From the reviews: "This is the latest in a series of works summarizing clinical developments and research in critical care and emergency medicine. ... Senior trainees in any critical discipline and practitioners are the intended audience for this work, which originates from an international group of authors and is edited by a leader in multidisciplinary critical care. ... The topics it covers will be of benefit to practicing intensivists and academicians. ... this is a good summary of applied research in the field." (David J. Dries, Doody's Review Service, October, 2012)

• Mechanisms of Multiple Organ Failure.- Coagulation System.- Acute Respiratory Failure.- Endotracheal Intubation.- Ventilator Issues.- Cardiac Crises.- Renal Aspects.- Fluids.- The Microcirculation.- Cardiovascular Monitoring.- Perioperative Medicine.- Infection and Sepsis.- Liver Failure.- Trauma and Emergency Medicine.- Neurological .- Metabolic Disorders and Nutrition.- ICU Organization and Management.- The Future.