Molecular Biology Intelligence Unit – serie
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136 produkter
Telomerases, Telomeres and Cancer
Av Guido Krupp, Reza Parwaresch
Inbunden, 2003
2253 kr
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This volume provides broad insights to the most recent discoveries in telomere biology, with current applications in tumour diagnostics and future potentials in therapy. Special features of diverse organisms are presented, with ciliates, the "telomerase discoverer organisms"; yeasts, the "molecular …
CDK-Activating Kinase (CAK)
Av Philipp Kaldis, Philipp Kaldis
Inbunden, 2003
1098 kr
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This volume aims to extract and summarize all information about CAK by pointing out commonly accepted facts and unresolved issues. It takes the reader from yeast to mammals and describes all areas that CAK is thought to be involved in. This volume is designed to serve newcomers to the field as well …
Nuclear Envelope Dynamics in Embryos and Somatic Cells
Av Philippe Collas, Philippe Collas
Inbunden, 2003
1098 kr
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This volume provides an exhaustive review of the most current knowledge of the composition, architecture and dynamics of the nuclear envelope. In contrast to other comprehensive works on cellular membranes in general, this book is the first to specifically address the nuclear envelope. Experts in …
Caspases: Their Role in Cell Death and Cell Survival
Av Orlando J. Castejon, Marek Los m. fl.
Inbunden, 2003
2188 kr
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The volume offers insight into the key research topics that involve caspases. Leading experts from various areas of biology and medicine have compiled this volume so that both the novice and the professional will use this as the main reference for caspases for years to come. The reader will learn …
Ceramide Signaling
Inbunden, 2003
1098 kr
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The volume assembles current information on the role of ceramide as a signalling molecule in 16 chapters written by leading workers in this area. Specific attention is given to mechanisms of analysis of ceramide and its biophysical properties, on enzymes of ceramide metabolism and down-stream …
Regulation of G1 Phase Progression
Inbunden, 2003
1643 kr
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In this contribution, several specialists describe the current knowledge on the molecular networks that regulate cell cycle progression, with an emphasis on the G1 phase of the cell cycle. The first part of Regulation of G1 Phase Progression is concerned with the individual molecules that form the …
Intracellular Pathogens in Membrane Interactions and Vacuole Biogenesis
Inbunden, 2004
1692 kr
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This book provides information on the molecular interactions between host cell organelles and pathogens, which have developed strategies to survive within infected cells. Chapters are grouped into five sections: I. Endocytosis and phagocytosis. Collectively, the chapters of this section review …
Annexins
Biological Importance and Annexin-Related Pathologies
Inbunden, 2003
1130 kr
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The Annexins is focused on a specific family of calcium and membrane-binding proteins, annexins, ubiquitously spread within living organisms, including animals, plants and fungi. The volume covers important areas of annexinology. The characterization of structural-functional relationship within the …
I Domains in Integrins
Inbunden, 2003
1692 kr
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In vertebrates, the integrin family includes 24 members. As the alpha-chains were sequenced, some were observed to have an inserted domain similar to the A domain in several matrix and complement proteins. This inserted ligand binding domain is interactive and was called the I domain in integrins. …
Cystic Fibrosis Transmembrane Conductance Regulator
Av Kevin L. Kirk, David C. Dawson
Inbunden, 2003
1643 kr
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The CFTR chloride channel is one of the most well studied transport proteins in biology. Yet there remain many mysteries about the functional properties and biological roles of this ABC transporter. The Cystic Fibrosis Transmembrane Conductance Regulator addresses a select series of `hot' topics …
Wnt Signaling in Development
Inbunden, 2003
1643 kr
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Wnt genes code for a family of secreted glycoproteins which fulfil important functions during the development of vertebrates and invertebrates. Wnts regulate as different aspects as differentiation, proliferation, cell migration, and cell polarity. Wnt proteins are able to activate different …
Translation Mechanisms
Av Jacques Lapointe, Lea Brakier-Gigras
Inbunden, 2003
2188 kr
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Translation Mechanisms provides investigators and graduate students with overviews of recent developments in the field of protein biosynthesis that are fuelled by the explosive and synergic growth of structural biology, genomics, and bioinformatics. The outstanding progress in our understanding of …
Voltage-Gated Calcium Channels
Inbunden, 2005
2188 kr
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oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar macological …
Nramp Family
Av Mathieu Cellier, Philippe Gros
Inbunden, 2004
1643 kr
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This book is the first comprehensive volume on the "Nramp family", highlighting the physiological importance of Nramp proteins as metal transporters. The molecular knowledge of these membrane proteins is presented from an evolutionary perspective, considering Nramp cellular function and mechanism …
B7-CD28 Family Molecules
Av Lieping Chen
Inbunden, 2003
1692 kr
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The B7-CD28 family molecules are probably the most intensively studied receptor-ligand systems in the field of immunology. This is evident from the explosive accumulation of literature, particularly in the last ten years. Recent years have witnessed rapid discoveries and characterization of new …
Immunobiology of Carbohydrates
Av Simon Wong, Gemma Arsequell
Inbunden, 2003
2590 kr
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This book is unique in providing pertinent information on the various established roles carbohydrate play in the immune system and how the innate and adaptive immune systems respond to this type of microbial antigens. The editors selected only topics that have established basic and clinical …
Calreticulin
Av Paul Eggleton, Marek Michalak
Inbunden, 2003
1692 kr
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The book focuses on the latest discoveries on calreticulin, calnexin and other endoplasmic reticulum proteins. Calreticulin has been implicated to affect diverse cellular function and play a role in many pathologies including protein folding disorders, cardiac pathologies, cancer and autoimmunity. …
Insulin-like Growth Factor Receptor Signalling
Av Derek Leroith, Walter Zumkeller m. fl.
