Pharmaceutical Science Series – serie
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3 produkter
3 produkter
Inbunden, Engelska, 2004
4 139 kr
Skickas inom 5-8 vardagar
Recent advances in cytotoxins and immunotoxins are accelerating our understanding of cancer and leading to more effective therapeutic treatments. Although a large number of articles have been published on these cytotoxins and immunotoxins, this important information has yet to be compiled into one comprehensive resource.For the first time, Cytotoxins and Immunotoxins for Cancer Therapy: Clinical Applications presents state-of-the-art information on various cytotoxins and immunotoxins in a single, highly anticipated publication. The editors bring together leading researchers to summarize their work and discuss clinical trial data concerning some of the most widely studied tumors. The book describes Pseudomonas exotoxin (PE)-based immunotoxins and presents the latest results from clinical trials for the treatment of recurrent glioblastoma and other human cancers. It reviews the role of ricin-based immunotoxins for the treatment of lymphoma, explores several DT-based immunotoxins, and details the preclinical and clinical development of the first FDA-approved cytotoxin.With a focus on clinical developmental approaches to the use of cytotoxins and immunotoxins, this book discusses exciting possibilities for cancer therapy. It is a valuable resource for scientists, researchers, and clinicians involved in the development of new treatments that can help keep cancer under control, and may ultimately lead to a cure.
Inbunden, Engelska, 2000
2 522 kr
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The Beta-3 Adrenoreceptor plays an important role in regulating human fat storage and variants of this receptor are thought to be relevant to diabetes.In addition to the major interest in obesity and diabetes expressed by the pharmaceutical industry, increasing numbers of academic groups are attracted by this general research area. This renewed interest is of course in part stimulated by available financing from industry. It also reflects the growing realisation that metabolism remains an open frontier: little is known about adipocyte sub-populations, specific markers, or endocrine functions. Research on the ß3 adrenoreceptor and discussion about the hypothetical ß4 adrenoreceptor is currently stimulating considerable interest which will certainly be satisfied by this volume. The Beta-3 Adrenoreceptor will appeal to readers at graduate and post-graduate levels of all major universities and other research and education institutes.
Inbunden, Engelska, 2001
2 726 kr
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The ubiquitous presence of glutamate and GABA receptors in the nervous system makes these receptor systems pivotal to our understanding of neurotransmission. Cloning of the molecular components of these receptor systems has provided insights to the selectivity of many drugs and detailed characterisation at the molecular level is emerging. Moreover, continuous development of novel and selective drugs has revealed detailed information on the mechanism of receptor activation and regulation. However, the rapid development of different aspects of glutamate and GABA receptor research makes it increasingly difficult to establish a general view of the field. Studies of the receptors are a multi-disciplinary task employing many specialised techniques. This book conveys recent discoveries in a framework of the basic concepts in the field of glutamate and GABA receptor research. Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology is suitable for postgraduate students studying ligand gated channels but also beneficial for industrial and academic research scientists in both the glutamate and GABA field. Universities offering programs in neuroscience, molecular pharmacology or medicinal chemistry will find this a valuable reference.