Wiley Series in Modeling and Simulation – serie

An introduction to state-of-the-art modeling and simulation approaches for social and economic determinants of population healthNew Horizons in Modeling and Simulation for Social Epidemiology and Public Health offers a comprehensive introduction to modeling and simulation that addresses the many complex research questions in social epidemiology and public health. This book highlights a variety of practical applications and illustrative examples with a focus on modeling and simulation approaches for the social and economic determinants of population health.The book contains classic case examples in agent-based modeling (ABM) as well as essential information on ABM applications to public health including for infectious disease modeling, obesity, and tobacco control. This book also surveys applications of microsimulation (MSM) including of tax-benefit policies to project impacts of the social determinants of health.Specifically, this book: Provides an overview of the social determinants of health and the public health significance of addressing the social determinants of healthGives a conceptual foundation for the application of ABM and MSM to study the social determinants of healthOffers methodological introductions to both ABM and MSM approaches with illustrative examplesIncludes cutting-edge systematic reviews of empirical applications of ABM and MSM in the social sciences, social epidemiology, and public healthDiscusses future directions for empirical research using ABM and MSM, including integrating aspects of both ABM and MSM and implications for public health policiesWritten for a broad audience of policy analysts, public planners, and researchers and practitioners in public health and public policy including social epidemiologists, New Horizons in Modeling and Simulation for Social Epidemiology and Public Health offers a fundamental guide to the social determinants of health and state-of-the-art applications of ABM and MSM to studying the social and economic determinants of population health.

A modern guide to computational models and constructive simulation for personalized patient care using the Digital PatientThe healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers.The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible humanThe physiological humanThe virtual humanResearch in systems biologyMulti-scale modelingPersonalized medicineSelf-quantificationVisualizationComputational modelingInterdisciplinary collaborationThe Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.

Presents an overview of the complex biological systems used within a global public health setting and features a focus on malaria analysisBridging the gap between agent-based modeling and simulation (ABMS) and geographic information systems (GIS), Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development of agent-based models (ABMs) by following a conceptual and biological core model of Anopheles gambiae for malaria epidemiology. Using spatial ABMs, the book includes mosquito (vector) control interventions and GIS as two example applications of ABMs, as well as a brief description of epidemiology modeling. In addition, the authors discuss how to most effectively integrate spatial ABMs with a GIS. The book concludes with a combination of knowledge from entomological, epidemiological, simulation-based, and geo-spatial domains in order to identify and analyze relationships between various transmission variables of the disease.Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology also features: Location-specific mosquito abundance maps that play an important role in malaria control activities by guiding future resource allocation for malaria control and identifying hotspots for further investigationDiscussions on the best modeling practices in an effort to achieve improved efficacy, cost-effectiveness, ecological soundness, and sustainability of vector control for malariaAn overview of the various ABMs, GIS, and spatial statistical methods used in entomological and epidemiological studies, as well as the model malaria studyA companion website with computer source code and flowcharts of the spatial ABM and a landscape generator tool that can simulate landscapes with varying spatial heterogeneity of different types of resources including aquatic habitats and housesSpatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology is an excellent reference for professionals such as modeling and simulation experts, GIS experts, spatial analysts, mathematicians, statisticians, epidemiologists, health policy makers, as well as researchers and scientists who use, manage, or analyze infectious disease data and/or infectious disease-related projects. The book is also ideal for graduate-level courses in modeling and simulation, bioinformatics, biostatistics, public health and policy, and epidemiology.

