Carbonic Anhydrases: Current and Emerging Therapeutic Targets

AvW. Richard Chegwidden,Nicholas D. Carter

Inbunden, Engelska, 2021

Del 75 i serien Progress in Drug Research

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Beskrivning

The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years.

Produktinformation

Utgivningsdatum:2021-10-31
Mått:155 x 235 x 22 mm
Vikt:617 g
Format:Inbunden
Språk:Engelska
Serie:Progress in Drug Research
Antal sidor:288
Förlag:Springer Nature Switzerland AG
ISBN:9783030795108

Utforska kategorier

Innehållsförteckning

Dedication.- Preface.-The carbonic anhydrases in health and disease.- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets.- Targeting carbonic anhydrases in vascular and pulmonary disease.- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema.- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders.- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes.- An overview of carbonic anhydrase-related neoplasms.- The carbonic anhydrase IX interactome and the regulation of cancer progression.- Carbonic anhydrase IX: current and emerging therapies.- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents.- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening.- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.