S. David Hudnall, MDProfessor of Pathology and Laboratory MedicineDirector, Hematopathology ProgramAssociate Medical Director, Precipio Diagnostics, LLCYale University School of Medicine310 Cedar StreetNew Haven, CT 06520USADr. Ralf KüppersUniversity of Duisburg-EssenDepartment of Molecular GeneticsInstitute of Cell BiologyHufelandstr. 5545122 EssenGermany

• Introduction.- Clinical features.- Histopathology of Hodgkin lymphoma and closely related lymphomas.- Pathogenesis and molecular genetics of classical Hodgkin lymphoma.- The microenvironment in classical Hodgkin lymphoma.- Role of EBV in classical Hodgkin lymphoma.- Pathobiology of nodular lymphocyte predominant Hodgkin lymphoma.- Composite lymphomas and the relationship of Hodgkin lymphoma to Non-Hodgkin lymphomas.- Epidemiology and genetic risk factors.- Treatment and Prognosis.- Development of targeted therapies.

S. David Hudnall, MDProfessor of Pathology and Laboratory MedicineDirector, Hematopathology ProgramAssociate Medical Director, Precipio Diagnostics, LLCYale University School of Medicine310 Cedar StreetNew Haven, CT 06520USADr. Ralf KüppersUniversity of Duisburg-EssenDepartment of Molecular GeneticsInstitute of Cell BiologyHufelandstr. 5545122 EssenGermany

• Introduction.- Clinical features.- Histopathology of Hodgkin lymphoma and closely related lymphomas.- Pathogenesis and molecular genetics of classical Hodgkin lymphoma.- The microenvironment in classical Hodgkin lymphoma.- Role of EBV in classical Hodgkin lymphoma.- Pathobiology of nodular lymphocyte predominant Hodgkin lymphoma.- Composite lymphomas and the relationship of Hodgkin lymphoma to Non-Hodgkin lymphomas.- Epidemiology and genetic risk factors.- Treatment and Prognosis.- Development of targeted therapies.

S. David Hudnall, MDProfessor of Pathology and Laboratory MedicineDirector, Hematopathology ProgramAssociate Medical Director, Precipio Diagnostics, LLCYale University School of Medicine310 Cedar StreetNew Haven, CT 06520USADr. Ralf KüppersUniversity of Duisburg-EssenDepartment of Molecular GeneticsInstitute of Cell BiologyHufelandstr. 5545122 EssenGermany

• Introduction.- Clinical features.- Histopathology of Hodgkin lymphoma and closely related lymphomas.- Pathogenesis and molecular genetics of classical Hodgkin lymphoma.- The microenvironment in classical Hodgkin lymphoma.- Role of EBV in classical Hodgkin lymphoma.- Pathobiology of nodular lymphocyte predominant Hodgkin lymphoma.- Composite lymphomas and the relationship of Hodgkin lymphoma to Non-Hodgkin lymphomas.- Epidemiology and genetic risk factors.- Treatment and Prognosis.- Development of targeted therapies.