Tarik F. Massoud – författare

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field.

Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood.

Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field.Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood.- Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance- Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance- Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

In this issue of Neuroimaging Clinics, guest editor Dr. Tarik F. Massoud brings his considerable expertise to the topic of Neuroimaging Anatomy, Part 1: Brain and Skull. Anatomical knowledge is critical to reducing both overdiagnosis and misdiagnosis in neuroimaging. This issue is part one of a two-part series on neuroimaging anatomy that focuses on the brain, with each article addressing a specific area. The issue also includes an article on Brain Connectomics: the study of the brain's structural and functional connections between cells.

In this issue of Neuroimaging Clinics, guest editor Dr. Tarik F. Massoud brings his considerable expertise to the topic of Neuroimaging Anatomy, Part 2: Head, Neck, and Spine. Anatomical knowledge is critical to reducing both overdiagnosis and misdiagnosis in neuroimaging. This issue is part two of a two-part series on neuroimaging anatomy that focuses on the head, neck, and spine. Each article addresses a specific area such as the orbits, sinonasal cavity, temporal bone, pharynx, larynx, and spinal cord.

In this issue of Neuroimaging Clinics, guest editors Drs. Bryan Lanzman and Tarik F. Massoud bring their considerable expertise to the topic of The Subarachnoid Space: Percutaneous Access for Diagnosis and Image-Guided Therapies. In this first-of-its-kind issue, top experts the field discuss a wide range of topics related to the subarachnoid space, including imaging anatomy, guided lumbar punctures, puncture complications, myelography, cisternography, and much more.

In this issue of Neuroimaging Clinics, guest editors Drs. Tarik F. Massoud and Syed Hashmi bring their considerable expertise to the topic of Clinical Imaging of the Spinal Cord: An Update. Top experts discuss structural MRI of the spinal cord; myelographic imaging of disorders affecting the spinal cord; imaging of spinal cord infections; imaging of spinal cord inflammatory disorders; and more.

Perhaps no artery in the human body bears as much importance to bodily functions and life as the basilar artery, by virtue of the anatomical territories it serves. This is due to the critical nature of the physiological functions supported by the brainstem, the nearby cerebellum and cerebrum, and the severity of most pathological conditions known to affect this artery, and the risk involved in treating those conditions. This book is a comprehensive resource of knowledge on the anatomical, radiological, developmental, clinical, and technical aspects relevant to the diagnosis and treatment of basilar artery diseases. Until now, no single book has been available as a wide-ranging resource of clinically relevant information on the basilar artery, its pathology, and various treatment options. The co-editors are experienced academic clinicians with active interests in clinical neurovascular imaging and cerebrovascular surgery, who have worked within vibrant hospital and academic settings at the forefront of the best clinical practices related to diseases involving the basilar artery. The co-editors’ clinical experience has been acquired in centers of excellence across the USA, Europe, and the Far East. In compiling this book, the co-editors have also called upon many of the world’s best basic and clinical neuroscientists, specializing in knowledge of clinical conditions affecting the basilar artery, for their expert input on the latest clinical management of patients with diseases involving this artery. This book is intended for neuroradiologists, neurosurgeons, neurologists, neurointensivists, and other physicians and scientists engaged in the study and clinical management of patients with disease of the basilar artery and its vascular territories of the brain. It should also serve as a unique educational and research resource for students and more experienced practitioners alike within this important area of clinical medicine.

Disease of the blood vessels of the brain currently ranks among the leading causes of death in western countries and leads to significan problems in health care. The neurological effects of non-fatal strokes can be devastating. Modern treatment methods, however, can significantly alleviate these. The improvements have been developed from an understanding of the biophysical basis of blod flow in the brain. This textbook provides a review of our current understanding of the physical phenomena associated with the flow of blood through the brain and applies these concepts to the physiological and medical aspects of cerebrovascular disease in a way that will be useful to both the scientist and the clinician. Specifically it discusses: - the physical bases for the development of cerebrovascular disease and for its clinical consequences - specific current and possible future therapies - experimental, clinical, and computational techniques used to investigate cerebrovascualr disease - blood dynamics and its role - imaging methods used in the diagnosis and management of cerebrovascualr disease. Intended for a one- or two-semester course in biophysics, biomedical engineering or medical physics, the book will also be of interest to medical students and interns in neurology and cardiology and will provide a useful overview of current practice for researchers and clinicians. A volume in the AIP International Series in Basic and Applied

This book is an introduction to neuroradiology, specifically designed for the needs of first-year residents. Currently available textbooks, while excellent reference books, provide far too much material than is needed for radiology residents, particularly those on first-year rotations. This book covers information important both from a practical standpoint and for later board preparation in a short and simple format.The book is divided into three main sections: Brain, Spine, and Head and Neck. Using an easy-to-read bulleted format, this book covers all the necessary material for a first year resident and high-yield, often-tested topics, making it additionally a useful study guide for board preparation later in residency. In addition, it provides valuable tips on how to approach and interpret CT and MRIs of the brain, spine and head and neck. Additional included coverage makes it useful in later rotations of more specialized areas like the eyes and temporal bone structures.Key topics include neuroimaging structural and functional anatomy, neurodegenerative disorders, and facial and skull base fracture imaging. Like other books in this series, a critical component of What Radiology Residents Need to Know: Neuroradiology will be the additional images found online only. These images amount to twice the number in the print and e-book versions to fully illustrate points made in the text.This is an ideal guide for first year radiology residency learning neuroradiology.