Metalloproteinases as Targets for Anti-Inflammatory Drugs

Inbunden, Engelska, 1999

Del i serien Progress in Inflammation Research

2 242 kr

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Beskrivning

This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. This volume is intended not only for those active in research into metalloproteinases but also for those with an interest in inflammatory diseases. Thus it addresses both academic and industrial researchers.

Produktinformation

Utgivningsdatum:1999-12-01
Mått:155 x 235 x 19 mm
Vikt:547 g
Format:Inbunden
Språk:Engelska
Serie:Progress in Inflammation Research
Antal sidor:207
Upplaga:1999
Förlag:Birkhauser Verlag AG
ISBN:9783764358563

Utforska kategorier

Farmakologi inom Medicin

Innehållsförteckning

Structural characteristics of the matrix metalloproteinases.- Matrix metalloproteinase inhibitors.- Role of stromelysin-1 in cartilage metabolism.- Matrix metalloproteinases in neuro-inflammatory disease.- Membrane type matrix metalloproteinases: Regulators of focal proteolysis.- Aggrecanase and cartilage proteoglycan degradation.- Overview of the biological roles of metalloproteinases in health and disease.- Adhesion molecule sheddases.- TNF? converting enzyme.