• Fri frakt över 249 kr
  • •
  • Snabba leveranser
  • •
  • Billiga böcker
Kundservice

Du är på sajten för privatpersoner.

Företag, bibliotek eller offentlig verksamhet?

Du handlar på classic.bokus.com, där alla dina funktioner finns intakta.
Till classic.bokus.com
Bokus logotyp. Gå till startsidan.
  • Erbjudanden
  • Nyheter
  • Student
  • Topplistor
  • Barn & ungdom
  • Bokus Play
  • E-böcker
  • Pocketböcker
  • Spel & pussel

Upp till 20% på populära nyheter →

Sidfot

Mina sidor

    Hjälp

    • Kundservice
    • Vanliga frågor och svar
    • Frakt och leverans
    • Retur vid ångerrätt
    • Reklamera vara
    • Betalning
    • Köpvillkor
    • Allmänna villkor
    • Information om webbplatsens tillgänglighet

    Om Bokus

    • Om oss
    • Pressrum
    • För studenter
    • För företag
    • För bibliotek och offentlig verksamhet
    • För leverantörer
    • Hållbarhet

    Populärt

    • Aktuella erbjudanden
    • Presentkort
    • Studentlitteratur
    • Nya böcker
    • Topplistor
    • Signerade böcker
    • Engelska böcker

    Inspiration

    • Boktips
    • BookTok
    • Populära bokserier
    • Barnbokskaraktärer
    • Populära författare

    Mina sidor

      Hjälp

      • Kundservice
      • Vanliga frågor och svar
      • Frakt och leverans
      • Retur vid ångerrätt
      • Reklamera vara
      • Betalning
      • Köpvillkor
      • Allmänna villkor
      • Information om webbplatsens tillgänglighet

      Om Bokus

      • Om oss
      • Pressrum
      • För studenter
      • För företag
      • För bibliotek och offentlig verksamhet
      • För leverantörer
      • Hållbarhet

      Populärt

      • Aktuella erbjudanden
      • Presentkort
      • Studentlitteratur
      • Nya böcker
      • Topplistor
      • Signerade böcker
      • Engelska böcker

      Inspiration

      • Boktips
      • BookTok
      • Populära bokserier
      • Barnbokskaraktärer
      • Populära författare
      Logotyp för Bokus
      Följ oss på Facebook (extern länk)Följ oss på Instagram (extern länk)Följ oss på YouTube (extern länk)Följ oss på TikTok (extern länk)
      bokus @ CookiesIntegritetspolicyKöpvillkor
      Till Citymail hemsida (extern länk)Till Budbee hemsida (extern länk)Till Postnord hemsida (extern länk)Till Schenker hemsida (extern länk)Till Early Bird hemsida (extern länk)Till Walleys hemsida (extern länk)
      1. Medicin
      2. Omvårdnad och medicinska stödfunktioner
      3. Apotek och farmaceuter

      General Pharmacology

      AvAlfred J. Clark

      Häftad, Engelska, 1937

      Del i serien Handbuch der Experimentellen Pharmakologie

      1 124 kr

      Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

      Fler format och utgåvor

      E-bok

      732 kr

      Häftad

      566 kr

      Beskrivning

      The author's general aim has been to survey as wide a field of evidence as possible and this had involved excursions into subjects of which he has little first hand knowledge. This width of range also has necessitated a somewhat arbitrary selection of evidence and has prevented full discussion of any indi- vidual problem. The author trusts that he has not misrepresented anyone's results or opinions, and if this has occurred, he can only plead in excuse the peculiar difficulty of giving a brief and yet accurate account of evidence of such a wide variety. The diagrams reproduced in the article have all been redrawn and in many cases the original figures or diagrams have been modified as, for instance, by recalculating dosage on the logarithmic scale. The original authors therefore have no direct responsibility for the diagrams in their present form. The author desires to thank Messrs Arnold and Co. for permitting the repro- duction of Figs. 9 and 23 from similar figures which appeared in his book "The Mode of Action of Drugs on Cells"; portions of other figures from this book also have been reproduced in modified form. The author also desires to thank Dr. J. M.ROBSON for help in correction of the proofs. Edinburgh, July, 1937. A. J. CLARK. Contents.

