Practical Diagnostic Surgical and Cytopathology of the Pancreas and Biliary Tract

Vikram Deshpande, an internationally recognized gastrointestinal and pancreatic pathologist, has authored over 300 peer-reviewed papers. Renowned for his exceptional teaching skills, he excels in simplifying complex topics. His innovative teaching approach incorporates brief, informative videos. He is an award-winning educator and actively engages with the medical community on Twitter (@vik_deshpandeMD) and YouTube https://www.youtube.com/c/vikramdeshpandePathology Karen Pinto is a cancer pathologist at the Kuwait Cancer Control Center whose interest in pathology extends beyond the microscope. With a love for visual storytelling, she attempts to transform dense medical information into simple yet artistic infographics. Likewise, she enjoys deconstructing complex medical topics into captivating videos which she shares on social media, accessible to a diverse audience. Runjan Chetty is a gastrointestinal and pancreatic pathologist with additional interests in digital pathology and AI development. He has over 450 publications in per-reviewed journal and a co-author of Leong's Manual of Immunohistology (Cambridge University Press, 2022). He has held chairs of Pathology at the University of Natal (South Africa), University of Glasgow and personal chairs at the Universities of Toronto and Oxford. He was program medical director and Pathologist in Chief at University Health Network, Toronto, Canada. Munita Bal is Professor of Pathology at Tata Memorial Centre and specializes in Head and Neck and Gastrointestinal Pathology. With twenty-three years of teaching experience, she contributes to WHO tumour classifications, ICCR datasets, and the National Cancer Grid. Dr Bal has numerous publications and lectures, both nationally and internationally.

• Section 1. Introduction to pancreatic cytopathology and histopathology; 1. Anatomy of the pancreas, bile duct, and the Ampulla of Vater; 2. Histology of pancreas; 3. Cytology of the normal pancreas; 4. Introduction to cytology techniques; 5. Introduction to the gross evaluation of pancreatic solid and cystic lesions; 6. WHO cytology system for classifying pancreatic neoplasms; Section 2. Inflammatory lesions of the pancreas and mimics of neoplasia; 7. Autoimmune pancreatitis; 7.1. Autoimmune pancreatitis: introduction; 7.2. AIP Type 1; 7.3. AIP Type 2; 7.4. Autoimmune pancreatitis and other mass-forming causes of pancreatitis: cytology; 7.5. Chronic pancreatitis; 7.6. Groove pancreatitis; 7.7. Follicular pancreatitis; 7.8. Acute pancreatitis; 7.9. Hereditary pancreatitis; 7.10. Intrapancreatic spleen; 7.11. Pseudolipomatous hypertrophy; 7.12. Obstructive pancreatitis; 7.13. Systemic inflammatory diseases of the pancreas; Section 3. Solid neoplasms of the pancreas; 8. Pancreatic intraepithelial neoplasia; 9. Carcinomas; 9.1. Pancreatic ductal adenocarcinoma: histology and cytology; 9.2. Adenosquamous carcinoma; 9.3. Colloid carcinoma; 9.4. Large duct variant of pancreatic adenocarcinoma; 9.5. Other histological variants of pancreatic ductal adenocarcinoma; 9.6. Medullary carcinoma and MSI; 9.7. Hepatoid carcinoma; 9.8. Undifferentiated carcinoma; 9.9. Undifferentiated carcinoma with osteoclast giant cells; 9.10. Cytological features of variants of pancreatic carcinoma; 10. Neuroendocrine neoplasms; 10.1. Introduction to pancreatic neuroendocrine neoplasms; 10.2. Non-functional pancreatic neuroendocrine tumour; 10.3. PanNET Cytology; 10.4. Functional pancreatic neuroendocrine tumours; 11. Pancreatic neuroendocrine carcinoma; 12. Mixed neuroendocrine–non-neuroendocrine neoplasm; 13. Acinar cell carcinoma; 13.1. Mixed acinar endocrine carcinoma; 14. Pancreatoblastoma; 15. Haematological malignancies; 16. Metastatic neoplasms to pancreas; 17. Mesenchymal neoplasms; 17.1. Perivascular Epithelioid Cell Neoplasm (PEComa); 18. Frozen section pathology of pancreas; 19. Neoadjuvant therapy for pancreatic neoplasms; 20. Non-neoplastic histological changes seen in pancreatic resections; Section 4. Cystic neoplasms of the pancreas; 21. Approach to cystic pancreatic lesions; 21.1. Clinico-Radiologic approach to cystic lesions of the pancreas; 21.2. Chemical analysis of cystic fluid; 21.3. Molecular approach to pancreatic cyst fluid; 21.4. Management of pancreatic cystic lesions; 22. Cystic neoplasms; 22.1. Intraductal papillary mucinous neoplasm (IPMN); 22.2. Intraductal Oncocytic Papillary Neoplasm (IOPN); 22.3. Intraductal Tubulopapillary Neoplasm (ITPN); 22.4. Mucinous cystic neoplasm; 22.5. Solid pseudopapillary neoplasm; 22.6. Serous cystadenoma; 22.7. Acinar cystic transformation of the pancreas; 22.8. Solid tumors that may present as cystic lesions; 22.9. Simple mucinous cyst; 23. Mimics of cystic pancreatic neoplasms; 23.1. Pseudocyst; 23.2. Lymphangioma; 23.3. Lymphoepithelial cyst; 23.4. Squamoid cyst; 23.5. Mature cystic teratoma (Dermoid cyst); 23.6. Intrapancreatic spleen and epidermoid cyst in intrapancreatic ectopic spleen; 23.7. Enterogenous cyst, ciliated foregut cyst, duplication cyst; 23.8. Retention cyst; Section 5. Inflammatory and neoplastic diseases of the biliary tract; 24. Cytological features of biliary neoplasia; 25. Molecular approach to biliary cytology; 26. Neoplasms of bile duct; 26.1. Bile Duct Adenoma; 26.2. Biliary adenofibroma; 26.3. Biliary Intraepithelial Neoplasia (BilIN); 26.4. Intraductal papillary neoplasm of bile duct; 26.5. Mucinous cystic neoplasm of the liver and bile duct;26.6. Bile duct carcinoma (cholangiocarcinoma); 26.7. Neuroendocrine neoplasms of Bile duct; 27. Mimics of bile duct neoplasia; 27.1. IgG4-related sclerosing cholangitis; 27.2. Follicular cholangitis; 28. Epithelial neop