Biological Kinetics

AvElena Burlakova,Sergey Dmitrievich Varfolomeev

Inbunden, Engelska, 2005

7 248 kr

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Beskrivning

This volume discusses questions of free-radical biology and new, modern directions in molecular cytobiology; proteomics and genomics. The book presents articles and reviews on bioantioxidants, synthesis of new compounds, mechanisms of their action and areas of application. Studies on free radical states using ESR technique, biochemistry of regulatory systems and the role of free radicals in radiation disease and cancer development are given special attention. Test results of new drugs for curing malignant tumors and kinetic approaches to the description of disease development and estimation of curative action of medicinal preparations are shown. The book also presents studies in the branch of enzymology, receptor systems, photoreception, in particular. The volume uniquely presents general tendencies in chemistry, biology and medicine kinetically united and attached to free radical mechanisms and other questions under consideration.

Produktinformation

Utgivningsdatum:2005-10-28
Mått:156 x 234 x undefined mm
Vikt:453 g
Format:Inbunden
Språk:Engelska
Antal sidor:562
Förlag:Brill
ISBN:9789067644310

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Fysikalisk kemi inom Naturvetenskap och teknik

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Elena Burlakova, Sergey Dmitrievich Varfolomeev

Innehållsförteckning

Introduction; Bioantioxidants: yesterday, today, tomorrow; Peroxide oxidation of lipids in biological membranes and food additives; The influence of antioxidants on the signaling system of sphingomyelinic cycle and apoptosis; The features of biological membrane lipid peroxide oxidation under the effect of ultra-low concentrations of antioxidants; Structure, pharmacological properties and medical application of heteroaromatic antioxidants; The mechanisms of photodamaging of visual retinal and pigment epithelium cells of the eye Ill and The antioxidant role of shielding eye pigments - melanins and ommochromes, and physicochemical mechanism of their action; Enzymatic catalysis: kinetics, active site structure, Bioinformatics; Enzymes and their regulators in modern drugs; Structure and functions of firefly luciferase; Stabilization of subcellular structures by functioning: a creative approach to solution of many problems Volume II. Biological Kinetics; Protein aggregation kinetics; Nikolai M. Emanuel - the originator of biochemical investigations in the field of chemotherapy in Institute of Chemical Physics, RAS; Antitumor effects of nitric oxides and NO-donors; Nitrosoalkylureas in modern antitumor chemotherapy and The value of antioxidant properties of lipids in radiation damage and membrane repair; Molecular and cellular mechanisms of the et al organism responses to damages and their modification by compounds and Radioprotection of DNA with free radical reaction inhibitors - a welfare or ...? Steric modeling and establishing of the embryo, cells are synthesizing transitory perichromosomal DNA-containing organelles necessary for interpreting positional information; Mitochondria: oxidative stress, mitochondrial DNA mutation, pathologies, aging and apoptosis; The study of biological activity of antioxidants on Morozova, and herbal objects; Chemical and Biological Kinetics. New Horizons; Principles of genetic activity of nitric oxide (NO) and NO-donating agents in modeling of the cell stress response and new drug development