Presents information sources and methodologies for modeling and simulating banking system stabilityCombining both academic and institutional knowledge and experience, Banking Systems Simulation: Theory, Practice, and Application of Modeling Shocks, Losses, and Contagion presents banking system risk modeling clearly within a theoretical framework. Written from the global financial perspective, the book explores single bank risk, common bank exposures, and contagion, and how these apply on a systemic level. Zedda approaches these simulation methods logically by providing the basic building blocks of modeling and simulation, and then delving further into the individual techniques that make up a systems model.In addition, the author provides clear and detailed explanations of the foundational research into the mathematical and legal concepts used to analyze banking risk problems, measures and data for representing the main banking risk sources, and the major problems researchers are likely to encounter. There are numerous software descriptions throughout, with references and tools to help readers gain a proper understanding of the presented techniques and possibly develop new applications and research. The book concludes with an appendix that features real-world datasets and models.In addition, this book:• Provides a comprehensive overview of methods for analyzing models and simulating risk for banking and financial systems• Provides a clear presentation of the technical and legal concepts used in banking regulation• Presents unique insights from an expert’s perspective, with specific coverage of assessing risks and developing what-if analyses at the systems level• Concludes with a discussion of applications, including banking systems regulation what-if tests, cost-benefit analysis, evaluations of banking systems stability effects on public finances, dimensioning, and risk-based contributions for Deposit Guarantee Schemes (DGS) and Resolution FundsBanking Systems Simulation: Theory, Practice, and Application of Modeling Shocks, Losses, and Contagion is ideal for banking researchers focusing on computational methods of analysis as well as an appropriate reference for graduate-level students in banking, finance, and computational methods.Stefano Zedda is Researcher in Financial Mathematics at the University of Cagliari in Italy and qualified as associate professor in banking and corporate finance. His research is mainly focused on quantitative analyses for banking and finance, with a particular focus on banking systems modeling and simulation. In 2008, Zedda developed the mathematical modeling and software implementation of the Systemic Model for Banking Originated Losses (SYMBOL), further developed during his activity at the European Commission. The Commission subsequently adopted it as a standard tool for testing banking regulation proposals. Stefano Zedda’s research interests include banking, financial mathematics, and statistics, specifically simulation of banking and financial systems stability, banking regulation impact assessment, and interactive agent simulation.

The definite guide to the theory, knowledge, technical expertise, and ethical considerations that define the M&S professionFrom traffic control to disaster management, supply chain analysis to military logistics, healthcare management to new drug discovery, modeling and simulation (M&S) has become an essential tool for solving countless real-world problems. M&S professionals are now indispensable to how things get done across virtually every aspect of modern life. This makes it all the more surprising that, until now, no effort has been made to systematically codify the core theory, knowledge, and technical expertise needed to succeed as an M&S professional.This book brings together contributions from experts at the leading edge of the modeling and simulation profession, worldwide, who share their priceless insights into issues which are fundamental to professional success and career development in this critically important field. Running as a common thread throughout the book is an emphasis on several key aspects of the profession, including the essential body of knowledge underlying the M&S profession; the technical discipline of M&S; the ethical standards that should guide professional conduct; and the economic and commercial challenges today’s M&S professionals face.• Demonstrates applications of M&S tools and techniques in a variety of fields—such as engineering, operations research, and cyber environments—with over 500 types of simulations• Highlights professional and academic aspects of the field, including preferred programming languages, professional academic and certification programs, and key international societies• Shows why M&S professionals must be fully versed in the theory, concepts, and tools needed to address the challenges of cyber environmentsThe Profession of Modeling and Simulation is a valuable resource for M&S practitioners, developers, and researchers working in industry and government. Simulation professionals, including administrators, managers, technologists, faculty members, and scholars within the physical sciences, life sciences, and engineering fields will find it highly useful, as will students planning to pursue a career in the M&S profession.“ …nearly three dozen experts in Modeling and Simulation (M&S) come together to make a compelling case for the recognition of M&S as a profession… Important reading for anyone seeking to elevate the standing of this vital field.”Alfred (Al) Grasso, President & CEO, The MITRE CorporationAndreas Tolk, PhD, is Technology Integrator for the Modeling, Simulation, Experimentation, and Analytics Division of The MITRE Corporation, an adjunct professor in the Department of Engineering Management and Systems Engineering and the Department for Modeling, Simulation, and Visualization Engineering at Old Dominion University, and an SCS fellow.Tuncer Ören, PhD, is Professor Emeritus of Computer Science at the University of Ottawa. He is an SCS fellow and an inductee to SCS Modeling and Simulation Hall of Fame. His research interests include advancing methodologies, ethics, body of knowledge, and terminology of modeling and simulation.