This book constitutes the refereed post-conference proceedings of the 8th EAI International Conference on Innovations and Interdisciplinary Solutions for Underserved Areas, InterSol 2025, held in Ouagadougou, Burkina Faso, during July 3–4, 2025.The 19 full papers and 3 short papers included in this book were carefully reviewed and selected from 110 submissions.They were organized in topical sections as follows: Artificial Intelligence and Applications; Networks, Security, Blockchain and Applications; Information and Communication Technology; and Short Papers.