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Nyhet
The It/OT Handbook: The Practitioner's Guide to It and OT Cooperation in Manufacturing: From Silos to Sustainable Digitalization
AvDavid Ariens,Willem Van Lammeren
Häftad, Engelska, 2026
312 kr
Skickas inom 3-6 vardagar
Molecular Pharmacology V3
The Model of Action of Biology Active Compounds
AvE.J. Ariens
E-bok
PDF, Engelska, 2012
739 kr
Läs direkt efter köp
Molecular Pharmacology: The Model of Action of Biologically Active Compounds, Volume 1 discusses the mode of action of bioactive compounds on a molecular level. This book reviews the processes that control the uptake of drugs, their diffusion through tissues, as well as their metabolism and excretion. Comprised of three sections, this volume starts with an overview of the different aspects of drug distribution and metabolism. This text then examines the totality of intermolecular processes or reactions between drug and receptor molecules, which is known as drug-receptor interaction. Other chapters explore the actions of various pharmacodynamic agents, including hormones and substances with selective toxicity, auxins, and odorants. This book discusses as well the ways in which the actions of drugs combine with the tissues and act upon themselves. The final chapter deals with the complicated types of relations between stimulus and effect. Pharmacologists and researchers will find this book useful.
Molecular Pharmacology V2
The Model of Action of Biology Active Compounds
AvE.J. Ariens
E-bok
PDF, Engelska, 2012
739 kr
Läs direkt efter köp
Molecular Pharmacology: The Mode of Action of Biologically Active Compound, Volume II presents the mode of action of bioactive compounds on a molecular level, which concerns a wide variety of pharmacodynamic agents. This book discusses in detail the actions of odorants, the chemotherapeutics used in the fight against cancer, as well as the interactions of substrates and enzymes. Comprised of three parts, this volume starts with an overview of the mode of action of odorants and explores the anatomical and histochemical location of the receptors. This text then explains the molecular processes that are involved olfaction. Other chapters consider the different types of chemotherapeutics used against cancer, such as the antimetabolites and radiomimetics. The final chapter deals with the structure of chemical groups that constitute the receptors and the active sites on the enzymes. This book is a valuable resource for pharmacologists and clinical researchers interested in the study of bioactive compounds.
Lawyer's Conscience
A History of American Lawyer Ethics
AvMichael S. Ariens
Häftad, Engelska, 2023
428 kr
Skickas inom 10-15 vardagar
In 1776, Thomas Paine declared the end of royal rule in the United States. Instead, “law is king,” for the people rule themselves. Paine’s declaration is the dominant American understanding of how political power is exercised. In making law king, American lawyers became integral to the exercise of political power, so integral to law that legal ethics philosopher David Luban concluded, “lawyers are the law.”American lawyers have defended the exercise of this power from the Revolution to the present by arguing their work is channeled by the profession’s standards of ethical behavior. Those standards demand that lawyers serve the public interest and the interests of their paying clients before themselves. The duties owed both to the public and to clients meant lawyers were in the marketplace selling their services, but not of the marketplace.This is the story of power and the limits of ethical constraints to ensure such power is properly wielded. The Lawyer’s Conscience is the first book examining the history of American lawyer ethics, ranging from the mid-eighteenth century to the “professionalism” crisis facing lawyers today.
Lawyer's Conscience
A History of American Lawyer Ethics
AvMichael S. Ariens
E-bok
Engelska, 2023
589 kr
Läs direkt efter köp
In 1776, Thomas Paine declared the end of royal rule in the United States. Instead, “law is king,” for the people rule themselves. Paine’s declaration is the dominant American understanding of how political power is exercised. In making law king, American lawyers became integral to the exercise of political power, so integral to law that legal ethics philosopher David Luban concluded, “lawyers are the law.”
American lawyers have defended the exercise of this power from the Revolution to the present by arguing their work is channeled by the profession’s standards of ethical behavior. Those standards demand that lawyers serve the public interest and the interests of their paying clients before themselves. The duties owed both to the public and to clients meant lawyers were in the marketplace selling their services, but not of the marketplace.
