In this fourth edition of Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases, the text has been thoroughly amended, updated, and partially rearranged to reflect the latest advances. In addition to discussing the role of pinhole imaging in the range of disorders previously covered, the new edition pays detailed attention to the novel diagnostic use of gamma correction pinhole bone scan in a broad spectrum of skeletal disorders. A large number of state of the art pinhole scans and corroborative CT, MRI, and/or ultrasound images are presented side by side. The book has been enlarged to encompass various new topics, including occult fractures; cervical sprain and whiplash trauma; bone marrow edema; microfractures of trabeculae; evident, gaping, and stress fractures; soft tissue diseases; and differential diagnosis. This new edition will be essential reading for practitioners and researchers in nuclear medicine, radiology, orthopedic surgery, and pathology.

Nuclear Medicine techniques have advanced to such a degree that biochemical transparency of the human body has reached the doorstep of medical application. The book gives background, techniques and examples in an interdisciplinary approach to quantify biochemical reactions in vivo by regional imaging and in vitro analyses. The goal is to assess in vivo biochemical homeostatic circuits under control by genes and protein interactions. It becomes apparent how nuclear medicine can aid clinical researchers and practitioners, human geneticists and pharmacologists in understanding (and affecting) gene-phenotype relationships operating in vivo and thus can help eventually to bring functional genomics and proteomics to clinical medicine.

In the fifth edition of this highly successful book, the author once again aims to equip the reader with up-to-date information that will facilitate accurate diagnosis of bone and joint diseases by means of combined use of scintigraphy and radiology. Two entirely new chapters have been added, one on the use of 18F-NaF PET/CT and the other on gamma correction scan diagnosis of bone trabecular microfracture and microcontusion as well as bone edema and hemorrhage. Further topics covered for the first time include enthesopathies, myositis, soft tissue diseases, cryptic bones, and differential diagnosis. Individual chapters have been updated and rearranged to reflect the latest advances in imaging diagnosis. As before, a vast number of state of the art gamma correction pinhole bone scans and corroborative conventional radiographs and CT, MRI, and/or ultrasound images are presented side by side. In this new edition, extension of the application of gamma correction to other imaging methodssuch as MRI and CT and the solution of the halation problem are necessarily addressed. This fifth edition of Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases will be essential reading for practitioners and researchers in nuclear medicine, radiology, orthopedic surgery, pathology, anatomy, and imaging sciences at large.

This excellently illustrated monograph summarizes the updated fresh information on the theoretical, practical, and rapidly extended facets of gamma correction 99mTc-hydroxymethylene diphosphonate pinhole bone scan (99mTc-GCPBS) to MRI, CR, and MDCT.  Basically, 99mTc-GCPBS is able to precisely visualize and quantitate callused trabecular microfracture (CTMF) which is as little as 200 μm in size. The extended gamma correction images can very neatly demonstrate CTMF on MRI, conventional radiography (CR), and multidetector computed tomography (MDCT). Whenever appropriate, histological correlation is provided in conjunction with fine gamma corrected images. In this setting, ACDSee 10 gamma correction MRI and CR have been found to offer a highly useful option that deserves wider clinical interest. In practice, gamma correction MRI, CR, and MDCT can distinctly visualize CTMF so that CTMF can be precisely measured simply using an optic lens. By comparison, the naïve MRI, for example,shows CTMF which measures as big as 2 mm in size.  Furthermore, 99mTc-GCPBS can now differentiate bone marrow edema from hemorrhage using the visuospatial mathematic method, which includes the ImageJ of the NIH.

In this fourth edition of Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases, the text has been thoroughly amended, updated, and partially rearranged to reflect the latest advances. In addition to discussing the role of pinhole imaging in the range of disorders previously covered, the new edition pays detailed attention to the novel diagnostic use of gamma correction pinhole bone scan in a broad spectrum of skeletal disorders. A large number of state of the art pinhole scans and corroborative CT, MRI, and/or ultrasound images are presented side by side. The book has been enlarged to encompass various new topics, including occult fractures; cervical sprain and whiplash trauma; bone marrow edema; microfractures of trabeculae; evident, gaping, and stress fractures; soft tissue diseases; and differential diagnosis. This new edition will be essential reading for practitioners and researchers in nuclear medicine, radiology, orthopedic surgery, and pathology.

Nuclear Medicine techniques have advanced to such a degree that biochemical transparency of the human body has reached the doorstep of medical application. The book gives background, techniques and examples in an interdisciplinary approach to quantify biochemical reactions in vivo by regional imaging and in vitro analyses. The goal is to assess in vivo biochemical homeostatic circuits under control by genes and protein interactions. It becomes apparent how nuclear medicine can aid clinical researchers and practitioners, human geneticists and pharmacologists in understanding (and affecting) gene-phenotype relationships operating in vivo and thus can help eventually to bring functional genomics and proteomics to clinical medicine.

In the fifth edition of this highly successful book, the author once again aims to equip the reader with up-to-date information that will facilitate accurate diagnosis of bone and joint diseases by means of combined use of scintigraphy and radiology. Two entirely new chapters have been added, one on the use of 18F-NaF PET/CT and the other on gamma correction scan diagnosis of bone trabecular microfracture and microcontusion as well as bone edema and hemorrhage. Further topics covered for the first time include enthesopathies, myositis, soft tissue diseases, cryptic bones, and differential diagnosis. Individual chapters have been updated and rearranged to reflect the latest advances in imaging diagnosis. As before, a vast number of state of the art gamma correction pinhole bone scans and corroborative conventional radiographs and CT, MRI, and/or ultrasound images are presented side by side. In this new edition, extension of the application of gamma correction to other imaging methodssuch as MRI and CT and the solution of the halation problem are necessarily addressed. This fifth edition of Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases will be essential reading for practitioners and researchers in nuclear medicine, radiology, orthopedic surgery, pathology, anatomy, and imaging sciences at large.

This excellently illustrated monograph summarizes the updated fresh information on the theoretical, practical, and rapidly extended facets of gamma correction 99mTc-hydroxymethylene diphosphonate pinhole bone scan (99mTc-GCPBS) to MRI, CR, and MDCT.  Basically, 99mTc-GCPBS is able to precisely visualize and quantitate callused trabecular microfracture (CTMF) which is as little as 200 μm in size. The extended gamma correction images can very neatly demonstrate CTMF on MRI, conventional radiography (CR), and multidetector computed tomography (MDCT). Whenever appropriate, histological correlation is provided in conjunction with fine gamma corrected images. In this setting, ACDSee 10 gamma correction MRI and CR have been found to offer a highly useful option that deserves wider clinical interest. In practice, gamma correction MRI, CR, and MDCT can distinctly visualize CTMF so that CTMF can be precisely measured simply using an optic lens. By comparison, the naïve MRI, for example,shows CTMF which measures as big as 2 mm in size.  Furthermore, 99mTc-GCPBS can now differentiate bone marrow edema from hemorrhage using the visuospatial mathematic method, which includes the ImageJ of the NIH.