7 short papers presented in this volume were carefully reviewed and selected from 95 submissions. They were organized in topical sections named: accelerator; AI; algorithm; architecture and hardware; big data and cloud; edge computing; emerging; network; and storage.