Pineal Tumors and Pineal Region Tumors

Carmine Mottolese was born in Naples and attended the Medical Faculty of Medicine Federico II In this town. He graduated with 110/110 cum laude in 1977; admitted to the Neurosurgery residency program in the same year he obtained his qualification in 1981. He then moved to Lyon as Foreign Resident in the service of Neurosurgery of the Civil Hospital, directed by the Pr. Claude Lapras. In July 1985 he was appointed senior neurosurgeon in the Neurosurgical Service of the “Pierre Wertheimer “Hospital, where he became Head of the Pediatric Service in 2000 (until 2021).Since 2000 he has collaborated with the Marc Jeannerot Neurocognitive Institute of Lyon working on the “Functional mapping of the cerebellum”. He still holds a position in the same Institute as an associate researcher, and collaborates with the Dept. of Pediatric Neurosurgery, Hopital Femme Mère Enfant, Hospices Civils de Lyon. He was founder member of the French Pediatric Neurosurgical Society,President of the French Pediatric Neurosurgical Society andCommendator of the Palmes Academic of the Minister of National Education.

• 1. History of pineal tumors and their treatment.- 2. Incidence of pineal tumors.- 3. Anatomy and microsurgical anatomy of the pineal region.- 4. Melatonin: some aspects of biochemistry, physiology and pharmacology.- 5. Pineal region tumors: Clinical symptoms and syndromes.- 6. Imaging of Pineal Region Masses.- 7. Histopathology and molecular pathology of pineal region tumors.- 8. Pineal tumors, the decisional tree in children and adults.- 9. Hydrocephalus Secondary to Pineal Region Lesions.- 10. Biopsy of pineal tumors: endoscopy or stereotaxic or neuronavigation guided?.- 11. Surgery of pineal and pineal region tumors: The sub-occipital transtentorial approach for pineal tumors. How we do it in lyon.- 12. The infra tentorial supracerebellar approach: the most used avenue for pineal and pineal region tumors. How we do it.- 13.  Surgery of pineal and pineal region tumors:  Alternatives approaches to pineal tumors. How to do it.- 14. Pineal Cysts: Clinical Insights and Management Strategies.- 15. Germinomas and non germinomatous germ cell tumors.- 16. Radiotherapy for pineal region tumors.- 17. Pineal tumours: results, follow-up and sequels in children and adults according the French Register of pineal tumours and the Lyonnais Register.- 18. The pinealoprive syndrome: myth or reality?.- 19. Conclusions.