Nuklearmedicin

His legacy is emphasized by Waldenström lectures, Waldenström Prizes, and by the International Waldenström’s Macroglobulinemia Foundation, IWMF, and the Bing Center for Waldenström’s macroglobulinemia at the Dana Farber Institute of Cancer Institute of the Harvard University in Boston.

Widely regarded as the cornerstone text in the field, the successful series of editions continues to follow the tradition of a clear and comprehensive presentation of the physical principles and operational aspects of medical imaging.  The Essential Physics of Medical Imaging, 4th Edition, is a coherent and thorough compendium of the fundamental principles of the physics, radiation protection, and radiation biology that underlie the practice and profession of medical imaging. Distinguished scientists and educators from the University of California, Davis, provide up-to-date, readable information on the production, characteristics, and interactions of non-ionizing and ionizing radiation, magnetic fields and ultrasound used in medical imaging and the imaging modalities in which they are used, including radiography, mammography, fluoroscopy, computed tomography, magnetic resonance, ultrasound, and nuclear medicine. This vibrant, full-color text is enhanced by more than 1,000 images, charts, and graphs, including hundreds of new illustrations. This text is a must-have resource for medical imaging professionals, radiology residents who are preparing for Core Exams, and teachers and students in medical physics and biomedical engineering.   Features a new introductory overview, plus new information on informatics-oriented concepts, multisource and other x-ray tubes, new quality control procedures for digital radiography, digital breast tomosynthesis, dedicated breast CT, best practices in minimizing fluoroscopy dose to patients and staff, dosimetry in x-ray imaging, 3T and 7T MRI, MR artifacts and solutions, ultrasound elastography, nuclear cardiology,  total-body PET imaging, and much more.Provides clear but detailed explanations of the basic science important to nuclear imaging, including the physical properties and production of radioactivity, radiation detection and measurement and completely updated chapters on radiopharmaceuticals and internal dosimetry, SPECT and PET/CT.Addresses topics common to all forms of diagnostic imaging, including image quality and medical informatics as well as the non-ionizing medical imaging modalities of MRI and ultrasound.Introduces a completely updated radiation biology section with current concepts in biological effects at the molecular, cellular and organ systems levels as well as the acute radiation syndrome and the latest assessment of potential biological effects to the fetus, children and adults from medical imaging procedures, as well as principles for effective risk communication.Updates the radiation protection section relevant to all aspects of medical imaging to the latest concepts in patient and staff protection, including current Joint Commission and regulatory quality assurance requirements, as well as radiological emergency medical management.

This open access textbook focuses on the various aspects of radiobiology. The goal of radiobiological research is to better understand the effects of radiation exposure at the cellular and molecular levels in order to determine the impact on health. This book offers a unique perspective, by covering not only radiation biology but also radiation physics, radiation oncology, radiotherapy, radiochemistry, radiopharmacy, nuclear medicine, space radiation biology & physics, environmental and human radiation protection, nuclear emergency planning, molecular biology and bioinformatics, as well as the ethical, legal and social considerations related to radiobiology. This range of disciplines contributes to making radiobiology a broad and rather complex topic. This textbook is intended to provide a solid foundation to those interested in the basics and practice of radiobiological science. It is a learning resource, meeting the needs of students, scientists and medical staff with an interest in this rapidly evolving discipline, as well as a teaching tool, with accompanying teaching material to help educators.