Inbunden, 2003
2253 kr
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Insulin-like growth factors are ubiquitously expressed and are crucial for growth and function of almost all cells. Together with their binding proteins and receptors, they form a widely studied biological system involving many proteins and characterized by complex interactions. In addition to its …
Molecular Biology of the Parathyroid
Av Neveh-Many, Tally Naveh-Many
Inbunden, 2005
1692 kr
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aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu M lar calcium levels, by acting on bone, kidney and intestine. The recent intro duction of PTH as a …
Protein Kinase C
Inbunden, 2004
1643 kr
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Protein Kinase C is a pivotal component of the mechanism that allows a cell to respond to its changing environment. In this book, the most significant advances in recent basic research on Protein Kinase C are explained by active researchers in the field. The first seven chapters provide a …
Nucleolus
Inbunden, 2004
1643 kr
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As the first comprehensive overview of the nucleolus since 1985, The Nucleolus covers our current understanding of the cell nucleolus, including its role in ribosome assembly and its additional newly-discovered activities. The eighteen chapters have been written by experts who are actively engaged …
Eukaryotic DNA Damage Surveillance and Repair
Inbunden, 2004
1643 kr
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Eukaryotic DNA Damage Surveillance and Repair contains chapters from experts in the field of DNA damage detection, repair, and cell cycle control. The work reviews current understanding of how different types of DNA damage are detected and focuses on how these surveillance mechanisms are coupled to …
Biogenesis of Cellular Organelles
Inbunden, 2004
1692 kr
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The Biogenesis of Cellular Organelles represents a comprehensive summary of recent advances in the study of the biogenesis and functional dynamics of the major organelles operating in the eukaryotic cell. This book begins by placing the study of organelle biogenesis in a historical perspective by …
Rho GTPases
Av Marc H. Symonds, Marc Symons m. fl.
Inbunden, 2004
1643 kr
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Members of the Rho family of small GTP-binding proteins (GTPases) are key signal transduction proteins that mediate signals initiated by growth factors, cytokines and cell adhesion proteins. Our knowledge about Rho GTPases has rapidly expanded over the past several years and Rho GTPases is the …
Viral Genome Packaging: Genetics, Structure, and Mechanism
Inbunden, 2005
1643 kr
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Viral Genome Packaging focuses on the process of genome "packaging" within a pre-formed viral procapsid. The chapters of this book concentrate on the biochemistry, enzymology and structural aspects of the genome packaging machinery. This book defines a broad mechanistic basis for the process across …
Zinc Finger Proteins
From Atomic Contact to Cellular Function
Av Shiro Iuchi, Natalie Kuldell
Inbunden, 2005
1643 kr
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In the early 1980s, a few scientists started working on a Xenopus transcription factor, TFIIIA. They soon discovered a novel domain associated with zinc, and named this domain "zinc finger. " Th e number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, …
Selective Sweep
Av Dmitry Nurminsky, Dmitry I. Nurminsky
Inbunden, 2005
1098 kr
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Selective Sweep deals with the theory and practice of detection of recent adaptive evolution at the genomic level from the patterns of DNA polymorphism. Recent advances in genomic sequencing provide the background for analysis of polymorphic sites in large chromosomal regions or even in whole …
Cell Growth and Cholesterol Esters
Av Alessandra Pani, Sandra Dessì
Inbunden, 2003
1130 kr
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This volume is devoted to cancer and atherosclerosis, two of the most important proliferative pathologies in the world today. This book provides a useful point of reference on the mechanisms that link cholesterol esters to cell proliferation, summarizing the latest advances both in basic science …
Toll and Toll-Like Receptors:
An Immunologic Perspective
Inbunden, 2005
1692 kr
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Toll Receptors and the Renaissance of Innate Immunity Elizabeth H. Bassett and Tina Rich Overview n the last few pages of Immunology: The Science of Self-Nonself Discrimination Jan Klein ponders on what he would study if he were to start over in the lab. ^ Dismissing the I antibody, MHC, the T-cell …
Rise and Fall of Epithelial Phenotype
Concepts of Epithelial-Mesenchymal Transition
Inbunden, 2005
1643 kr
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Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT). The Rise and Fall of Epithelial Phenotype is the first …
