Daniel M. Trifiletti, MD is a Professor of Radiation Oncology at The Mayo Clinic. He has won a number of awards related to his work in radiation oncology and has published extensively. Samuel T. Chao, MD, FASTRO is a Professor in the Department of Radiation Oncology and the Brain Tumor and Neuro-Oncology Center at the Cleveland Clinic. He is also Director of CNS Radiation Oncology, Head of the Center for Cerebral Radiation Necrosis, Associate Director of the Gamma Knife Center, and Vice Chair of Quality and Safety in Radiation Oncology. Arjun Sahgal, MD, FRCPC is an Associate Professor in the Department of Radiation Oncology and Surgery at the University of Toronto. Jason P. Sheehan, MD, PhD is a Professor of Neurological Surgery, Radiation Oncology, Biomedical Engineering and Neuroscience, and the Harrison Distinguished Teaching Chair of Neurosurgery at The University of Virginia, Health Sciences Center. There he is also the Neuroscience and Behavioral Science Medicine Service Line Director, Vice Chair of Academic Affairs in Neurological Surgery, Director of the Lars Leksell Gamma Knife Center, Co-Director of the UVa-Mary Washington Radiosurgery Center, Associate Residency Program Director, Director of Spinal Radiosurgery, and Co-medical Director of the UVa-Riverside Radiosurgery Center. He has published extensively in radiation oncology.

“This is the second edition of this book and a warranted update with the technological advances and expansion in use of delivery of stereotactic body radiation therapy (SBRT) worldwide. … each chapter has comprehensive references to the latest literature from around the world and a nice summary at the end. … This is a very comprehensive text on SBRT that will be a useful resource to both new and existing practitioners in the field.” (Ruth McLauchlan, RAD Magazine, December, 2024)

• Part I: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy.- Vascular-Mediated Mechanisms and SRS/SBRT.- Radio-Immunology of Ablative Radiation.- Rationale for Fractionated SRS and Single SRS Session Approaches.- Part II: Intracranial Radiosurgery Technique.- Physics of Radiosurgery.- Leksell Gamma Knife Radiosurgery.- CyberKnife Robotic Stereotactic Radiosurgery.- Linear Accelerator-Based Radiosurgery: Technique.- Fractionated Radiosurgery.- Charged-Particle Proton Radiosurgery.- Part III: Intracranial Radiosurgery by Indication.- Stereotactic Radiosurgery for Brain Metastases.- Stereotactic Radiosurgery for Pituitary Adenoma.- Stereotactic Radiosurgery for Meningioma.- Stereotactic Radiosurgery for Intracranial Arteriovenous Malformations.- Radiosurgical Management of Trigeminal Neuralgia.- Radiosurgery for Vestibular Schwannomas.- Stereotactic Radiosurgery for Glial Tumors.- Part IV: Stereotactic Body Radiation Therapy Technique.- Physics of Stereotactic Body Radiotherapy.- Immobilization for SBRT: A Crucial Prerequisite Toward Accurate Treatment.- Motion Management in Stereotactic Body Radiation Therapy.- Charged Particle Stereotactic Body Radiation Therapy.- Part V: Stereotactic Body Radiation Therapy by Indication.- Stereotactic Body Radiation Therapy (SBRT) for Primary Lung Cancer.- Stereotactic Body Radiation Therapy (SBRT) for Lung Metastases.- Stereotactic Body Radiation Therapy (SBRT) for Spinal Tumors.- Stereotactic Body Radiation Therapy for Gastrointestinal Cancers.- SAbR for Primary Prostate Cancer.- Stereotactic Ablative Radiotherapy (SAbR) for Primary Renal Cell Carcinoma.- Head and Neck Stereotactic Body Radiation Therapy.- Pediatric Radiosurgery.- Part VI: The Future of Radiosurgery and SBRT.- Patient Selection in SBRT and SRS.- SRS and SBRT Complications and Management.- SRS and SBRT Integration with Supportive Care.- Targeted Agents and Immunotherapy.- Diagnostic Imaging Advances.- Part VII: The Future of Radiosurgery and SBRT.- Comparative Effectiveness of SBRT.