Dava Sobel, acclaimed and bestselling author of Longitude, chronicles the life and work of the most famous woman in the history of science – and the untold story of the young women who trained in her laboratory. ‘A fresh and feminist study of the pioneering Nobel laureate reveals her impact on the women she mentored and set on the path to prominence’ Observer ‘It is a novel lens through which to view Curie’s story, and Sobel paints her tale with characteristic deftness and eloquence’ Financial Times For decades Marie Curie was the only woman in the room at international scientific gatherings, and despite constant illness she travelled far and wide to share the secrets of radioactivity, a term she coined. She is still the only person to win a Nobel Prize in two scientific fields.Her ingenuity extended far beyond the laboratory walls; grieving the death of her husband, Pierre, she took his place as professor of physics at the Sorbonne, devotedly raised two daughters, drove a van she outfitted with X-ray equipment to the front lines of World War I, befriended Albert Einstein and inspired generations of young women to pursue science as a way of life.Approaching Marie Curie from a unique angle, Sobel navigates her remarkable discoveries and fame alongside the women who became her legacy – from Norway’s Ellen Gleditsch and France’s Marguerite Perry, who discovered the element francium, to her own daughter, Irene, a Nobel Prize winner in her own right. The Elements of Marie Curie deftly illuminates the trailblazing life and enduring influence of one of the most consequential figures of our time. ‘A lucid, literate biography, celebrating a scientific exemplar who, for all her fame, deserves to be better known’ Kirkus ‘As expected from a Pulitzer Prize finalist, Sobel writes beautifully and with clarity about the science that Curie specialised in, making clear the achievements that her lab brought about’ Daily Mail ‘This is an essential read, capturing both [Curie's] genius and her legacy’ New Scientist ‘Sobel’s book is a luminous and illuminating contribution to the cause’ Literary Review

Dava Sobel, acclaimed and bestselling author of Longitude, chronicles the life and work of the most famous woman in the history of science – and the untold story of the young women who trained in her laboratory. ‘A fresh and feminist study of the pioneering Nobel laureate reveals her impact on the women she mentored and set on the path to prominence’ Observer ‘It is a novel lens through which to view Curie’s story, and Sobel paints her tale with characteristic deftness and eloquence’ Financial Times For decades Marie Curie was the only woman in the room at international scientific gatherings, and despite constant illness she travelled far and wide to share the secrets of radioactivity, a term she coined. She is still the only person to win a Nobel Prize in two scientific fields.Her ingenuity extended far beyond the laboratory walls; grieving the death of her husband, Pierre, she took his place as professor of physics at the Sorbonne, devotedly raised two daughters, drove a van she outfitted with X-ray equipment to the front lines of World War I, befriended Albert Einstein and inspired generations of young women to pursue science as a way of life.Approaching Marie Curie from a unique angle, Sobel navigates her remarkable discoveries and fame alongside the women who became her legacy – from Norway’s Ellen Gleditsch and France’s Marguerite Perry, who discovered the element francium, to her own daughter, Irene, a Nobel Prize winner in her own right. The Elements of Marie Curie deftly illuminates the trailblazing life and enduring influence of one of the most consequential figures of our time. ‘A lucid, literate biography, celebrating a scientific exemplar who, for all her fame, deserves to be better known’ Kirkus ‘As expected from a Pulitzer Prize finalist, Sobel writes beautifully and with clarity about the science that Curie specialised in, making clear the achievements that her lab brought about’ Daily Mail ‘This is an essential read, capturing both [Curie's] genius and her legacy’ New Scientist ‘Sobel’s book is a luminous and illuminating contribution to the cause’ Literary Review

Dava Sobel, acclaimed and bestselling author of Longitude, chronicles the life and work of the most famous woman in the history of science – and the untold story of the young women who trained in her laboratory. ‘A fresh and feminist study of the pioneering Nobel laureate reveals her impact on the women she mentored and set on the path to prominence’ Observer ‘It is a novel lens through which to view Curie’s story, and Sobel paints her tale with characteristic deftness and eloquence’ Financial Times For decades Marie Curie was the only woman in the room at international scientific gatherings, and despite constant illness she travelled far and wide to share the secrets of radioactivity, a term she coined. She is still the only person to win a Nobel Prize in two scientific fields.Her ingenuity extended far beyond the laboratory walls; grieving the death of her husband, Pierre, she took his place as professor of physics at the Sorbonne, devotedly raised two daughters, drove a van she outfitted with X-ray equipment to the front lines of World War I, befriended Albert Einstein and inspired generations of young women to pursue science as a way of life.Approaching Marie Curie from a unique angle, Sobel navigates her remarkable discoveries and fame alongside the women who became her legacy – from Norway’s Ellen Gleditsch and France’s Marguerite Perry, who discovered the element francium, to her own daughter, Irene, a Nobel Prize winner in her own right. The Elements of Marie Curie deftly illuminates the trailblazing life and enduring influence of one of the most consequential figures of our time. ‘A lucid, literate biography, celebrating a scientific exemplar who, for all her fame, deserves to be better known’ Kirkus ‘As expected from a Pulitzer Prize finalist, Sobel writes beautifully and with clarity about the science that Curie specialised in, making clear the achievements that her lab brought about’ Daily Mail ‘This is an essential read, capturing both [Curie's] genius and her legacy’ New Scientist ‘Sobel’s book is a luminous and illuminating contribution to the cause’ Literary Review

