Icro Maremmani, was born in Pietrasanta (Lucca) on May 18th, 1951. He graduated in Medicine at Pisa University in 1979, becoming a specialist in Psychiatry cum laude there in 1983. In 2014 he was officially recognised as a qualified Full Professor of Psychiatry. He has been professor of Addiction Medicine at Pisa University since 1994 and at the Saint Camillus International University of Health Sciences in Rome since 2020. His main field of interest is opioid agonist treatment of opioid use disorder patients, especially in dual disorder patients. He has been a collaborator of the American Association for the treatment of Opioid Dependence (AATOD) since 1988 (working on its Executive Committee); the Italian Society of Addiction Medicine (SITD) since 1990 (co-founder and past President); the European Opiate Addiction Treatment Association (EUROPAD) since 1994 (co-founder and President from its foundation). He is President of the World Federation for the Treatment of Opioid Dependence (WFTOD), a non-governmental organisation recognised by the ECOSOC of the United Nations and in 2022 founded its department, - “Addiction Research Methods Institute”- in New York, NY, USA. The same year, he founded the PISA-School of Addiction Medicine at the De Lisio Institute of Behavioural Sciences in Pisa, Italy. He is a founding-member and vice-president of the World Association of Dual Disorders (WADD). He was the first non-American to be awarded the Dole and Nyswander prize, in Washington DC, in 1994. He was given the Chimera career award in 2004 in Paris and became an honorary member of the Spanish Society of Dual Pathology (SEPD) in 2015 in Barcelona. In 2016, in Montreal, he was recognised as an ISAM (International Society of Addiction Medicine) fellow (FISAM). He presented the Dole & Nyswander Award in 2019 in Orlando, FL, USA. He has published scientific papers in Italian (totalling over 400) and English (over 300). He has actively participated in more than 500 scientific seminars and congresses. He is Editor-in-Chief of Heroin Addiction and Related Clinical Problems, the Journal of Clinical Medicine (Section of Psychiatry), and the Italian Journal of the Addictions. He is a member of the editorial board of the International Journal of Environmental Research and Public Health and Frontiers in Psychiatry. He lives and works in Pietrasanta.Angelo Giovanni Icro Maremmani was born in Pietrasanta (Lucca) on April 21st, 1984. He graduated in Medicine at Pisa University in 2009 and became a specialist in Psychiatry cum laude again in Pisa in 2015. He graduated from the Doctorate Programme in Biochemistry and Molecular Biology at Siena University in 2020. In 2017 he was officially recognised as possessing all the credentials required to become an Associate Professor of Psychiatry. He has been teaching Addiction Medicine at Pisa University since 2013. He is a Professor of Addiction Medicine at the Saint Camillus International University of Health Sciences in Rome. He received the Chimera Award in Grenoble, France, in 2021. His field of interest is Addiction Medicine, particularly regarding opioid addiction and dual-disorder patients. He is a member of AU-CNS and is an active collaborator of EUROPAD and WFTOD. He is President of the Pisa School of Clinical and Experimental Psychiatry, founded in 2017 and a PISA-School of Addiction Medicine teacher member. He was a fellow at British Columbia University (Vancouver, Canada) in the spring and summer of 2014 and at Rockefeller University (NY, USA) in the fall of 2014. He has worked as a physician in charge at ASL Toscana Nord Occidentale (Versilia, North-Western Tuscany) since 2016. He has published papers in Italian (over 20) and English (over 90) and has actively contributed to more than 20 congresses and seminars. He is the Associate Director of Frontiers in Psychiatry, Addictive Disorders section, and is a member of the editorial board of Heroin Addiction and Related Clinical Problems. He lives in Marina di Pietrasanta and works in Viareggio.Matteo Pacini was born in Pisa on January 24th, 1975. He graduated in Medicine at Pisa University cum laude in 1999 and specialised in Psychiatry there in 2003. He has been professor of Addiction Medicine in university post-graduate courses since 2011. He is a Professor of Addiction Medicine at the Saint Camillus International University of Health Sciences in Rome and a PISA-School of Addiction Medicine teaching member. His fields of interest are Addiction Medicine, Forensic Psychiatry and Dual Disorders. He collaborates with Europad, representing Italy on its international scientific committee. He received the Europad Chimera career award in Krakow in 2018 and won research prizes for one paper about QT prolongation during methadone maintenance (Europad, Pietrasanta, 2001) and then for another one on the long-term outcome of dual diagnosis heroin addicts in agonist treatment (SOPSI, Rome, 2002). He has published over 30works in Italian and over 90 in English. He has actively contributed to over 50 congresses and seminars. He is a member of the editorial board of Heroin Addiction and Related Clinical Problems. He lives and works in Pisa.

• 1. Guiding Principles For The Treatment Of Dual Disorder Patients.- 2. Mood Disorders In Dual Disorder Heroin Use Disorder Patients.- 3. Anxiety Disorders In Dual Disorder Heroin Use Disorder Patients.- 4. Chronic Psychosis in Dual Disorder Heroin Use Disorder patients.- 5. Dual disorder special populations. Violent heroin use disorder patients.- 6. Alcohol Use Disorder And Polydrug Use In Heroin Use Disorder Patients.

