Neurokirurgi

Lars Leksell Neurokirurgen Innovatören Humanisten

Lars Leksell (1907-1986) var en framgångsrik neurokirurg, forskare, professor, innovatör och humanist. Han ägnade en stor del av sitt innehållsrika och idoga liv åt sin profession men hade även ett rikt och spännande privatliv. Som engagerad och framstående medicinare nådde han internationell framgång och berömmelse. I fokus för hans uppmärksamhet låg utvecklandet av nya behandlingsmetoder vid sjukdomar i nervsystemet. Genom detta intresse blev han också en uppfinnare och konstruktör av en rad specialinstrument som används runt om i världen. Hans dröm om den "oblodiga operationen" kom att resultera i den mest kända innovationen - Gammakniven.

"Han var en 1900-talsmänniska. Hos honom möter vi flera av seklets stora förändringsprocesser i liv och tanke," skriver bokens författare. De tecknar Leksells liv och karriär, hans långa och framgångsrika men inte okontroversiella yrkesbana, hans styrka och orädda debattvillighet. Leksell var en stark personlighet och inte rädd att framstå som obekväm. HJÄRNOR OCH HJÄRTAN är ett porträtt i helfigur, en biografi om en människa av kött och blod, med styrkor och svagheter, av motsägelser och engagemang. Leksell var inte enbart en berömd neurokirurg utan också en kulturälskande humanist. Boken är rikt illustrerad.

Åsa och Tommy Bergenheim, båda professor emeritus/emerita, har utifrån sina olika perspektiv tillsammans skildrat en av förra århundradets internationellt sett stora neurokirurger, forskaren och innovatören, professor Lars Leksell. Kombinationen av författarnas historiska och medicinska kompetens ger HJÄRNOR OCH HJÄRTAN en särskild tyngd och gör den samtidigt tillgänglig för en bred läsekrets. Författarna är sedan många år gifta med varandra, har en stor familj och bor i Umeå.

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"Boken är en fängslande läsning för både hjärna och hjärta och lämnar ingen oberörd." Per Almqvist, Läkartidningen

"Den torrt tekniska prosan om hjärnans anatomi borde egentligen inte erbjuda någon rafflande läsning, men det var länge sedan jag var så här uppslukad av en populärvetenskaplig bok.​ /.../ Snarare än att förenkla det komplexa till varje pris är det en bok som bjuder in läsaren till en annan värld.​"

​Erik Isberg, Expressen

"Sjöbergs berättelser försätter läsaren i det där åtråvärda lästillståndet när världen utanför grumlas och såväl tid som rum förefaller mindre avtecknade – inte helt olikt det tillstånd som Sjöberg själv verkar befinna sig i under operationerna."

Johan Bengtsson​, Läkartidningen

Vad är vårt jag uppbyggt av? Våra minnen? Och den fria viljan – finns den? Om den finns, kan man med ett kirurgiskt ingrepp operera bort den? Rickard Sjöberg är överläkare och docent i neurokirurgi men också docent i medicinsk psykologi och har därmed en mycket mångsidig och unik form av expertis om hjärnan. I Hjärnan och jaget använder han den för att ta oss med i vindlande och svindlande resonemang kring människans essens. Utifrån operationer av olika delar av hjärnan berättar han om detta ofattbara organ och ställer frågor som får oss att förundras över allt det som människan är – och var i oss det egentligen kan hittas.

Författaren skriver: "Varje operation är ett unikt utsnitt i tiden med en början och ett slut. Den har därmed berättelsens struktur. Alla kirurger dokumenterar också nogsamt så kallade operationsberättelser som återger dessa förlopp. Här kommenteras de praktiska frågorna. Djupare reflektioner kring själsliga funktioner lyser dock ofta med sin frånvaro. Men ibland har det hänt att jag tänkt att det skulle vara roligt att utvidga de här berättelserna så att de kom att omfatta även de existentiella frågorna på ett sätt som skulle kunna vara tillgängligt även för personer som inte är kirurger."

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THE INSIDER’S GUIDE TO ACING THE NEUROLOGY BOARD EXAM – WRITTEN BY PHYSICIANS WHO PASSED

Apply the proven First Aid formula for exam success!

Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair.