A subject index and a comprehensive index of radionuclides considered in all parts and supplements of ICRP Publication 30.

This report is a revision of ICRP Publication No 13. The recommendations it contains apply to the protection of pupils/students from ionizing radiation. They apply mainly to the teaching of natural science at secondary level, but they may be adapted to some forms of tertiary education.

This report provides guidance on the application of the ICRP system of radiological protection to prolonged exposure situations effecting members of the public. It addresses the general application of the Commission′s system to the control of prolonged exposures resulting from practices and to the undertaking of interventions in prolonged exposure situations. Additionally, it provides recommendations on generic reference levels for such interventions. The report also considers some specific situations and discusses a number of issues that have been of concern, namely: natural radiation sources that may give rise to high doses; the restoration and rehabilitation of sites where human activities involving radioactive substances have been carried out; the return to `normality′ following an accident that has released radioactive substances to the environment; and the global marketing of commodities for public consumption that contain radioactive substances. Annexes provide some examples of prolonged exposure situations and discuss the radiological protection quantities, radiation-induced health effects and aspects of the Commission′s system of radiological protection relevant to prolonged exposure.

Percutaneous Surgery of the Upper Urinary Tract: Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format. Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology. All chapters describe the most recent techniques, review the latest results, and analyze the most modern technologies.

In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic minimally invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine.

As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides quick references and over 4000 images that are appropriate for fellows as well as those teaching in the field.

Offers review content for urologists in training and "refresher� content for experts in endourology Explores new surgical techniques and technology through review-level content and extensive images of pathologies Includes over 500 images per volume; images taken from more than 4000 endourologic procedures performed annually at the editor's hospital

Nuclear cardiac imaging refers to cardiac radiological diagnostic techniques performed with the aid of radiopharmaceuticals, which are perfused into the myocardium as markers. These imaging studies provide a wide range of information about the heart, including the contractility of the heart, the amount of blood supply to the heart and whether parts of the heart muscle are alive or dead. This is essential information for cardiologists, and nuclear imaging has become an increasingly important part of the cardiologist's armamentarium. Chapters in Nuclear Cardiac Imaging cover historical, technical and physiological considerations, diagnosis and prognosis, conditions other than Coronary Artery Disease (CAD), advanced cardiac imaging, and challenges and opportunities. New to the sixth edition are key point summaries at the start of each chapter, clinical cases with videos, and a question and answer chapter on practical issues. This volume is ideal for nuclear cardiologists in training and nuclear clinicians alike who are searching for quick answers to important clinical and technical questions.

Neurological history claims its earliest origins in the 17th century with Thomas Willis's publication of Anatomy of the Brain, coming fully into fruition as a field in the late 1850s as medical technology and advancements allowed for in depth study of the brain. However, many of the foundations in neurology can find the seed of their beginning to a time much earlier than that, to ancient Greece in fact. Neurological Concepts in Ancient Greek Medicine is a collection of essays exploring neurological ideas between the Archaic and Hellenistic eras. These essays also provide historic, intellectual, and cultural context to ancient Greek medical practice and emphasizing the interest in the brain of the early physicians. This book describes source material that is over 2,500 years old and reveals the observational skills of ancient physicians. It provides complete translations of two historic Hippocratic texts: On the Sacred Diseases and On the Wounds of the Head. The book also discusses the Hippocratic Oath and the modern applications of its meaning. Dr. Walshe connects this ancient history, usually buried in medical histories, and shows the ancient Greek notions that are the precursors of our understanding of the brain and nervous system.

