This volume constitutes the refereed proceedings of the workshops held at the 32nd International Conference on Database and Expert Systems Applications, DEXA 2021, held in a virtual format in September 2021: The 12^th  International Workshop on Biological Knowledge Discovery from Data (BIOKDD 2021), the 5^th  International Workshop on Cyber-Security and Functional Safety in Cyber-Physical Systems (IWCFS 2021), the 3^rd  International Workshop on Machine Learning and Knowledge Graphs (MLKgraphs 2021), the 1^st  International Workshop on Artificial Intelligence for Clean, Affordable and Reliable Energy Supply (AI-CARES 2021), the 1^st  International Workshop on Time Ordered Data (ProTime2021), and the 1^st  International Workshop on AI System Engineering: Math, Modelling and Software (AISys2021). Due to the COVID-19 pandemic the conference and workshops were held virtually.