The CCIS book constitutes selected papers accepted in the Research Track on Artificial Intelligence of the 11th International Conference on Computational Science and Computational Intelligence, CSCI 2024, which took place in Las Vegas, NV, USA, during December 11–13, 2024.The 25 full papers included in this book were carefully reviewed and selected from a total of 383 submissions. They were organized in topical sections on machine learning, neural networks, knowledge graphs, and applications; artificial intelligence and novel applications; and computational intelligence and applications.