The neuron doctrine, first formulated in 1891, states that the brain is constructed of individual neurons, organized into functioning circuits that mediate behavior. Above all else, this is the main concept that underlies all of modern neuroscience. This 25th Aniversary Edition of The Foundations of the Neuron Doctrine explains how this theory was the product of an explosion of histological studies and vigorous debates near the end of the nineteenth century by an extraordinary group of scientists, most importantly the leading figure of the time, Santiago Ramon y Cajal of Spain, and includes the foremost nervous system investigators of many countries, such as Albrecht Kolliker, Sigmund Freud, Wilhelm His, August Forel, Fritdjof Nansen and Gustav Retzius. The neuron doctrine explains how these eminent scientists used a selective nerve cell stain invented by Camillo Golgi of Italy and followed him in describing the fabulous branching patterns of nerve cells, providing strong evidence that the cells interact as individual units to form circuits. This work also describes how this view was opposed by Golgi, who maintained that the nerve cells form syncytial networks. Studies in the 1950s appeared resoundingly to confirm the nerve cell as an individual unit, as embodied in the neuron doctrine, which became the basis for the rise of concepts of normal and disordered neural function in the remaining 20th century. This 25th Anniversary Edition concludes by discussing how recent studies are showing a much greater degree of complexity in neuronal organization, so that the debate of neuron versus network is again coming to the fore of neuroscience research. Unique to this anniversary edition is the inclusion of commentaries by distinguished leaders in the neurosciences on the continuing relevance of the neuron doctrine for modern studies of the brain at all levels, from genes and molecules to microcircuits, neural networks, and behavior.

As functional imaging becomes increasingly important in radiology, practitioners in a wide range of disciplines need to understand more about the quantitive aspects of physiology and pathophysiology. In straightforward language, this book integrates the principles and mathematics of measurements with physiological systems to which the quantitive problems are applied. Although there is an emphasis on clinical management with radionuclides and quantitive procedures in nuclear medicine, this book has been written with all practitioners in mind and also therefore embraces techniques based on non-radioactive indicators, including contrast agents used in CT, MRI, and ultrasound. Starting from basic mathematics, the book describes the measurement of fundamental physiological variables, like transit time, clearance, and blood flow, and goes on to cover the perpheral circulation and microvascular solute transfer, the pharmacokinetics of agents routinely used in nuclear medicine, as well as scintillation detectors, data processing, and quantification. In separate chapters, measurements in the heart, lung, gastrointestinal tract, liver, blood, genitourinary tract, brain, and skeleton are discussed, and the book finishes with a chapter on questions and worked answers.

The European Society of Cardiology publications are key reference works authored and edited by leading international experts. Aligned with the ESC Core Curriculum, the ESC suite of publications are optimally placed for training and accreditation in cardiovascular medicine and related specialties.Our extensive line-up of publications is anchored by the groundbreaking ESC CardioMed: an online-only work comprised of nearly 70 sections, with over 1000 chapters, and authors from around the globe. Every publication is peer reviewed and supported by evidence-based research, reflects current ESC guidelines, the educational syllabus, task force reports, and the scientific statements that guide current clinical practice.Digital excellence at the heart of cardiology All ESC publications are available in multiple outputs, with an increased emphasis of online updates to meet the needs of todays user. Oxford University Press shares the ESC mission to reduce the burden of cardiovascular disease through this publishing partnership.