This is the story of power and the limits of ethical constraints to ensure such power is properly wielded. The Lawyer’s Conscience is the first book examining the history of American lawyer ethics, ranging from the mid-eighteenth century to the “professionalism” crisis facing lawyers today.
Lawyer's Conscience
A History of American Lawyer Ethics
AvMichael S. Ariens
Inbunden, Engelska, 2022
703 kr
Skickas inom 10-15 vardagar
In 1776, Thomas Paine declared the end of royal rule in the United States. Instead, “law is king,” for the people rule themselves. Paine’s declaration is the dominant American understanding of how political power is exercised. In making law king, American lawyers became integral to the exercise of political power, so integral to law that legal ethics philosopher David Luban concluded, “lawyers are the law.”American lawyers have defended the exercise of this power from the Revolution to the present by arguing their work is channeled by the profession’s standards of ethical behavior. Those standards demand that lawyers serve the public interest and the interests of their paying clients before themselves. The duties owed both to the public and to clients meant lawyers were in the marketplace selling their services, but not of the marketplace.This is the story of power and the limits of ethical constraints to ensure such power is properly wielded. The Lawyer’s Conscience is the first book examining the history of American lawyer ethics, ranging from the mid-eighteenth century to the “professionalism” crisis facing lawyers today.
Lone Star Law
A Legal History of Texas
AvMichael Ariens
Inbunden, Engelska, 2011
483 kr
Skickas inom 3-6 vardagar
Michael Ariens proves that no state possesses a richer or more surprising legal history than Texas. In narrative as engaging as it is accessible, he has produced an overarching consideration of Lone Star law and legal culture—something notably missing in other Texas histories. After taking readers chronologically from early settlement through 1920, Ariens focuses on particular areas of Texas law, including property, family, business, criminal, and civil harms (tort), and on the history of Texas's legal profession itself. Through illuminating and utterly Texan particulars, Ariens helps us understand a place at once southern and western, Spanish and Mexican, republic and state.
Dissertation Sur Les Semi-ariens, Dans Laquelles On DÃ(c)fend La Nouvelle Edition De S. Cyrille De Jerusalem Contre Les Auteurs Des MÃ(c)moires De TrÃ(c)voux...
AvPrudent Maran
Inbunden, Franska, 2025
349 kr
Skickas inom 5-8 vardagar
Dissertation Sur Les Semi-ariens, Dans Laquelles On DÃ(c)fend La Nouvelle Edition De S. Cyrille De Jerusalem Contre Les Auteurs Des MÃ(c)moires De TrÃ(c)voux...
AvPrudent Maran
Häftad, Franska, 2025
196 kr
Skickas inom 5-8 vardagar
Mantras and Affirmations Coloring Book for Ariens
AvBridget Owens,Bryn Maycot
Häftad, Engelska, 2018
170 kr
Skickas inom 5-8 vardagar
Physico-Chemical Aspects of Drug Action
Proceedings of the Third International Pharmacological Meeting
AvE. J. Ariens
E-bok
PDF, Engelska, 2017
831 kr
Läs direkt efter köp
Physico-Chemical Aspects of Drug Action, Volume 7 covers topics on drug kinetics and the overall physicochemical properties of the drug in relation therewith, and the physicochemical aspects of the drug-receptor interaction, putting emphasis on receptor mechanisms and specific properties required for certain types of drugs in this respect. The book starts with some contributions dealing with various general aspects of drug kinetics followed by some contributions dealing with the relationship between certain physicochemical properties of drug molecules and their action. The text describes the pharmacokinetics and dose-concentration relationships; the time course of the biological response to drugs; and the empirical equations for correlating biological efficiency of organic compounds. The text also describes molecular basis for the action of chemotherapeutic drugs; the structure-activity studies on sulphonamides; and the water extrusion hypothesis. The mathematical treatment of two-point attachment between drug and receptor; the molecular properties and biological activity of catecholamines and certain related compounds; and the structure-activity relationships of diarylcarbinolethers are also considered. The book further tackles quantum mechanically-derived electronic distributions in the conformers of 2-pam; and the molecular basis for the action of certain drugs in the central nervous system. Pharmacologists and chemists will find the book invaluable.
