Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis

AvO.R. Hommes,G. Comi

Häftad, Engelska, 2012

Del i serien Topics in Neuroscience

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Beskrivning

There is now evidence that irreversible brain damage accumulates very early in the course of multiple sclerosis. These findings provide the rationale for early treatment and emphasize the importance of clinical trials in early multiple sclerosis.

Produktinformation

Utgivningsdatum:2012-09-28
Mått:155 x 235 x 13 mm
Vikt:341 g
Format:Häftad
Språk:Engelska
Serie:Topics in Neuroscience
Antal sidor:199
Förlag:Springer Verlag
ISBN:9788847021716

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Innehållsförteckning

1 – Evidence for an Early Treatment of Multiple Sclerosis.- 2 – Inflammation, Demyelination, and Axonal Degeneraton: Three Aspects of the Pathogenesis of Multiple Sclerosis Revealed by Campath-1 H Treatment.- 3 – Genetic Regulation of Nerve Cell Death/Glial Activation and Protective Effects of Myelin Basic Protein Autoimmune Neurotrophin Production in Mechanically Induced Neurodegeneration.- 4 – Neuroprotective Treatment in Primary Progressive Multiple Sclerosis: A Phase I/II Study with Riluzole.- 5 – Neuropathology and Disease Progression in Multiple Sclerosis.- 6 – Autoimmune Inflammation and Multiple Sclerosis.- 7 – Early Treatment of Progression in Multiple Sclerosis.- 8 – Imaging for Tissue Characterization in Multiple Sclerosis and Other White Matter Diseases.- 9 – Monounsaturated Fatty Acids and Neuroprotection. The Results of a Study of Cognitive Decline in Old Age. Is There a Case for this Treatment in Multiple Sclerosis?.- 10 – Neuroprotection in Acute Ischemic Stroke: Lessons for Early Treatment in Multiple Sclerosis.- 11 – Soluble VCAM-1 Release Indicates Inflammatory Blood-Brain Barrier Pathology and Further Modulates Adhesion.- 12 – Early Treatment in Multiple Sclerosis with Intravenous Immunoglobulin: Rationale and Study Design.- 13 – Serial Magnetic Resonance Imaging in Patients with a First Clinical Episode Suggestive of Multiple Sclerosis: Outline of a Research Protocol.- 14 – T1-Hypointense Lesions (T1 Black Holes) in Mild-to-Moderate Disability Relapsing Multiple Sclerosis.- 15 – Acute Monosymptomatic Optic Neuritis: Potential Clues to Early Therapy in Multiple Sclerosis.- 16 – Antibody Mediated Demyelination.- 17 – Anti-MOG Antibodies as Early Predictors for Conversion to Relapsing-Remitting Disease Course inPatients Suggestive of Multiple Sclerosis.- 18 – Sunlight, Vitamin D, and Multiple Sclerosis.- 19 – The Yin and Yang of Inflammation in Multiple Sclerosis.- 20 – Management of Interferon-ß1b (Betaseron) Failures in Multiple Sclerosis with Interferon-?n3 (Alferon N).