Biomedical ultrasonics is inherently interdisciplinary, involving mechanics, electrical engineering, physics, biology, and medicine. As such, it can be an extraordinarily difficult subject to cover in one book. Drawn from years of class notes, student interaction and personal experience, Foundations of Biomedical Ultrasound does just that. It covers the fundamental engineering behind ultrasound equipment, properties of acoustic wave motion, the behaviour of waves in various media, non-linear waves and the creation of images. The most comprehensive book on the subject, Foundations of Biomedical Ultrasound is an indispensible reference for any medical professional working with ultrasound imaging, and a comprehensive introduction to the subject for students. The book consists of ten chapters that bridge the spectrum from the fundamental properties of wave propagation through to clinical systems. The first four chapters describe linear and nonlinear propagation, and methods for calculating the field produced by transducers of various designs. A number of problems designed to test the reader's understanding, well-suited for formal class assignments, accompany these chapters. The topics of ultrasound scattering, and transducer design are addressed in chapters 5 and 6. The final four chapters addess methods of imaging and flow measurement. Some 350 drawings, graphs, sketches and colour images have been used. These, together with many tables, have been used to illustrate the various topics covered; a substantial portion of which are appearing for the first time in print.

Perhaps the most important achievements in the field of epileptology in the past two decades have been in the neuroimaging and genetic breakthroughs as applied to patients with epilepsy. Indeed, neuroimaging has become a vital part in the study of epilepsy, affecting broad aspects of the disorder ranging from diagnosis and classification to treatment and prognosis. Neuroimaging in epilepsy encompasses many different approaches that have reached various levels of expertise across epilepsy centers worldwide. This book discusses every imaging modality used to gather information on epilepsy. Each technique is described by world experts and epilespy centers worldwide.

A companion to the 6th edition of Nuclear Cardiac Imaging, this text offers readers additional case examples and figures not included in the related textbook as well as a concise option for readers seeking a case book for quick review for examination preparation or assistance with image interpretation. Rather than focusing on theoretical explanations, the atlas provides high-yield, rapid imaging support with a particular emphasis on cases with angiography, echocardiography, and other imaging correlations. With a variety of cases and multiple-choice self-assessment questions along with a comprehensive multiple-choice exam to be taken upon completion of the text, the Companion Atlas will solidify readers' knowledge and ranges in levels of difficulty, including those intended to challenge even the most expert reader.

Low back pain affects almost everyone at some point, and many people struggle with pain or limitations despite multiple attempts at treatment. Current spine care is plagued by variability, over-medicalization of biopsychosocial problems, inequity, and an over-emphasis on interventional and surgical care. Guidelines focused on the short-term management of acute low back pain are generally not followed and have limited applicability. Non-specific and poorly verified diagnoses further confound clinical care. The reality is that low back pain is a chronic recurrent problem for most individuals, and care should therefore be directed toward long-term management and optimization of life and function.Low Back Pain recognizes that all low back pain conditions are not created equally and focuses on effective treatments for a diverse set of low back pain issues. Part of the” What Do I Do Now?: Pain Medicine” series this text provides concise, evidence-based, and practical guidance on the management of back pain and related spinal disorders. With practical information on effective front-line care for those with low back pain, the cases in this book reflect common or illustrative clinical presentations and a solid framework for evaluating those with low back pain, clarity on specific conditions, and a critical approach to diagnosis and treatment.

Radioisotope therapy is an internal form of radiation used to treat cancer; it may be administered orally or intravenously and represents the nearest treatment option to the 'magic bullet', specifically targeting sites of disease whilst sparing surrounding normal tissues. Radioisotope therapy has an important role to play in modern medicine, particularly in the treatment of thyroid disease, neuroendocrine tumours, bone metastasis and non-Hodgkin's lymphoma. It is found in both the diagnostic setting and in therapy, but recently there has been a renaissance in the application of radioisotope unsealed sources in therapeutic indications. It is an active area of research, with the quest for new compounds that will be specific for therapeutic targets.This book is an essential, practical guide to the use of radioisotope therapy, and also includes the background and developmental biology which underpins its use. Individual tumours and diseases are explored, with specific focus given to radioisotope treatment options. The barriers to radioisotope therapy, such as ease of access, acquisition of radioisotopes, radiation protection regulations, and cost are also discussed. ABOUT THE SERIESRadiotherapy remains the major non-surgical treatment modality for the management of malignant disease, with over 50% of patients receiving treatment at some time during the management of their malignant disease. It is based on the application of the principles of applied physics, radiobiology, and tumour biology to clinical practice. Each volume in this series takes the reader through the basic principles of different types of radiotherapy, and then develops these by individual sites. This series of practical handbooks are aimed at physicians both training and practising in radiotherapy, as well as medical physicists, dosimetrists, radiographers and senior nurses.