      Produktinformation

      • Utgivningsdatum:1937-01-01
      • Mått:178 x 254 x undefined mm
      • Vikt:460 g
      • Format:Häftad
      • Språk:Engelska
      • Serie:Handbuch der Experimentellen Pharmakologie
      • Antal sidor:230
      • Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
      • ISBN:9783642896071

      Utforska kategorier

      • Apotek och farmaceuter inom Medicin

      Innehållsförteckning

      • 1: Methods of General Pharmacology.- General Considerations.- Selection of Material.- Employment of Physicochemical Methods.- The Mathematical Interpretation of Biological Data.- Favourable Factors in Pharmacological Measurements.- Curves Relating Exposure to Drugs with Biological Effect.- Classes of Curves.- Discussion.- 2: The Cell as a Physicochemical System.- The Structure of Protoplasm.- The Cell Surface.- Cell Permeability.- Structure of Plasmatic Membrane.- Cell Organisation.- 3: General Characteristics of the Cell-Drug System.- Dimensions of Molecules and Cells.- The Number of Molecules in Single Cells.- The Number of Enzyme Molecules per Cell.- Lethal Doses of Drugs per Cell.- Effective Doses of Drugs per Cell.- Minimum Active Doses of Drugs per Organism.- Minimum Active Dilutions of Drugs.- Intracellular Administration of Drugs.- Types of Action of Drugs on Cells.- Discussion.- 4: Reactions between Drugs and Active Proteins.- Symplex Compounds.- Combination of Haemoglobin with Oxygen and Carbon Monoxide.- Antagonism of Oxygen and Carbon Monoxide.- Discussion.- 5: The Action of Drugs on Catalysts and Enzymes.- Poisoning of Inorganic Catalysts.- General Characters of Enzymes.- Enzyme Activity.- General Characters of the Poisoning of Enzymes.- Diphasic Actions of Enzyme Poisons.- The Rate of Action of Enzyme Poisons.- Relation between Concentration of Poison and Inhibition of Enzyme.- Discussion.- 6: Action of Heavy Metals on Enzymes in vitro and in vivo.- Action of Heavy Metals on Saccharase.- Concentration-action Relations of Heavy Metals and Enzymes.- The Action of Metals on Living Cells.- Relation between Metal Concentration and Action on Cells.- Minimum Lethal Concentrations of Heavy Metals.- Relative Toxicity of Metals.- Course of Reaction between Metals and Cells.- Diphasic Actions of Metals on Cells.- Discussion.- 7: Action of Various Enzyme Poisons in vitro and in vivo.- The Action of Dyes on Enzymes.- Action of Quinine on Enzymes.- Action of Quinine on Cells.- Action of Cyanide on Enzymes and Cells.- Diphasic Actions of Cyanide.- Phenol Compounds.- The Action of Narcotics.- Action of Narcotics on Enzymes.- Action of Narcotics on Cells.- Theories of Narcotic Action.- Discussion.- 8: Concentration-action Relations I.- (1) Classification of Concentration-action Curves.- Relations Depending on Mass-action p..- All-or-None Effects p..- (2) Concentration-action Relations Attributable to Mass-action Laws.- The Mode of Action of Acetylcholine p..- Amount of Aeetylcholine Acting on Cells p..- Individual Variation p..- Site of Action of Acetylcholine p..- Influence of Temperature on Acetylcholine Response p..- Specificity of Aeetyleholine Action p..- Possible Nature of Acetylcholine Receptors p..- Acetylcholine Esterase p..- Concentration-action Relations of Adrenaline p..- Dosage of Adrenaline p..- Concentration-action Relations Found with Various Hormones p..- Insulin p..- Thyroxin p..- Posterior Pituitary Principles p..- Sex Hormones p..- Various Alkaloids p..- Nicotine p..- Physostigmine p..- Other Alkaloids p..- 9: Concentration-action Relations II.- (3) Linear Relations; Action of Narcotics.- (4) All-or-None Responses.- Instrumental Errors p..- Distortion by the Cell of some Chemical Relation p..- Obligatory All-or-None effects p..