Translational Medicine – serie

Considering the impact of translational breakthroughs on the early detection, diagnosis, prevention, and treatment of breast cancer, this all-encompassing guide collects cutting-edge research on the most promising strategies and agents likely to impact the management and long-term outcomes of women with breast cancer. This book will provide current information on rapidly evolving translational therapies, as well as improved strategies for the selection of patients for these treatments.

Multiple myeloma is the second most prevalent hematological malignancy, with over 55,000 new cases diagnosed each year. This exciting new text, edited by lauded authorities on the topic, stands as the only available reference to assemble, review, and synthesizes the latest studies on translational therapies and clearly explains the impact of molecular pathogenesis, biology, and prognostic factors on the diagnosis, prognosis, and individualization of treatment and the development of novel therapeutic options for patients with myeloma.Moving from the bench to the bedside to the forefront of therapeutic development, this source:helps clinicians and researchers effectively deploy therapeutic strategies into clinical practicereflects trends in the use of agents which target both the tumor cell and its bone marrow microenvironment to overcome resistance to conventional therapiesconsiders the critical role of the bone marrow microenvironment in the regulation of growth, survival, and homing of multiple myelomadiscusses novel therapies in phase I and phase II trials, focusing specifically on therapeutic options for patients with newly diagnosed or relapsed/refractory multiple myelomaaddresses novel therapies for other plasma cell disorders, and provides the framework for the design of next generation agents and combination therapiescovers the entire scope of translational work in multiple myeloma, from advances in molecular pathogenesis, to prognostic factors, immunotherapy, and new options for newly diagnosed and relapsed multiple myeloma patients

Written with a broader perspective and knowledge, Cancer Supportive Care: Advances in Therapeutic Strategies presents state-of-the-art management options for the full range of symptoms, toxicities, and complications experienced by cancer patients. In addition to "bread and butter" topics such as pain control and nausea and vomiting, the book contains unique, ground-breaking discussions of symptom measurement, the role of growth factors, and late effects and cancer survivorship.Written by key opinion leaders in the field, Cancer Supportive Care: Advances in Therapeutic Strategies: assembles and synthesizes state-of-the-art information into one convenient resource, helping busy clinicians learn the most effective supportive care strategies availablediscusses emerging therapies and approachescovers topics not included in other cancer supportive care books, such as measurement of symptoms, growth factors, thromboembolism, skeletal complications, fatigue, the elderly cancer patient, cancer survivorship, and alternative and integrative therapies

Pharmacogenetics is becoming increasingly relevant in the diagnosis, treatment, and recovery of cancer patients. A major problem facing oncologists is the outstanding varied efficacy of treatment. Promising advances in pharmacogenetics have allowed the development of effective agents which will enable personalized cancer chemotherapy to become routine for the clinical practice. Written by experts in the field and combining information that is unable to be found in a single source volume, Pharmacogenetics of Breast Cancer: combines a complete overview of pharmacogenetics and how it relates to breast oncology for diagnosis, treatment, and the recovery of patients using an individualized therapy modelis the first single source reference demonstrating the application of pharmacogenetics in the care of breast cancer patientsenables physicians a coherent interpretation of the emerging science of pharmacogenetics, aiding them to incorporate individual therapies in their own practicegives practical guidance on various forms of specimen collection, tissue selection, and handling procedures