Readable, practical and concise, Nuclear Cardiology is a self-contained guide to this cardiac imaging subspecialty. Including both technical and clinical aspects, it provides a foundation of essential knowledge common to practitioners from any background.This title covers radiation physics, biology and protection, and addresses all areas of imaging including the design and operation of the gamma camera (including solid-state cameras), single photon emission computed tomography (SPECT) acquisition and processing, and image interpretation and writing of reports. Stress testing and radiopharmaceuticals are explained in detail, as is the evidence-base underpinning myocardial perfusion scintigraphy. Newer radionuclide imaging techniques are well-covered (e.g. phosphate scintigraphy in cardiac amyloidosis), as is the expanding field of cardiac positron emission tomography (PET).Fully updated with coverage of new indications for gamma camera imaging, increased focus on attenuation correction and SPECT-CT and detail on the design use and clinical implications of solid-state gamma cameras throughout, this second edition of the essential text for nuclear cardiology trainees and practitioners is fully illustrated with colour plates to aid clinical practice. Presented in the bestselling Oxford Specialist Handbook format, Nuclear Cardiology provides core knowledge for those training in the subspecialty, whether at a basic or advanced level or from a medical or technical background, and is a key resource for those seeking to accredit in the subspecialty.

MCQs for First FRCR offers the most comprehensive coverage of the topics covered in the new First Fellowship of Royal College of Radiology (FRCR) examination, which includes newly-added topics such as ultrasound and magnetic resonance. Led by specialist trainees with recent exam experience and contributions from experienced senior consultants and examiners, this book offers not only relevant content and valuable insights, but also visually enhanced answer sections (including diagrams and tables) that aim to improve and enhance understanding of key concepts in medical physics and radiation protection.Each chapter includes up to forty multiple choice questions covering each area of the exam. Each question and answer includes explanations and further reading.

Medical imaging now plays a major role in diagnosis, choice of therapy, and follow-up. However, patients are often intimidated by the multiple imaging modalities available, the indications for their use, the imposing equipment, what the examinations are like and how long they last, and the advantages and disadvantages of various procedures. This book is designed to provide explanations for these and other issues in order to relieve some of the anxiety related to medical imaging studies.

Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on the replacement of lost or damaged function, usually through the suppression of surviving neural activity and the application of mechanical assistive devices. Restorative Neurology of Spinal Cord Injury offers a different and novel approach. Focusing on the spinal cord and its role in motor control, the book details the clinical and neurophysiological assessment process and methods developed throughout the past half century by basic and clinical scientists. Then, through the use of specialized clinical and neurophysiological testing methods, conduction and processing performed within the surviving neural circuitry is examined and characterized in detail. Based on the results of such assessment, treatment strategies, also described in this book, are applied to augment, rather than replace, the performance of surviving neural circuitry and improve the functional capacity of people who have experienced injury to their spinal cords.

In 194 cases featuring over 450, high-quality images, Nuclear Medicine and PET/CT Cases provides a succinct review of clinically relevant cases covering the full range of nuclear medicine. Cases are grouped into sections including: Nuclear CNS Imaging, Nuclear Inflammation/Infection Imaging, Ventilation/Perfusion Lung Scintigraphy, Pediatric Nuclear Medicine, Cardiac Imaging, Bone Scintigraphy, PET/CT in Oncology, General Oncologic Imaging, Thyroid and Parathyroid, Radionuclide Therapy and Pre-Therapy Evaluation, Liver, Spleen and Biliary Tract, Gastrointestinal Tract, Renal Scintigraphy. Part of the Cases in Radiology series, this book follows the easy-to-use format of question and answer in which the patient history is provided on the first page of the case, and radiologic findings, differential diagnosis, teaching points, next steps in management, and suggestions for furthering reading are revealed on the following page. This casebook is an essential resource for radiology residents and practicing radiologists alike.