Drug Design
Medicinal Chemistry: A Series of Monographs, Vol. 2
AvE. J. Ariens
E-bok
PDF, Engelska, 2013
1 076 kr
Läs direkt efter köp
Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of cholinesterases. The text also describes the design of reactivators for irreversibly blocked acetylcholinesterase; drug design based on the inhibition of protein synthesis in the context of susceptible enzymic reactions; as well as the role of enzymes and their synthesis as a target for antibiotic action. The rational design of antiviral agents; the design of penicillin; the design of peptide hormone analogs; as well as the advances in the design of diuretics are also considered. The book further tackles the design of biologically active steroids; the rational elements in the development of superior neuromuscular blocking agents; and the design of tumor-inhibitory alkylating drugs. Pharmacologists, chemists, and people involved in drug design will find the book invaluable.
Drug Design
Medicinal Chemistry: A Series of Monographs, Vol. 3
AvE. J. Ariens
E-bok
PDF, Engelska, 2013
1 076 kr
Läs direkt efter köp
Drug Design, Volume III covers the mode of action of biologically active compounds. The book discusses microbial transformations that have been used in the preparation of drugs or closely related substances; the use of linear free energy parameters and other experimental constants in structure-activity studies; and the mode of action of anticoagulants structurally and functionally related to vitamin K. The text also describes the design of beta-blocking drugs, biologically active acridines, local anesthetics, and insect chemosterilants. The molecular approach for designing inhibitors to enzymes involved in blood clotting is also considered. Chemists, pharmacologists, and people involved in drug design.
Drug Design
Medicinal Chemistry: A Series of Monographs, Vol. 4
AvE. J. Ariens
E-bok
PDF, Engelska, 2013
1 053 kr
Läs direkt efter köp
Drug Design, Volume IV covers the pharmaceutical phase of drug action, with emphasis on those aspects that are of importance in the design of optimally effective drug products. The book discusses biopharmaceutics as a basis for the design of drug products; the types and pharmacokinetics of peroral prolonged action dosage forms and parenteral prolonged action forms; and the design of topical drug products. The text also describes physical-chemical parameters which affect the bioavailability of topical drug products; the design of sunscreen preparations; as well as the clinical application of litholytic agents, which are preventive and curative drugs for nephrolithiasis. The design of biologically active nucleosides and of insecticidal chlorohydrocarbon derivatives is also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.
Drug Design
Medicinal Chemistry: A Series of Monographs, Vol. 5
AvE. J. Ariens
E-bok
PDF, Engelska, 2013
807 kr
Läs direkt efter köp
Drug Design, Volume V covers the fundamental approaches to the development of bioactive compounds. The book discusses the utilization of operational schemes for analog synthesis in drug design; the design of enzyme inhibitors (transition state analogs); and the significance of structure-absorption-distribution relationships for drug design. The text describes the role of charge-transfer processes in the action of bioactive materials, as well as the approaches to the rational combination of antimetabolites for cancer chemotherapy. The physicochemical, quantum chemical, and other theoretical techniques for the understanding of the mechanism of action of central nervous system (CNS) agents, such as psychoactive drugs, narcotics, and narcotic antagonists and anesthetics, are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.
Drug Design
Medicinal Chemistry: A Series of Monographs, Vol. 6
AvE. J. Ariens
E-bok
PDF, Engelska, 2013
831 kr
Läs direkt efter köp
Drug Design, Volume VI covers practical approaches to the development of bioactive compounds, with focus on antiradiation agents, organ-imaging radiopharmaceuticals, X-ray contrast media, proteinase inhibitors, and pesticide formulations. The book discusses the chemical routes available for the synthesis of diphenhydramine derivatives, the biological activities, the relationships between structure and activity, and the phase of manipulation in the design of diphenhydramine derivatives. The text also describes the design of antiradiation agents, organ-imaging radiopharmaceuticals, and X-ray contrast media, as well as the rational approach to proteinase inhibitors. The chemical and physical methods of formulation of agricultural pesticides are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design and manufacture will find the book invaluable.
