Yasin Temel is a Professor of Neurosurgery, Medical Center in Maastricht University, Maastricht, The Netherlands. Research Director Abdelhamid Benazzouz works in the Neurodegenerative Dis Institute, Bordeaux University, France. Experienced academic researcher with a demonstrated history of working in the field of Neuromodulation and Neurodegenerative disorders. Head of functional neurosurgery section at the department of neurosurgery. Skilled in Fundamental Neuromodulation research and academic teaching, Neuroanatomy, Animal Models, Electrophysiology, Behavior, Stereology and Microscopy. Co-founder and coordinator of Neuromodulation Master Specialization at Maastricht University.

• Part 1: Bench1. The quest for a target and the beginning of the DBS-story2. Early clinical application3. Development of experimental models for movements disorders4. Development of experimental models for psychiatric disordersPart 2: Science behind the clinical application5. Parkinson’s disease6. Dystonia7. Essential tremor8. Epilepsy9. OCD10. Tourette Syndrome11. Depression12. Alzheimer’s disease13. Other indicationsPart 3: Mechanisms of action14. Neurophysiological mechanisms15. Cellular mechanisms16. Metabolic mechanisms17. Neurochemical mechanisms18. Mechanisms investigated by imagingPart 4. Future/perspectives

Yasin Temel is a Professor of Neurosurgery, Medical Center in Maastricht University, Maastricht, The Netherlands. Research Director Abdelhamid Benazzouz works in the Neurodegenerative Dis Institute, Bordeaux University, France. Experienced academic researcher with a demonstrated history of working in the field of Neuromodulation and Neurodegenerative disorders. Head of functional neurosurgery section at the department of neurosurgery. Skilled in Fundamental Neuromodulation research and academic teaching, Neuroanatomy, Animal Models, Electrophysiology, Behavior, Stereology and Microscopy. Co-founder and coordinator of Neuromodulation Master Specialization at Maastricht University.

• Part 1: Bench1. The quest for a target and the beginning of the DBS-story2. Early clinical application3. Development of experimental models for movements disorders4. Development of experimental models for psychiatric disordersPart 2: Science behind the clinical application5. Parkinson’s disease6. Dystonia7. Essential tremor8. Epilepsy9. OCD10. Tourette Syndrome11. Depression12. Alzheimer’s disease13. Other indicationsPart 3: Mechanisms of action14. Neurophysiological mechanisms15. Cellular mechanisms16. Metabolic mechanisms17. Neurochemical mechanisms18. Mechanisms investigated by imagingPart 4. Future/perspectives

Yasin Temel is a Professor of Neurosurgery, Medical Center in Maastricht University, Maastricht, The Netherlands. Research Director Abdelhamid Benazzouz works in the Neurodegenerative Dis Institute, Bordeaux University, France. Experienced academic researcher with a demonstrated history of working in the field of Neuromodulation and Neurodegenerative disorders. Head of functional neurosurgery section at the department of neurosurgery. Skilled in Fundamental Neuromodulation research and academic teaching, Neuroanatomy, Animal Models, Electrophysiology, Behavior, Stereology and Microscopy. Co-founder and coordinator of Neuromodulation Master Specialization at Maastricht University.

• Part 1: Bench1. The quest for a target and the beginning of the DBS-story2. Early clinical application3. Development of experimental models for movements disorders4. Development of experimental models for psychiatric disordersPart 2: Science behind the clinical application5. Parkinson’s disease6. Dystonia7. Essential tremor8. Epilepsy9. OCD10. Tourette Syndrome11. Depression12. Alzheimer’s disease13. Other indicationsPart 3: Mechanisms of action14. Neurophysiological mechanisms15. Cellular mechanisms16. Metabolic mechanisms17. Neurochemical mechanisms18. Mechanisms investigated by imagingPart 4. Future/perspectives