This e-book deals with the intersection between religion, philosophy, and politics in the Graeco-Roman world, and especially in Late Antiquity, with special reference to the figure alluded to in ancient sources with the expression "e;theios aner"e;. Charisma and leadership are basic elements of this notion: its literary, historical, and ideological context and the different interpretations of holiness and sanctity in a sociopolitical or educative community are researched in this collective endeavour. The scholarly contributions are organized along three sections - 'Holiness', 'Charisma and Leadership', and 'Transmission and Reception'- aiming at an overall analysis of the patterns involving charismatic leadership of the intellectual and spiritual figures in the sources and its socio-political context, with the central axis of Late Antiquity. Thus, together with some methodological considerations, this e-book examines some well-known figures of holiness and attempts to offer a panoramic, transdisciplinary, and comparative view of their cultural and intellectual context, and to determine what socio-political role they had.