Primary Immunodeficiency Diseases

Nima Rezaei gained his medical degree from Tehran University of Medical Sciences in 2002 and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Since 2010, Dr. Rezaei has worked at the Department of Immunology and Biology, School of Medicine, Tehran University of Medical Sciences; he is now the Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences, the Director of Global Academic Program, Tehran University of Medical Sciences, and the co-founder and Deputy President of the Research Center for Immunodeficiencies. In addition, Dr. Rezaei is an Honorary Associate Staff at the Department of Infection and Immunity, School of Medicine and Biomedical Sciences, University of Sheffield. He is also the founderand president of Universal Scientific Education and Research Network (USERN). Dr. Rezaei has already been the Director of more than 50 research projects and has designed and participated in several international collaborative projects. Dr. Rezaei is an editorial assistant or board member for more than 20 international journals. He has edited more than 10 books, has presented more than 350 lectures/posters in congresses/meetings, and has published more than 500 articles in the international scientific journals during last decade.

“The purpose is to provide an up-to-date, comprehensive resource for physicians and nurses who have an interest in learning more about immunodeficiencies. … This book’s approach is well organized, up to date, and easy to follow. … I highly recommend this book as a current and comprehensive resource, which also has great clinical relevance for medical students, residents and fellows, and general providers, as well as subspecialists including immunologists.” (Joseph R. Hageman, Doody's Book Reviews, July, 2017)“This updated text reviews in detail in 10 chapters the recent advances in this field. Clearly written, the authors review the clinical history, genetic diagnosis of the different entities and their management. For all pediatricians, geneticists and immunologists.” (Zvi Laron, Pediatric Endocrinology Reviews (PER), Vol. 14 (4), June, 2017)

• Introduction on Primary Immunodeficiency Diseases.- Combined T- and B-Cell Immunodeficiencies.- Predominantly Antibody Deficiencies.- Phagocytes Defects.- Genetic Disorders of Immune Regulation.- Defects in Intrinsic and Innate Immunity: Receptors and Signaling Components.- Autoinflammatory Disorders.- Complement Deficiencies.- Other Well-Defined Immunodeficiencies.- Syndromic Immunodeficiencies.