Daniel M. Trifiletti, MD is a Professor of Radiation Oncology at The Mayo Clinic. He has won a number of awards related to his work in radiation oncology and has published extensively. Samuel T. Chao, MD, FASTRO is a Professor in the Department of Radiation Oncology and the Brain Tumor and Neuro-Oncology Center at the Cleveland Clinic. He is also Director of CNS Radiation Oncology, Head of the Center for Cerebral Radiation Necrosis, Associate Director of the Gamma Knife Center, and Vice Chair of Quality and Safety in Radiation Oncology. Arjun Sahgal, MD, FRCPC is an Associate Professor in the Department of Radiation Oncology and Surgery at the University of Toronto. Jason P. Sheehan, MD, PhD is a Professor of Neurological Surgery, Radiation Oncology, Biomedical Engineering and Neuroscience, and the Harrison Distinguished Teaching Chair of Neurosurgery at The University of Virginia, Health Sciences Center. There he is also the Neuroscience and Behavioral Science Medicine Service Line Director, Vice Chair of Academic Affairs in Neurological Surgery, Director of the Lars Leksell Gamma Knife Center, Co-Director of the UVa-Mary Washington Radiosurgery Center, Associate Residency Program Director, Director of Spinal Radiosurgery, and Co-medical Director of the UVa-Riverside Radiosurgery Center. He has published extensively in radiation oncology.

“This is the second edition of this book and a warranted update with the technological advances and expansion in use of delivery of stereotactic body radiation therapy (SBRT) worldwide. … each chapter has comprehensive references to the latest literature from around the world and a nice summary at the end. … This is a very comprehensive text on SBRT that will be a useful resource to both new and existing practitioners in the field.” (Ruth McLauchlan, RAD Magazine, December, 2024)

• Part I: Radiobiology of Radiosurgery and Stereotactic Body Radiation Therapy.- Vascular-Mediated Mechanisms and SRS/SBRT.- Radio-Immunology of Ablative Radiation.- Rationale for Fractionated SRS and Single SRS Session Approaches.- Part II: Intracranial Radiosurgery Technique.- Physics of Radiosurgery.- Leksell Gamma Knife Radiosurgery.- CyberKnife Robotic Stereotactic Radiosurgery.- Linear Accelerator-Based Radiosurgery: Technique.- Fractionated Radiosurgery.- Charged-Particle Proton Radiosurgery.- Part III: Intracranial Radiosurgery by Indication.- Stereotactic Radiosurgery for Brain Metastases.- Stereotactic Radiosurgery for Pituitary Adenoma.- Stereotactic Radiosurgery for Meningioma.- Stereotactic Radiosurgery for Intracranial Arteriovenous Malformations.- Radiosurgical Management of Trigeminal Neuralgia.- Radiosurgery for Vestibular Schwannomas.- Stereotactic Radiosurgery for Glial Tumors.- Part IV: Stereotactic Body Radiation Therapy Technique.- Physics of Stereotactic Body Radiotherapy.- Immobilization for SBRT: A Crucial Prerequisite Toward Accurate Treatment.- Motion Management in Stereotactic Body Radiation Therapy.- Charged Particle Stereotactic Body Radiation Therapy.- Part V: Stereotactic Body Radiation Therapy by Indication.- Stereotactic Body Radiation Therapy (SBRT) for Primary Lung Cancer.- Stereotactic Body Radiation Therapy (SBRT) for Lung Metastases.- Stereotactic Body Radiation Therapy (SBRT) for Spinal Tumors.- Stereotactic Body Radiation Therapy for Gastrointestinal Cancers.- SAbR for Primary Prostate Cancer.- Stereotactic Ablative Radiotherapy (SAbR) for Primary Renal Cell Carcinoma.- Head and Neck Stereotactic Body Radiation Therapy.- Pediatric Radiosurgery.- Part VI: The Future of Radiosurgery and SBRT.- Patient Selection in SBRT and SRS.- SRS and SBRT Complications and Management.- SRS and SBRT Integration with Supportive Care.- Targeted Agents and Immunotherapy.- Diagnostic Imaging Advances.- Part VII: The Future of Radiosurgery and SBRT.- Comparative Effectiveness of SBRT.