Infectious Lesions of the Central Nervous System

Vsevolod A. Zinserling (Tsinzerling) was born 1954 in Leningrad (Russia) in the family of Prof. Dr. Alexander Zinserling (1923-1995) - outstanding pathologist.  He graduated from Leningrad Paediatric Medical Institute in 1977, worked as research scientist, practicing as pathologist in Leningrad Research Institute of Children’s Infections (1977-1988). In 1978-80 had postgraduate training at the chair of pathology (chief. Prof. O.K. Khmelnitsky) of Leningrad Institute for Postgraduate Medical Training. 1981 defended his cand. med. sc. ( Dr. med.) thesis “Brain changes in mycoplasmosis”. In 1988-92 chief of the Central Research Laboratory of Leningrad Paediatric Medical Institute. In 1988 defended the doct. med. sci. thesis “Brain lesions due to respiratory viruses”.  In 1992-2007 chief of the Institute of Pathology St. Petersburg Paediatric Medical Academy. He is also since 1990 providing consultations in the city’s Consulting Centre for the Infectious Pathology at SP BotkinClinical Infectious Hospital. Author of more than 300 scientific publications devoted to different topics of infectious, perinatal and brain pathology, including manuals (in Russian) “Modern Infections” (2002), “Perinatal infections (2002)”, “Infections of the Nervous System” (2011).  In 2021 has published by Springer " Infectious Pathology of the Respiratory Tract". Participant of many international congresses, being invited lecturer at European Congresses of ESP (2010-2021).

• Introduction.- Chapter 1. Epidemiology, morbidity and mortality due to brain pathology associated with biological pathogens.- Chapter 2 Microbiology and molecular biology in the diagnostics.- Chapter 3 Local immunity of the brain.- Chapter 4 Neuroplasticity and its possible role in infectious pathology.- Chapter 4 General principles of morphological diagnostics of infectious pathology in the brain and terminology.- Chapter 5 Acute viral encephalitis.- Chapter 6 Brain lesions in generalized viral infections.- Chapter 7 Viral lesions in HIV infection.- Chapter 8 Meningococcal infection.- Chapter 9 Purulent meningitis and meningoencephalitis.- Chapter 10 Brain abscesses.- Chapter 11  Neurotuberculosis and neurosyphilis.- Chapter 12 Lesions due to fungi, protozoa and helminthes.- Chapter 13 “Slow” neuroinfections.- Chapter 14 Brain lesions in perinatal infections.- Chapter 15 Postraumatic encephalitis.- Chapter 16 Differential diagnostics in clinical pathology.- Chapter 17 Probable role of biological pathogens in noninfectious pathology.- Conclusion.