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Beskrivning
Focusing on the interaction between heart and the vascular system, this text provides a synthesis of information on cardiac dysfunction, vascular modification of cardiac function, and cardiac-vascular remodelling. Among the topics covered are: vascular-ventricular interference and remodelling; right-left ventricular interaction; systolic-diastolic interaction; ventricular-endocardial interaction; and coronary circulation-ventricular interaction.
1 Ventricular-Vascular Adaptation and Remodeling Vascular Remodeling.- During Heart Failure.- Myocardial Interstitial Collagen Matrix Remodeling in Response to a Chronic Elevation in Ventricular Preload or Afterload.- Myocardial Hypertrophy and Coronary Circulation Before and After Relief of Pressure Overload.- Cardiac Hypertrophy and the Renin-Angiotensin System.- The Role of Manganese Superoxide Dismutase in the Acquisition of Tolerance of the Heart to Ischemia: Molecular Adaptation to Ischemia.- Remodeling: How Vessels Narrow.- 2 Systolic-Diastolic Interaction.- Interaction Between Left-Ventricular Function and Loading Condition in Cardiovascular Disease.- Intraventricular Interaction.- Adaptation of the Cardiac Cell to Loading: Function in Heart Failure.- Transient Hemodynamic Perturbations: An Approach to the Study of Ventricular Interaction and Restoring Forces.- Extrinsic Versus Intrinsic Determinants of the Diastolic Pressure-Volume Relation.- Endocardial-Myocardial Interaction.- 3 Ventricular—Vascular Interaction.- Arterial Compliance as Load on the Heart.- Optimal Afterload that Maximizes External Work and Optimal Heart that Minimizes O2 Consumption.- Influence of Aortic Impedance on the Development of Pressure-Overloaded Left-Ventricular Hypertrophy in Rats.- The Arterial Response to an Exercise Stress Test in Healthy Subjects, Hypertensives, and Patients with Left-Ventricular Dysfunction.- Altered Left-Ventriculoarterial Coupling in Mitral Regurgitation.- Aging Changes in the Systemic Circulation and Ventriculovascular Coupling.- The Veins and Ventricular Preload.- Role of Endothelium in Control of Regional Blood Flow in Humans.- Dynamic Characteristics of the Pulmonary Circulation.- Intramyocardial Regulation of Coronary Dynamics.- Coronary SloshPhenomenon and Behavior of Intramyocardial Microcirculation.- Coronary-Ventricular Interaction: The Gregg Phenomenon.- Influences of Coronary Venous Pressures on Left-Ventricular Function.- Coronary Pressure-Flow Relations.- Nitric Oxide and the Heart: Implications in Physiological and Pathological Conditions.- Cardiac Mechanoenergetics and Coronary Circulation.