Chest Imaging presents a comprehensive review of thoracic pathologies commonly encountered by practicing radiologists and residents in training. The volume covers topics including: Common Abnormalities, Emergency Radiology, Pleural Disease, Infections, Neoplasms, and Airway Disease. Each section begins with an overview chapter that orientes the reader to the concerns and issues related to imaging in the specific anatomic region or category. Part of the Rotations in Radiology series, this book offers a guided approach to imaging diagnosis with examples of all imaging modalities complimented by the basics of interpretation and technique and the nuances necessary to arrive at the best diagnosis. Each chapter contains a targeted discussion of a pathology which reviews the definition, clinical features, anatomy and physiology, imaging techniques, differential diagnosis, clinical issues, key points, and further reading. This book is a must-read for residents and practitioners in radiology seeking refreshing on essential facts and imaging abnormalities in thoracic imaging.

In contrast to most anatomic radiographic imaging techniques, nuclear medicine permits real time, non-invasive imaging of human physiology and pathophysiology and also allows for exquisite targeting of disease with therapeutic radiology. To open this window to the processes of human disease, one must first understand the physical processes behind radioactive decay and emission, as well the principles of radiation detection. Practical Nuclear Medicine Physics provides residents and practitioners in nuclear medicine and radiology a readable explanation of the physics concepts underpinning nuclear imaging and how they impact the utilization and interpretation of those images. Following a brief introductory section, the book provides numerous case examples, illustrating various imaging artifacts and pitfalls that can be recognized and remedied with a solid understanding of the physics behind the procedure. Understanding and applying the physics behind nuclear medicine is essential to maximizing not only diagnostic and therapeutic accuracy for providing optimal patient care, but "Practical Physics" is a required portion of radiology residency education and a designated area of the board exams.

After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. Even as the atomic bomb became the focus of Cold War anxiety, radioisotopes represented the government's efforts to harness the power of the atom for peace—advancing medicine, domestic energy, and foreign relations. In Life Atomic, Angela N. H. Creager tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology. Government-produced radioisotopes provided physicians with new tools for diagnosis and therapy, specifically cancer therapy, and enabled biologists to trace molecular transformations. Yet the government's attempt to present radioisotopes as marvelous dividends of the atomic age was undercut in the 1950s by the fallout debates, as scientists and citizens recognized the hazards of low-level radiation.Creager reveals that growing consciousness of the danger of radioactivity did not reduce the demand for radioisotopes at hospitals and laboratories, but it did change their popular representation from a therapeutic agent to an environmental poison. She then demonstrates how, by the late twentieth century, public fear of radioactivity overshadowed any appreciation of the positive consequences of the AEC's provision of radioisotopes for research and medicine.

Mankind has evolved in a sea of radiation. We have been bombarded constantly by X rays, y rays, UV rays, and particulate radiations from outer space, and by terrestrial radiations from the ground we walk on, from our building materials, and from our own bodies. Recently, we have become increasingly subjected to man-made radiations, especially from the medical and defense industries. All of these radiations are capable of affecting us biologically, both to our benefit and to our detriment. This book provides a thorough review of the physical and biological dosimetry of these radiations. It is targeted to those health professionals who are concerned with understanding the mechanisms fundamental to the biological action of ionizing radiation or who are involved in the application, measurement, or treatment of the effects of such radiations. The first chapter, on "Bioeffect Dosimetry in Radiation Therapy," should be of special interest to anyone involved in the treatment of cancer by radiation. It includes a brief review of the history of the manipulation of time-dose parameters in order to improve therapeutic benefit, and an up-to-date analysis of time-dose relationships designed for use in fractionated radiotherapy and brachytherapy. This is followed by two chapters reviewing and comparing national and international protocols for the precise measurement of photon and electron radiations in therapy. These chapters should be invaluable to radiation physicists responsible for treatment machine calibrations.