Icro Maremmani, was born in Pietrasanta (Lucca) on May 18th, 1951. He graduated in Medicine at Pisa University in 1979, becoming a specialist in Psychiatry cum laude there in 1983. In 2014 he was officially recognised as a qualified Full Professor of Psychiatry. He has been professor of Addiction Medicine at Pisa University since 1994 and at the Saint Camillus International University of Health Sciences in Rome since 2020. His main field of interest is opioid agonist treatment of opioid use disorder patients, especially in dual disorder patients. He has been a collaborator of the American Association for the treatment of Opioid Dependence (AATOD) since 1988 (working on its Executive Committee); the Italian Society of Addiction Medicine (SITD) since 1990 (co-founder and past President); the European Opiate Addiction Treatment Association (EUROPAD) since 1994 (co-founder and President from its foundation). He is President of the World Federation for the Treatment of Opioid Dependence (WFTOD), a non-governmental organisation recognised by the ECOSOC of the United Nations and in 2022 founded its department, - “Addiction Research Methods Institute”- in New York, NY, USA. The same year, he founded the PISA-School of Addiction Medicine at the De Lisio Institute of Behavioural Sciences in Pisa, Italy. He is a founding-member and vice-president of the World Association of Dual Disorders (WADD). He was the first non-American to be awarded the Dole and Nyswander prize, in Washington DC, in 1994. He was given the Chimera career award in 2004 in Paris and became an honorary member of the Spanish Society of Dual Pathology (SEPD) in 2015 in Barcelona. In 2016, in Montreal, he was recognised as an ISAM (International Society of Addiction Medicine) fellow (FISAM). He presented the Dole & Nyswander Award in 2019 in Orlando, FL, USA. He has published scientific papers in Italian (totalling over 400) and English (over 300). He has actively participated in more than 500 scientific seminars and congresses. He is Editor-in-Chief of Heroin Addiction and Related Clinical Problems, the Journal of Clinical Medicine (Section of Psychiatry), and the Italian Journal of the Addictions. He is a member of the editorial board of the International Journal of Environmental Research and Public Health and Frontiers in Psychiatry. He lives and works in Pietrasanta.Angelo Giovanni Icro Maremmani was born in Pietrasanta (Lucca) on April 21st, 1984. He graduated in Medicine at Pisa University in 2009 and became a specialist in Psychiatry cum laude again in Pisa in 2015. He graduated from the Doctorate Programme in Biochemistry and Molecular Biology at Siena University in 2020. In 2017 he was officially recognised as possessing all the credentials required to become an Associate Professor of Psychiatry. He has been teaching Addiction Medicine at Pisa University since 2013. He is a Professor of Addiction Medicine at the Saint Camillus International University of Health Sciences in Rome. He received the Chimera Award in Grenoble, France, in 2021. His field of interest is Addiction Medicine, particularly regarding opioid addiction and dual-disorder patients. He is a member of AU-CNS and is an active collaborator of EUROPAD and WFTOD. He is President of the Pisa School of Clinical and Experimental Psychiatry, founded in 2017 and a PISA-School of Addiction Medicine teacher member. He was a fellow at British Columbia University (Vancouver, Canada) in the spring and summer of 2014 and at Rockefeller University (NY, USA) in the fall of 2014. He has worked as a physician in charge at ASL Toscana Nord Occidentale (Versilia, North-Western Tuscany) since 2016. He has published papers in Italian (over 20) and English (over 90) and has actively contributed to more than 20 congresses and seminars. He is the Associate Director of Frontiers in Psychiatry, Addictive Disorders section, and is a member of the editorial board of Heroin Addiction and Related Clinical Problems. He lives in Marina di Pietrasanta and works in Viareggio.Matteo Pacini was born in Pisa on January 24th, 1975. He graduated in Medicine at Pisa University cum laude in 1999 and specialised in Psychiatry there in 2003. He has been professor of Addiction Medicine in university post-graduate courses since 2011. He is a Professor of Addiction Medicine at the Saint Camillus International University of Health Sciences in Rome and a PISA-School of Addiction Medicine teaching member. His fields of interest are Addiction Medicine, Forensic Psychiatry and Dual Disorders. He collaborates with Europad, representing Italy on its international scientific committee. He received the Europad Chimera career award in Krakow in 2018 and won research prizes for one paper about QT prolongation during methadone maintenance (Europad, Pietrasanta, 2001) and then for another one on the long-term outcome of dual diagnosis heroin addicts in agonist treatment (SOPSI, Rome, 2002). He has published over 30works in Italian and over 90 in English. He has actively contributed to over 50 congresses and seminars. He is a member of the editorial board of Heroin Addiction and Related Clinical Problems. He lives and works in Pisa.

• 1. Guiding Principles For The Treatment Of Dual Disorder Patients.- 2. Mood Disorders In Dual Disorder Heroin Use Disorder Patients.- 3. Anxiety Disorders In Dual Disorder Heroin Use Disorder Patients.- 4. Chronic Psychosis in Dual Disorder Heroin Use Disorder patients.- 5. Dual disorder special populations. Violent heroin use disorder patients.- 6. Alcohol Use Disorder And Polydrug Use In Heroin Use Disorder Patients.