European Society for Medical Oncology Handbooks – serie

Using state-of-the-art and evidence-based literature references and reviews, the authors present an overview of translational research that is both reliable and easily understood. The book begins with principles of normal cell biology and normal immunology. It examines tumor biology and basic tumor immunology. It then discusses limitless replicative potential, self-sufficiency in growth signals, insensitivity to anti-growth signals, and evading apoptosis. The book concludes with a chapter on angiogenesis, tissue invasion and metastasis, treatment, and evaluation of treatment.

This handbook describes and discusses cancer diagnosis and treatment evaluation, focusing on some key issues of the clinical method of medical oncologists. It helps medical oncologists to recognize these issues as worth learning and as a subject of research themselves.

Young medical oncologists, who may often find themselves faced by major complications caused by cancer or by cancer treatment, will welcome this handbook as a highly useful tool to develop their knowledge and skills in the area.Initiated by the European Society for Medical Oncology’s (ESMO) Young Medical Oncologists Working Group, this succinct text has been written by a distinguished team of young medical oncologists and senior figures in the field, and is designed to provide oncologists with a secure practical grounding in the correct courses of action to follow in an emergency.The key topics covered include:* cardiovascular complications* neurological complications* renal and urologic complications* metabolic complications* respiratory complications* gastro-intestinal complications* hematologic complications* cancer pain.

Cancer is a disease related to ageing, and the proportion of senior patients increases worldwide. While the proportion of persons beyond age 70 is still small in developing countries, their numerous population means that there are more "elderlies" in India than in Europe. This book reflects the state of the art in the management of senior adults with cancer. This handbook leaves ample space for chapters that help in the delicate decisionmaking process, which should lead to the best therapy, adapted not only to the disease but also to the person who suffers from it.

The treatment of patients with advanced cancer presents a special set of problems. The cancer itself poses significant challenges related to treatment, and the chemotherapy involved can often induce its own set of issues. In these difficult cases, psychiatric problems and palliative care often come to the forefront of a physician's concerns. The book examines these and other issues, including metabolic, gastrointestinal, respiratory, genitourinary, dermatological, and neurological problems that occur in advanced cancer cases. The book also addresses the unique problems of geriatric patients.