Atlas of Renal Ultrastructural Pathology

Dr Candice Roufosse is Senior Clinical Lecturer (Centre for Inflammatory Diseases Imperial College) and Honorary Consultant in Renal and Transplant Cellular Pathology (Subspecialty Lead for Renal and Electron Microscopy) North West London Pathology (affiliated to Imperial College Healthcare NHS Trust). She has been a consultant in Cellular Pathology specialised in renal and transplant pathology for the last 12 years. She is a clinician scientist with a particular interest in translational research in the application of transcript analysis, electron microscopy and novel imaging technologies to renal and transplant diagnosis. She is a trial pathologist involved in several clinical trials in transplantation and glomerulonephritis, both industry and grant-funded.Dr Verena Broecker is a diagnostic histopathologist subspecialised in renal pathology at Sahlgrenska University Hospital in Gothenburg, Sweden. She has been working with renal pathology for 13 years, starting her career inGermany to continue in Great Britain and finally Sweden. She has published mainly in the field of transplant renal pathology with a special interest in diagnostic application of electron microscopy. Her diagnostic work covers native and transplant renal biopsies.

• 1. Introduction.- 2. Technical aspects of EM in kidney and artefacts.- 3. Approach to US examination of Kidney.- 4. Normal kidney structures on EM.- 5. Acquired Glomerular diseases with deposits.- 6. Immune complex, predominantly non-organised glomerular diseases.- 7. Immune complex, predominantly organised glomerular diseases.- 8. Complement, organised and non-organised glomerular diseases.- 9. Light chains only (and amyloid in general).- 10. Acquired Glomerular diseases without deposits.- 11. Vasculitis/anti-GBM.- 12. Podocytopathies.- 13. Matrix.- 14. TMA.- 15. Innate glomerular diseases including storage diseases.- 16. Podocytopathies.- 17. Basement membrane structural abnormalities.- 18. Fabry’s and other storage.- 19. Coll III, Fibronectin.- 20. LCAT-deficiency and other lipoprotein things and other rare pediatric things.- 21. Hypertension.- 22. Tubulo-interstial pathologies.- 23. Acute tubular injury (toxic and ischemic).- 24. Mitochondrial.- 25. Viral infections not related totransplantation.- 26. Genetic including cystic diseases.- 27. Immune complex.- 28. Complement.- 29. Light chain.- 30. Xanthogranulomatous Pyelonephritis: Malakoplakia, rare non-viral infections?.- 31. Anticoagulant- Related Nephropathy.-  32. Heavy Metal Nephropathy (Lead and Cadmium Nephropathy).- 33. Vascular Pathologies.- 34. Arteriolar hyaline.- 35. Immune complexes.- 36. TMA.- 37. Atheroemboli.- 38. Transplantation introduction.- 39. Donor-derived changes.- 40. Recurrent Glom disease.- 41. Diabetic change.- 42. AMR.- 43. Viral infections seen in transplantation.- 44. Cyclosporin/Tacrolimus Nephrotoxicity.