Hyperthermic Oncology from Bench to Bedside

Häftad, Engelska, 2018

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Beskrivning

It also presents state-of-the-art clinical outcomes by hyperthermia treatment of cancer. In the past few decades, basic and clinical research have shown through in vitro experiments that hyperthermia inhibits epithelial-mesenchymal transition (EMT), resulting in the prevention of metastasis.

Produktinformation

Utgivningsdatum:2018-06-07
Mått:155 x 235 x 23 mm
Vikt:769 g
Format:Häftad
Språk:Engelska
Antal sidor:444
Förlag:Springer Verlag, Singapore
ISBN:9789811092350

Utforska kategorier

Onkologi inom Medicin
Medicinsk bildbehandling inom Medicin

Mer om författaren

Dr. Satoshi KokuraKOKURA Lab, Health and MedicalSciences, Kyoto Gakuen UniversityKyoto, JapanDr. Toshikazu YoshikawaPresidentKyoto Prefectural University ofMedicineKyoto, Japan Dr. Takeo OhnishiDepartment of Radiation OncologyNara Medical UniversityNara, Japan

Innehållsförteckning

Part I. Basic Science in Cultured Cells.- 1. Introduction.- 2.Induction of oxidative stress by hyperthermia and enhancement of hyperthermia-induced apoptosis by oxidative stress modification.- 3.Molecular Damage: Hyperthermia Alone.- 4.Roles of HSF1 and Heat Shock Proteins in Cancer.- 5.Cellular Responses in Signal Transduction Pathways Induced by Hyperthermia.- 6.Cell cycle responses to hyperthermia.- 7.Thermo-tolerance.- 8.Enhancement of Hyperthermia on Radio-sensitivity.- 9.Inhibition of DNA repair system activity.- 10. Enhancement of Hyperthermia on Anti-tumor Drug Sensitivity.- 11. Inhibition of epithelial-to-mesenchymal transition (EMT) by hyperthermia.- Part II. Basic Science in Whole Body.- 12.Potentiating Immune System by Hyperthermia.- 13. Magnetic Nanoparticle-Mediated Hyperthermia and Induction of Anti-Tumor Immune Responses.- 14. Tumor Microenvironment and Hyperthermia Part III. Clinical Science inCancer Patients..- 15. Hyperthermia Alone.- 16.Combination by Hyperthermia and Radiation (and Chemotherapy): Oral and Maxillofacial Cancer.- 17.Combination by Hyperthermia and Radiation (and Chemotherapy): Lung Cancer.- 18.Efficacy of hyperthermia in combination with radiation therapy for breast cancer.- 19.Combination by Hyperthermia and Radiation: Esophageal Cancer.- 20.Combination by Hyperthermia and Radiation (and Chemotherapy): Gynecology Cancer.- 21.Combination by Hyperthermia and Radiation and Chemotherapy: Soft Tissue Sarcoma.- 22.Combination by Hyperthermia and Chemotherapy: Lung Cancer.- 23. Combination by Hyperthermia and Chemotherapy: Breast Cancer.- 24.Combination by Hyperthermia and Chemotherapy: Esophageal Cancer.- 25.Combination by Hyperthermia and Chemotherapy: Liver Cancer.- 26.Hyperthermia Combined with Chemotherapy: Pancreatic Cancer.- 27.Effect of hyperthermia in combination with chemotherapy and radiation therapy for treatment of urological cancer (prostate cancer and urothelial cancer).- 28.Combination by Hyperthermia and Surgery.- 29.Combining Hyperthermia and Immunotherapy: NK Therapy and Hyperthermia.- 30.Combination by Hyperthermia and Immunotherapy: DC Therapy and Hyperthermia.- 31.Effects of fever-range hyperthermia on T cell-mediated immunity: possible combination of hyperthermia and T cell-based cancer immunotherapy.- 32.Combination of Hyperthermia and Immunotherapy: Hyperthermia and Naive T-cell Therapy.- 33.HIPEC for Peritoneal Dissemination.- 34.A new comprehensive treatment for peritoneal metastases using cytoreductive surgery combined with hyperthermic intraperitoneal chemoperfusion.- 35.Non-invasive Temperature Moniterring.- 36.Development of Heating Device.- 37. Epilogue.