- All-or-None Cellular Responses p..- Concentration-action Curves with Guinea Pig’s Uterus p..- Drugs Producing All-or-None Effects p..- Discussion p..- 10: Quantitative Pharmacology and the Theory of Humoral Transmission.- Quantitative Data.- Rate of Action.- Concentration-action Relations.-Specific Antagonisms.- Discussion.- 11: Kinetics of Drug Action.- Sources of Error in Kinetic Measurements.- (1) Kinetics of Reactions in Heterogenous Systems.- (2) Kinetics of Cell Reaction.- Delays in Drug Action Due to Diffusion to Cell Surface p..- Penetration of Cells p..- Delay in Biological Response p..- (3) Maximum Rate of Drug Action.- 12: The Rate of Action of Drugs on Cells.- (1) Curves Relating Time and Graded Action.- The Shapes of Time-action Curves p..- (2) Curves Relating Time and All-or-None Effects.- Kinetics of Protein Precipitation p..- Precipitation of Protein by Phenol p..- (3) Time Action Curves as Expressions of Variation.- Calculation of Time-action Curves p..- Time Relations of Toxic Action of Copper on Algae p..- (4) Implications of Monomolecular Theory.- Quantitative Measurements of Drug Uptake p..- Drug Actions as Chain Processes p..- (5) Mortality Curves.- (6) Action of Radiations.- Discussion p..- 13: Time-concentrations Curves.- (1) Form of Curves and Possible Significance.- (2) Time-concentration Curves of Nerve Paralysis.- (3) Time-concentration Curves with Various Drugs.- (4) Time-concentration Relations in Disinfection.- (5) Toxic Vapours.- Deviation of Narcotics p..- Time-concentration Curves of Anaesthetics p..- Time-concentration Curves of Hydrocyanic Acid p..- Irritant Gases p..- Discussion p..- 14: Individual Variation of Response to Drugs.- Methods of Measurement of Individual Variation.- Skew Variation in Biological Material.- Normal Equivalent Deviation.- Errors in Construction of Characteristic Curves.- Uniformity of Population.- Errors of Sampling.- 15: Relation between Various Types of Curves Expressing Response of Cells to Drugs.- (1) Concentration-action Curves as Expressions of Individual Variation.- Virus Infections p..- Discussion p..- (2) Characteristic Curves as Expressions of Chemical Processes.- (3) Correlation between Concentration-action Curves and Characteristic Curves.- Examples of Skewed Characteristic Curves p..- All-or-None Effects p..- Discussion p..- (4) Drug Responses and Individual Variation.- 16: Special Problems Relating to Variation of Populations.- Uniformity of Population.- Influence of Sex, Age and Weight on Response to Drugs.- Seasonal Variations in Sensitivity.- Variation in Human Populations.- Hypersensitivity and Idiosyncrasy.- Margin of Safety with Massive Doses.- Disinfection, etc..- 17: Quantitative Aspects of Drug Antagonism and of Drug Synergism.- The antagonism of cyanides by narcotics.- Selective Antagonisms with Haemoglobin.- Antagonism in Enzyme Poisoning.- Acetyl Choline-Atropine Antagonism.- Adrenaline-Ergotoxine Antagonism.- Synergists of Adrenaline.- Comparison of Antagonisms found with Enzymes and with Hormones.- 18: Qualitative Aspects of Drug Antagonism.- Antagonism of Adrenaline.- Chemical Structure of Acetyl Choline Antagonists.- Acetyl Choline Antagonism in Different Tissues.- Analysis of Drug Actions by Drug Antagonisms.- General Theory of Drug Antagonisms.- 19: Alternative Theories of Drug Action.- Monomolecular Theory.- The Potential Theory of Drug Action.- Phasic response of cells.- Arndt-Schulz Law.- Drug Responses as Expression of Individual Variation.- Weber-Fechner Law.- Discussion.- 20: Quantitative Aspects of Chemotherapy.- Action of Metallic Compounds.- Action of Non-metallic Compounds.- Drug-resistance.- Discussion.- 21: Conclusion.- Index of Authors.- Index of Subjects.
      Hoppa över listan

