Pancreatic Cancer: A Multidisciplinary Approach

Manoop S. Bhutani,MD FASGE,FACG,FACP,AGAFWalter H Wriston Distinguished Professor for Pancreatic Cancer ResearchDirector of Endoscopic Research & DevelopmentDept. of Gastroenterology,Hepatology and NutritionUT MD Anderson Cancer Center, Houston,TX,USA Matthew H.G. Katz, MD, FACSLockton Distinguished Chair in Pancreatic Cancer ResearchProfessor and ChairDepartment of Surgical OncologyThe University of Texas MD Anderson Cancer CenterHouston, TXUSAAnirban Maitra, MDScientific Director, Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer ResearchProfessor, Department of Pathology and Translational Molecular PathologyUniversity of Texas MD Anderson Cancer CenterHouston, TXUSA Joseph Herman MD, MSc, MSHCM*Director of Clinical ResearchProfessor, Zucker School of Medicine at Hofstra/NorthwellVice Chair of Informatics, Department of Radiation OncologyNorthwell Health Cancer InstituteNew Hyde Park, NYUSA*Previously at UT MD Anderson Cancer Center at the time of conception of this work.  Robert A. Wolff, MDSheikh Zayed Bin Sultan Al Nahyan Distinguished University Chair of Medical OncologyProfessor, Department of Gastrointestinal Medical Oncology University of Texas MD Anderson Cancer CenterHouston, TXUSA

• Pancreatic Cancer at a Glance.- Risk Factors and Genetic Predisposition.- Pancreatic Cancer and Diabetes Mellitus.- Pancreatic Cancer Screening.- Diagnosis and Staging of Pancreatic Cancer.- Imaging Evaluations: Pancreatic Protocol CT and MRI, PET-CT.- Laparoscopy.- Role of Gastroenterologists: Endoscopic Ultrasound (EUS), EUS-guided Biopsy.- Role of Ca 19-9 in Diagnosis/Staging and Management.- Management of Locally Advanced/ Metastatic Disease.- Medical Oncology.- Radiation Oncology.- Management of Resectable and Borderline Resectable Disease.- Surgery.- Medical Oncology.- Radiation Oncology.- Endoscopic Management of Pancreatic Cancer Symptoms.- Jaundice/Biliary Obstruction: ERCP/EUS BD.- Gastric Outlet Obstruction: Antroduodenal Stenting, Venting PEG, EUS-guided Gastrojejunostomy.- Pain Control: Celiac Plexus Neurolysis.- Emerging Paradigms in Pancreatic Cancer.- Minimally Invasive Surgical Approaches.- EUS-Guided Local Therapies.- Imaging Based Biomarkers for Pancreatic Cancer.- Liquid Biopsies in Pancreatic Cancer.- Molecular Profiling and Precision Medicine for Pancreatic Cancer.- The Prospects of Immunotherapy in Pancreatic Cancer.- Microbiome in Pancreatic Cancer.- Early Drug Development in Pancreatic Cancer.- Mechanisms and Evidence on Pancreatic Cancer Prevention.- Nutrition in Pancreatic Cancer.- Prioritizing the Patient Experience: Early Integration of Supportive/Palliative Care in Pancreatic Cancer Management.- Patient Reported Outcomes and Quality of Life.- Alternative/Integrative Medicine in Pancreatic Cancer.