Drug Design
Medicinal Chemistry: A Series of Monographs, Vol. 7
AvE. J. Ariens
E-bok
PDF, Engelska, 2013
813 kr
Läs direkt efter köp
Drug Design, Volume VII covers the design of agents such as blood substitutes, pesticides derived from insect pheromones, and herbicides related to the auxin-type plant hormones. The book discusses the design of artificial blood substitutes and auxin-type herbicides; the use of insect pheromones as a basis for the development of more effective selective pest control agents; and the development and application of new steric substituent parameters in drug design. The text also describes the use of computer technology in drug design. Pharmacologists, chemists, biochemists, and people involved in drug design and manufacture will find the book invaluable.
Drug Design
Medicinal Chemistry: A Series of Monographs, Vol. 8
AvE. J. Ariens
E-bok
PDF, Engelska, 2013
813 kr
Läs direkt efter köp
Drug Design, Volume VIII covers a critical review and new extensions of quantitative methods in drug design, the design of particular types of agents, such as synthetic sweeteners, and selective ion binding compounds. The book discusses the advances in the methodology of quantitative drug design; the application of pattern recognition to drug design; and the design of controlled drug delivery systems. The text also describes the use of receptor binding as a tool in the development of new bioactive steroids; the design of synthetic sweeteners; and the prospective assessment of environmental effects of chemicals. The design of selective ion binding macrocyclic compounds and their biological applications are also encompassed. Chemists, pharmacologists, biochemists, and people involved in drug design and manufacture will find the book invaluable.
Drug Design
Medicinal Chemistry: A Series of Monographs, Vol. 10
AvE. J. Ariens
E-bok
PDF, Engelska, 2013
831 kr
Läs direkt efter köp
Drug Design, Volume X covers promising and current developments in drug design. The book discusses procedures as applied in the practice of drug design; the structural aspects of the structure-activity relationships of neuroleptics; and promising perspectives in the highly actual field of bioactive peptides. The text also describes the application of the dynamic systems analysis to the antihypertensive drug action; polymeric drug delivery systems; and the design of biocompatible polymers. The structure-activity relationships of insect repellents as a basis for the design of such agents, as well as the approaches to the multivariate data analysis in structure-activity relationships, which is an essential aspect of drug design, are also encompassed. Chemists, pharmacologists, bioengineers, and people involved in drug design and manufacture will find the book invaluable.
vigne et le vin chez les Sémites et les Ariens primitifs, application des travaux philologiques
AvGlaize
Häftad, Franska, 2018
157 kr
Skickas inom 5-8 vardagar
livre de Saint-Phébade contre les Ariens
AvPhébade
Häftad, Franska, 2022
222 kr
Skickas inom 5-8 vardagar
Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progres des recherches pharmaceutiques
AvF. Labhardt,E. J. Ariensm. fl.
E-bok
PDF, Engelska, 2013
707 kr
Läs direkt efter köp
Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques
AvR. G. Denkewalter,M. Tishlerm. fl.
Häftad, Engelska, 2012
568 kr
Skickas inom 10-15 vardagar
Seit dem Erscheinen des ersten Bandes sind sieben Jahre vergangen. und del' Herausgeber freut sich. del' Fachwelt hiermit den 10. Band iibergeben zu konnen. In diesel' Zeitspanne haben auf versehiedenen Gebieten del' Arzneimittelfor- schung wichtige. zum Teil umwalzende Entwicklungen stattgefunden; einzelne davon wurden in diesel' Reihe bereits behandelt. mit dem Resultat. daB die FORT- SCHRITTE DER AI{ZNEI~ITTELFORSCH{;NG in ihrer Gesamtheit einen nicht unwesent- lichen Teil unseres heutigen \Vissens in zusammenfassender Darstellung enthalten. Del' Herausgeber schatzt sich gliicklich und ist dankbar fiir die Moglichkeit. mit diesem \Verk das umfassende \Vissen del' Autoren. die ausnahmslos mitten in del' aktiven Forschung stehen. zahlreichen in del' Al'zneimittelforschung Tatigen vel'- mitteln zu diiden. Unser Forschungsgebiet befindet sich zur Zeit in einer Phase des Umbruchs. del' Besinnung auf Vergangenes und del' lJmorientierung auf die Zukunft. Diese Situation ist zum Teil del' aussere Ausdruck und das Resultat del' stiirmischen Entwicklung del' letzten 20 Jahre. die in del' Geschichte del' Medizin ohne Pal'allele dasteht. und deren Folgeerscheinungen noch gar nicht iiberblickt werden konnen.