      Mer från samma serie

      J. Bock, R. Boehm, E. Bürgi, M. Cremer, Arthur R. Cushny, Walter E. Dixon, A. Ellinger, Ph. Ellinger, E. St. Faust, Alfred Fröhlich, H. Fühner, R. Gottlieb, O. Gros, A. Heffter, L. J. Henderson, W. Heubner, R. Höber, Reid Hunt, Martin Jacoby, G. Joachimoglu, A. Jodlbauer, R. Kobert, M. Kochmann, A. Loewy, R. Magnus, J. Pohl, E. Poulsson, E. Rohde, E. Rost, K. Spiro, W. Straub, P. Trendelenburg, W. Wiechowski - Pyridin, Chinolin, Chinin, Chininderivate. Cocaingruppe. Curare und Curarealkaloide. Veratrin und Protoveratrin. Aconitingruppe. Pelletierin. Strychningruppe. Santonin. Pikrotoxin und verwandte Körper. Apomorphin, Apocodein, Ipecacuanha-Alkaloide. Colchic, Häftad

      Pyridin, Chinolin, Chinin, Chininderivate. Cocaingruppe. Curare und Curarealkaloide. Veratrin und Protoveratrin. Aconitingruppe. Pelletierin. Strychningruppe. Santonin. Pikrotoxin und verwandte Körper. Apomorphin, Apocodein, Ipecacuanha-Alkaloide. Colchic

      J. Bock, R. Boehm, E. Bürgi, M. Cremer, Arthur R. Cushny, Walter E. Dixon, A. Ellinger, Ph. Ellinger, E. St. Faust, Alfred Fröhlich, H. Fühner, R. Gottlieb, O. Gros, A. Heffter, L. J. Henderson, W. Heubner, R. Höber, Reid Hunt, Martin Jacoby, G. Joachimoglu, A. Jodlbauer, R. Kobert, M. Kochmann, A. Loewy, R. Magnus, J. Pohl, E. Poulsson, E. Rohde, E. Rost, K. Spiro, W. Straub, P. Trendelenburg, W. Wiechowski

      Häftad, 1920

      514 kr

      M. Kochmann - Narkotica der Fettreihe, Häftad

      Narkotica der Fettreihe

      M. Kochmann

      Häftad, 1936

      565 kr

      A. Heffter - Allgemeines zur Pharmakologie der Metalle — Eisen — Mangan — Kobalt — Nickel, Häftad

      Allgemeines zur Pharmakologie der Metalle — Eisen — Mangan — Kobalt — Nickel

      A. Heffter

      Häftad, 1934

      529 kr

      Karl J. Anselmino, NA Hoffmann - Die Wirkstoffe des Hypophysenvorderlappens, Häftad

      Die Wirkstoffe des Hypophysenvorderlappens

      Karl J. Anselmino, NA Hoffmann

      Häftad, 1941

      581 kr

      Ernst W. Alther - Pharmacology of Fluorides, Häftad

      Pharmacology of Fluorides

      Ernst W. Alther

      Häftad, 1966

      1 124 kr

      Zénon-Marcel Bacq, Johannes Carl Bock, Gustav V. R. Born, Oskar Eichler, Alfred Farah, Arthur Heffter, Wolfgang Heubner, Josef Schüller - Infektionen I, Häftad