Image-Guided Neurosurgery provides readers with an update on the revolutionary improvements in imaging and visualization relating to neurosurgery. From the development of the pneumoencephalogram, to the operating microscope, to cross sectional imaging with CT and later MRI, to stereotaxy and neuronavigation, the ability to visualize the pathology and surrounding neural structures has been the driving factor leading surgical innovation and improved outcomes.

The book provides a comprehensive reference on the application of contemporary imaging technologies used in neurosurgery. Specific techniques discussed include brain biopsies, brain tumor resection, deep brain stimulation, and more.

The book is ideal for neurosurgeons, interventional radiologists, neurologists, psychiatrists, and radiologists, as well as technical experts in imaging, image analysis, computer science, and biomedical engineering.

New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury.

This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury.

Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems.

Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients.

Neurosurgical Neuropsychology: The Practical Application of Neuropsychology in the Neurosurgical Practice comprehensively explains the use of neuropsychology in neurosurgical settings. The book covers various preoperative techniques that may benefit neurosurgeons, such as functional neuroimaging (fMRI, SPECT, MEG) for presurgical cognitive mapping, as well as more traditional methods to predict outcomes after surgery, including neurocognitive testing and the Wada procedure. The book's editors discuss why neuropsychologists add considerable value to the neurosurgical team. A wide range of patient populations are covered, ranging from Deep Brain Stimulation candidates for Parkinson's disease, to adult and pediatric epilepsy candidates and neuro-oncology cases.

This book is ideal for neurosurgeons, neuropsychologists, neuro-oncologists, epileptologists, general neurologists, and others who want to know more about the use of neuropsychology as a tool in the presurgical and postoperative phases of neurosurgery.

Intracranial Epidural Bleeding: History, Management, and Pathophysiology examines the history of the concepts underlying the understanding of the clinical features of epidural bleeding. The pathophysiology of epidural bleeding was examined in two PhD theses in the 1980s, with the results published in top international journals. However, these concepts have not been understood by the general neurosurgical community. This book provides a comprehensive overview of how epidural bleeding actually works. It can be used to help improve the interpretation of images during management, and to assess degrees of urgency. This book is written for neurosurgeons, neurologists, cerebrovascular physiologists, trauma surgeons, and medical historians.

Quality and Safety in Neurosurgery covers recent improvements and presents solutions for problems that impact patient care. This book is written for anyone who works at the intersection of quality, safety and neurosurgery, including neurosurgeons, neurologists, clinical researchers looking to improve outcomes in neurosurgery, hospital quality and safety officers, department leaders, fellows and residents. Edited by neurosurgeons who helped build the culture of quality and safety in the Department of Neurosurgery at UMN, this work emphasizes quality and safety, whether through 'value based purchasing', finding specialty specific quality and safety metrics, or just the professional desire to provide quality care.

Over the last 18 years, there have been many advances in the field of intraoperative monitoring. This new edition of Neurophysiology in Neurosurgery: A Modern Approach provides updates on the original techniques, as well as other more recent methodologies that may either prove beneficial or are commonly used in neuromonitoring. The purpose of this book is to describe the integration of neuromonitoring with surgical procedures. Each methodology is discussed in detail as well as chapters describing how those methodologies are applied to multiple surgical procedures and the evidence used to support those uses.

The second edition features a surgical procedure section, which focuses on specific surgical procedures and the type of monitoring used during these procedures. The original chapters have been updated, expanded, and the structure modified to ensure the book is beneficial to both physiologists and surgeons. This book is written for neurosurgeons, neurophysiologists, neurologists, anesthesiologists, interventional neuroradiologists, orthopedic surgeons, and plastic surgeons.

Spinal Cord Injury Pain presents the basis for preclinical and clinical investigations, along with strategies for new approaches in the treatment of central neuropathic pain. Contributors from the private sector and academia provide a comprehensive review of state-of-the-art research in this challenging space. Topics include Epidemiology of Chronic Pain Following SCI, experimental models and mechanisms of chronic pain in SCI, and new targets and technologies. This book serves as a resource for continued translational research that will result in novel approaches and treatments that improve function and quality of life for individuals with CNP/SCI.

Despite a better understanding of the complexity of mechanisms of CNP/SCI, improved medical and surgical management of SCI, and the subsequent acceleration of the identification of new targets and the development of novel analgesics, there is still a great unmet clinical need in the area of CNP following SCI. Hence, this book is a welcomed addition to current research and developments.