NF-kB in Health and Disease

Inbunden, Engelska, 2011

Del 349 i serien Current Topics in Microbiology and Immunology

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Beskrivning

Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology—from immunity and inflammation to apoptosis, cell survival, growth, and proliferation

Produktinformation

Utgivningsdatum:2011-05-06
Mått:155 x 235 x 20 mm
Vikt:582 g
Format:Inbunden
Språk:Engelska
Serie:Current Topics in Microbiology and Immunology
Antal sidor:268
Upplaga:2011
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783642160165

Utforska kategorier

Onkologi inom Medicin

Innehållsförteckning

Preface.- Understanding the Logic of IkappaB:NF-kappaB Regulation in Structural Terms.- IKK regulation and human genetics.- Specialized chromatin patterns in the control of inflammatory gene expression.- Macrophages and NF-kappaB in Cancer.- NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster.- IKK and NF-kappaB mediated functions in carcinogenesis.- Control of NF-kappaB activity by proteolysis.- NF-kappaB as a target for oncogenic viruses.- NF-kappaB and Innate Immunity.- Inhibition of NF-kappaB signaling as a strategy in disease therapy.- NF-κB and mucosal homeostasis.- NF-kappaB In liver cancer – the plot thickens.- Subject index.