      Infektionen I

      Zénon-Marcel Bacq, Johannes Carl Bock, Gustav V. R. Born, Oskar Eichler, Alfred Farah, Arthur Heffter, Wolfgang Heubner, Josef Schüller

      Häftad, 1964

      581 kr

      Gustav Jantsch, Svend Kühnel Hagen - Elemente der Vierten Hauptgruppe II, Häftad

      Elemente der Vierten Hauptgruppe II

      Gustav Jantsch, Svend Kühnel Hagen

      Häftad, 1956

      565 kr

      Hans Grassmann - Elemente der Vierten Hauptgruppe I, Häftad

      Elemente der Vierten Hauptgruppe I

      Hans Grassmann

      Häftad, 1963

      565 kr

      Otto Schmitz-DuMont, Mark von Stackelberg, Oldřích Tomíček - Elemente der Sechsten Gruppe, Häftad

      Elemente der Sechsten Gruppe

      Otto Schmitz-DuMont, Mark von Stackelberg, Oldřích Tomíček

      Häftad, 1948

      565 kr

      Oskar Eichler, Helmut Haase - Erzeugung von Krankheitszuständen durch das Experiment, Häftad

      Erzeugung von Krankheitszuständen durch das Experiment

      Oskar Eichler, Helmut Haase

      Häftad, 1965

      581 kr

      Hoppa över listan

      Du kanske också är intresserad av

      Alfred J. Clark - General Pharmacology, E-bok

      General Pharmacology

      Alfred J. Clark

      E-bok
      2012

      732 kr

      Alfred J. Clark - General Pharmacology, Häftad
      Del 4

      General Pharmacology

      Alfred J. Clark

      Häftad, 2012

      566 kr

      Rudolf Rigler, K. Roholm - Handbuch der Experimentellen Pharmakologie, Häftad

      Handbuch der Experimentellen Pharmakologie

      Rudolf Rigler, K. Roholm

      Häftad, 1938

      842 kr

      Oskar Eichler, Johannes Carl Bock, Gustav V. R. Born, Alfred Farah, Arthur Heffter, Wolfgang Heubner, Josef Schüller - Die Pharmakologie Anorganischer Anionen, Övrigt

      Die Pharmakologie Anorganischer Anionen

      Oskar Eichler, Johannes Carl Bock, Gustav V. R. Born, Alfred Farah, Arthur Heffter, Wolfgang Heubner, Josef Schüller

      686 kr

      Oskar Eichler, Helmut Haase - Erzeugung von Krankheitszuständen durch das Experiment, Häftad

      Erzeugung von Krankheitszuständen durch das Experiment

      Oskar Eichler, Helmut Haase

      Häftad, 1965

      581 kr

      Hans Grassmann - Elemente der Vierten Hauptgruppe I, Häftad

      Elemente der Vierten Hauptgruppe I

      Hans Grassmann

      Häftad, 1963

      565 kr

      Otto Gessner, George Barger - Ergänzungswerk, Häftad

      Ergänzungswerk

      Otto Gessner, George Barger

      Häftad, 1938

      581 kr

      Brenno Babudieri - Erzeugung von Krankheitszuständen durch das Experiment, Häftad

      Erzeugung von Krankheitszuständen durch das Experiment

      Brenno Babudieri

      Häftad, 1973

      581 kr

      A. Heffter - General Pharmacology, Häftad

      General Pharmacology

      A. Heffter

      Häftad, 1937

      581 kr

      Johannes Carl Bock, Gustav V. R. Born, Oskar Eichler, Ervin George Erdös, Alfred Farah, Arthur Heffter, Wolfgang Heubner, Josef Schüller - General Pharmacology, Häftad

      General Pharmacology

      Johannes Carl Bock, Gustav V. R. Born, Oskar Eichler, Ervin George Erdös, Alfred Farah, Arthur Heffter, Wolfgang Heubner, Josef Schüller

      Häftad, 1970

      581 kr