Neurohormones and Neurohumors
Structure and Function of Regulatory Mechanisms
AvJ. Ariëns Kappers
Häftad, Engelska, 1969
568 kr
Skickas inom 10-15 vardagar
Having accepted the task to organize, in Amsterdam, an international Congress in behalf of the International Sodety for Neurovegetati'V'e Research such as is held every second year, it occurred to me that it might be worth while to change its usual pattern somewhat. Instead of giving merely the opportunity for l'eading a nurnber of rather short free papers, more or less grouped in many categories, we decided to start with a symposium on a special topic 'to be dealt with from several aspects by a numbe·r of invited speakers, the last day of the congress being only available for short free communications. The central topic for the symposium finally chosen was "Neurohormones and N eurohumors" as this subject is of interest :to many morphologists, physiologists, pharmacologists, neuro-endocrinologists, biochemists and clini cians, and belongs to a rapidly expanding Held of research. Moreover, it appeared to us that there is some confusion about the defini tion of these terms which are not seLdom used indifferently. I hoped that such a symposium would contribute 1to a clearer apprehension of the terms based on morphological, physiological and biochemical criteria as well as to a clearer understanding of some problems involved which will have to be subjects of future investigations.
Neurohormones and Neurohumors
Structure and Function of Regulatory Mechanisms
AvJ. Ariens Kappers
E-bok
PDF, Engelska, 2013
755 kr
Läs direkt efter köp
Having accepted the task to organize, in Amsterdam, an international Congress in behalf of the International Sodety for Neurovegetati''V''e Research such as is held every second year, it occurred to me that it might be worth while to change its usual pattern somewhat. Instead of giving merely the opportunity for l''eading a nurnber of rather short free papers, more or less grouped in many categories, we decided to start with a symposium on a special topic ''to be dealt with from several aspects by a numbe·r of invited speakers, the last day of the congress being only available for short free communications. The central topic for the symposium finally chosen was "Neurohormones and N eurohumors" as this subject is of interest :to many morphologists, physiologists, pharmacologists, neuro-endocrinologists, biochemists and clini cians, and belongs to a rapidly expanding Held of research. Moreover, it appeared to us that there is some confusion about the defini tion of these terms which are not seLdom used indifferently. I hoped that such a symposium would contribute 1to a clearer apprehension of the terms based on morphological, physiological and biochemical criteria as well as to a clearer understanding of some problems involved which will have to be subjects of future investigations.
Neurovegetative Transmission Mechanisms
Proceedings of the International Neurovegetative Symposium, Tihany, June 19–24, 1972
AvJ. Ariens Kappers,B. Csillik
E-bok
PDF, Engelska, 2013
755 kr
Läs direkt efter köp
As a former president of the International Society for Neuro vegetative Research and as a co-editor it is a pleasure to write a short introduction to the present volume which contains the proceedings of an international symposium, held at Tihany, Hungary, June 19-24, 1972, under the auspices of the Society mentioned above. The meeting, which was organized by Professor B. Csillik, Szeged, Hungary, who also acted as president, took place at the Tihany Biological Institute, most beautifully situated at lake Balaton. Such international symposia of the International Society for Neurovegetative Research have been organized at irregular intervals in several different countries. Members of the International Society are, automatically, the members of National Societies for Neuro vegetative Research, active in some European countries and in Japan, as well as individuals taking interest in the aim of the International Society. From its foundation, in 1953, on the goal of the Society has always been the advancement of neurovegetative research as per formed by both, workers in the basic sciences and medical prac titioners doing scientific work. Therefore, symposia of the Inter national Society for Neurovegetative Reseanh are international forums where pure scientific work as well as clinical investigations and clinical experience can be discussed. In this way, the Society has always been trying to bridge the gap between pure and applied science in the medical field which is so often felt to exist, especially at the present time often suffering from overspecialization.
