Green Bioactive Heterocycles – serie

Non-conventional synthetic methods may provide new and green methods for the preparation of bioactive heterocycles. These methods, such as microwave and ultrasound assisted synthesis, biocatalysis, photochemistry and electrosynthesis use less energy and may produce less waste to get the desired products when compared to traditional methods. This book explores the use of these methods when synthesizing various biologically relevant heterocyclic scaffolds. THE SERIES: GREEN BIOACTIVE HETEROCYCLES Heterocycles are a widely utilized group of molecules as they often contain bioactivity that is useful in drug development, agriculture, and other applications. However, their synthesis remains challenging with diffi cult to control functional groups. With a greater focus on sustainable synthesis practices, there is a need to develop greener synthetic methods for the synthesis of structurally diverse bioactive heterocyclic scaffolds. This series aims to do so, by collecting developments into common themes.

Non-metal catalysis may provide new and green methods for obtaining bioactive heterocycles. Many catalysts contain metals, which can be toxic, energy intensive to remove, and require mining of the source materials. By utilizing metal-free catalysts we avoid these issues. This book explores the use of non-metal catalysts when synthesizing various heterocyclic structures with bioactivity.

The solvent-free approach provides green and alternative synthetic methods for obtaining diverse bioactive heterocycles. The solvent is frequently the primary component of synthetic protocol and contributes to significant waste. Additionally, its removal processes are energy intensive and substantial. This book explores different solvent-free procedures for efficiently synthesising heterocyclic analogues of immense biological importance and other applications.

Multicomponent synthesis may provide new and green routes for obtaining bioactive heterocycles. These methods produce less organic waste due to no longer removing solvent and other components between reaction steps. It can be applied to the synthesis of heterocycles with reactions such as the Biginelli reaction. This book explores the use of multi-component reactions for various heterocyclic structures with bioactivity.

Bioactive Three-Membered Heterocycles provides detailed information on the green synthesis of the structurally diverse pharmaceutically active three-membered heterocycles. It covers both synthesis and biological aspects and highlights the role of three-membered heterocycles in drugs and drug designing. It also includes naturally occurring bioactive three-membered heterocycles.

Bioactive Four-Membered Heterocycles provides detailed information on the green synthesis of the structurally diverse pharmaceutically active four-membered heterocycles. It covers both synthesis and biological aspects and highlights the role of four-membered heterocycles in drugs and drug designing. It also includes naturally occurring bioactive four-membered heterocycles.

Bioactive Five-Membered Heterocycles provides detailed information on the green synthesis of the structurally diverse pharmaceutically active five-membered heterocycles. It covers both synthesis and biological aspects and highlights the role of five-membered heterocycles in drugs and drug designing. It also includes naturally occurring bioactive five-membered heterocycles.