Del 11 - Journal of Neural Transmission. Supplementa
Neurovegetative Transmission Mechanisms
Proceedings of the International Neurovegetative Symposium, Tihany, June 19–24, 1972
AvB. Csillik,J. Ariens Kappers
Häftad, Engelska, 2012
568 kr
Skickas inom 10-15 vardagar
As a former president of the International Society for Neuro vegetative Research and as a co-editor it is a pleasure to write a short introduction to the present volume which contains the proceedings of an international symposium, held at Tihany, Hungary, June 19-24, 1972, under the auspices of the Society mentioned above. The meeting, which was organized by Professor B. Csillik, Szeged, Hungary, who also acted as president, took place at the Tihany Biological Institute, most beautifully situated at lake Balaton. Such international symposia of the International Society for Neurovegetative Research have been organized at irregular intervals in several different countries. Members of the International Society are, automatically, the members of National Societies for Neuro vegetative Research, active in some European countries and in Japan, as well as individuals taking interest in the aim of the International Society. From its foundation, in 1953, on the goal of the Society has always been the advancement of neurovegetative research as per formed by both, workers in the basic sciences and medical prac titioners doing scientific work. Therefore, symposia of the Inter national Society for Neurovegetative Reseanh are international forums where pure scientific work as well as clinical investigations and clinical experience can be discussed. In this way, the Society has always been trying to bridge the gap between pure and applied science in the medical field which is so often felt to exist, especially at the present time often suffering from overspecialization.
Lone Star Law
A Legal History of Texas
AvMichael Ariens
Häftad, Engelska, 2016
302 kr
Tillfälligt slut
Michael Ariens proves that no state possesses a richer or more surprising legal history than Texas. In narrative as engaging as it is accessible, he has produced an overarching consideration of Lone Star law and legal culture something notably missing in other Texas histories. After taking readers chronologically from early settlement through 1920, Ariens focuses on particular areas of Texas law, including property, family, business, criminal, and civil harms (tort), and on the history of Texas's legal profession itself. Through illuminating and utterly Texan particulars, Ariens helps us understand a place at once southern and western, Spanish and Mexican, republic and state.
Kommissariens löfte
AvFriedrich Dürrenmatt
Häftad, Svenska, 2025
4,8 utav 5 stjärnor. Totalt antal röster:(5)
207 kr
"Denna urspännande, ultramelankoliska och nu lyckligtvis återutgivna minor classic vars svårförglömliga huvudperson är en briljant kommissarie som förspiller livet i sin nitiska jakt på en flickmördare" Dagens Nyheter
"En på samma gång spännande och tankeväckande (rekonstruerad) kriminalroman" Kult MagasinLiket av en flicka upptäcks i skogarna utanför den schweiziska byn Mägendorf. Kommissarie Matthäi berörs djupt av tragedin och svär inför flickans föräldrar att han ska hitta mördaren. Men medan byborna redan bestämt sig för vem som är den skyldige och blir lättade när han hänger sig så är Matthäi inte lika säker …
Kommissariens löfte är den lika spännande som gripande historien om att kämpa för rättvisan och stå upp för sin sak – och priset som detta kommer med.
Efterord av Lena Andersson.
När nyfikenhet, driv och kreativitet möts : bibliotekariens roll som producent och utvecklare
Häftad, Svenska, 2021
143 kr
Skickas
Kompetens, nyfikenhet, initiativförmåga och driv. Det är teman som förenar alla texter i den här antologin. Vad som också är gemensamt är skribenternas ambition att utveckla biblioteksverksamheterna de verkar inom. Det här är den tredje och avslutande delen i en triologi över bibliotekariens yrke och olika roller. Serien är en del i Kungliga bibliotekets arbete med att göra djuplodande temastudier av bibliotekarieprofessionen. Den första delen, Bortom förlägenheten, utgick från bibliotekariens roll som pedagog. Den andra delen, Världen där utanför, fokuserade på rollen som omvärldsbevakare. Nu får vi en inblick i bibliotekariens roll som producent och utvecklare av bibliotekens olika verksamheter. Välkomna in i bibliotekariens mångfacetterade värld: När nyfikenhet, driv och kreativitet möts. Bibliotekariens roll som producent och utvecklare.